Research Abstract:
Research in my laboratory is focused on the causes of individual differences in personality development and the genetic epidemiology of psychiatric disorders. The goal is to integrate psychometric, developmental and neurogenetic analyses of complex phenotypes related to health and disorder in the general population and in families. Current work involves longitudinal and family studies of normal and abnormal personality, alcoholism, schizophrenia and related traits. The relations of personality to psychopathology are being studied in terms of the non-linear dynamics of complex adaptive systems. Quantitative genetic analysis is conducted to characterize the transmission of psychiatric disorders. Genome screens and candidate gene analysis are underway for schizophrenia, alcoholism and personality traits.
Selected Publications:
Cloninger, C. Robert. Feeling good: The science of well-being. New York: Oxford University Press; 2004. 374 p.
Cloninger, C. Robert. The discovery of susceptibility genes for mental disorders. Proc Natl Acad Sci USA 2002 99(21):13365-13367.
Cloninger CR. Biology of personality dimensions. Curr Opin Psychiatry 2000 13:611-616.
Cloninger CR, Svrakic DM, Przybeck TR. A psychobiological model of temperament and character. Arch Gen Psychiatry 1993 50:975-990.
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