Division of Biology and Biomedical Sciences MSC 8226-13-04 660 S. Euclid Ave. St. Louis, MO 63110-1093
Lagos, Nigeria
New York Institute of Technology (2016)
Molecular Genetics and Genomics
Gregory D. Longmore, MD
Improving response to immunotherapy in High Grade Serous Ovarian Cancer
I am in the lab of Dr. Katherine Fuh. My PhD aims are: Aim 1: Identify molecular targets that mediate chemotherapeutic response to neoadjuvant and adjuvant therapy in patients with advanced high grade serous ovarian cancer.Aim 2: Elucidate the role of the DDR2 tyrosine kinase in immunotherapeutic response and decipher molecular pathways involved in synergistic interaction between DDR2 and checkpoint inhibitors like anti-PD1 and anti-CTLA4Aim 3: Determine how paclitaxel and AXL inhibition promotes tumor-associated macrophage polarization and affects other immune subpopulations such as T cell, NK cells, and dendritic cells
Last Updated: 8/4/2022 11:21:22 AM
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