• University of Wisconsin-Madison (2011)

  • Molecular Cell Biology

  • Babak Razani, M.D., Ph.D.

  • The Autophagy-Lysosome Degradation System in Metabolic Disease

  • trent.evans@wustl.edu



Graduate Publications:

1) Target Acquired: Selective Autophagy in Cardiometabolic Disease. Evans TD, Sergin I, Zhang X, Razani B. Sci Signal Feb 2017.

2) Modulating Oxysterol Sensing to Control Macrophage Apoptosis and Atherosclerosis. Evans TD, Sergin I, Zhang X, Razani B. Circ Res. 2016 Dec 9; 119(12):1258-1261.

3) Exploiting Macrophage Autophagy-Lysosomal Biogenesis as a Therapy for Atherosclerosis. Sergin I, Evans TD, Zhang X, Bhattacharya S, Stokes CJ, Song E, Ali S, Dehestani B, Holloway KB, Micevych PS, Javaheri A, Crowley JR, Ballabio A, Schilling JD, Epelman S, Weihl CC, Diwan A, Fan D, Zayed MA, Razani B. Nature Communications. 2017 Jun 7;8:15750.

4) Transcription Factor EB regulates Macrophage Polarization in the Tumor Microenvironment. Fang L, Hodge J, Saaoud F, Wang J, Iwanowycz, Wang Y, Hui Y, Evans TD, Razani B, Fan D. Oncoimmunology, 2017. June (6) 5.

5) Inclusion bodies enriched for p62 and polyubiquitinated proteins in macrophages protect against atherosclerosis.
Sergin I, Bhattacharya S, Emanuel R, Esen E, Stokes CJ, Evans TD, Arif B, Curci JA, Razani B.
Sci Signal. 2016 Jan 5;9(409):ra2.

6) Degradation and beyond: the macrophage lysosome as a nexus for nutrient sensing and processing in atherosclerosis.Sergin I, Evans TD, Razani B. Current Opinion in Lipidology, 2015. Oct;26(5):394-404.

7) Applications and Advances of Metabolite Biosensors for Metabolic Engineering. Liu D, Evans T, Zhang F. Metabolic Engineering, 2015. Sep;31:35-43.

8) Hypoxia in plaque macrophages: a new danger signal for interleukin-1β activation? Sergin I, Evans TD, Bhattacharya S, Razani B. Circulation Research, 115(10):817-20, 2014.

Last Updated: 6/13/2017 12:32:41 PM

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