Division of Biology and Biomedical Sciences MSC 8226-13-04 660 S. Euclid Ave. St. Louis, MO 63110-1093
Falmouth, MA
Harvard University (2015)
Molecular Genetics and Genomics
Daniel C. Link, MD
The Role of Ribosomal Stress in the Pathogenesis of T-cell Acute Lymphoblastic Leukemia
kjohansson@wustl.edu
I work in the lab of Dr. Daniel Link, in the Oncology Division, Section of Stem Cell Biology. We aim to understand the regulation of hematopoiesis, and to elucidate the molecular pathogenesis of hematologic malignancies for translational application. My current research projects focus on the aggressive hematologic malignancy T-cell Acute Lymphoblastic Leukemia. Through use of patient-derived xenograft models, flow cytometry, live-cell imaging, CRISPR-Cas9 editing , and molecular phenotyping, I hope to elucidate both the contribution of particular stress responses to T-ALL pathogenesis and to explore the cellular mechanism of a potentially synergistic chemotherapeutic combination.
Last Updated: 9/17/2019 5:23:58 PM
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