Cheryl Elizabeth Grace Leyns

  • University of Wisconsin-Parkside (2013)

  • Molecular Cell Biology

  • David M. Holtzman, M.D.

  • The Holtzman lab is focused on understanding the pathology of Alzheimer’s disease and developing approaches to treatment.

  • leynsc@go.wustl.edu

Research

My thesis work in the Holtzman lab consists of understanding tau pathobiology and developing better approaches to the treatment of tauopathies. Tau is a microtubule binding protein that forms neurotoxic aggregates in a multitude of neurodegenerative diseases including but not limited to progressive supranuclear nuclear palsy, frontotemporal dementia, and Alzheimer`s disease. My projects center around understanding how tau aggregates propagate, how immunotherapy functions to prevent this propagation, and designing long-term approaches for the administration of anti-tau antibodies.

Last Updated: 9/10/2015 9:21:24 AM

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