Division of Biology and Biomedical Sciences MSC 8226-13-04 660 S. Euclid Ave. St. Louis, MO 63110-1093
Boulder, CO
Brown University (2016)
Molecular Genetics and Genomics
Benjamin D. Humphreys, MD, PhD
Gene regulation in proximal tubule sub-types in chronic kidney disease
nicolas.ledru@wustl.edu
In the Humphreys lab, we use single cell sequencing techniques to study a proximal tubule subpopulation that appears to drive progressive damage and kidney disease. This population has been studied following acute kidney injury (AKI) and is associated with failure to recover and subsequent transition to chronic kidney disease (CKD). I am exploring this subpopulation’s presence and activity in kidneys that have not experienced AKI and whether it can drive CKD progression in other non-acute modes of kidney injury
Last Updated: 8/4/2022 11:34:51 AM
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