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| Dana R. Abendschein, Ph.D. - Role of coaagulation proteases and inflammatory molecules in vascular remodeling. |
| Yousef Abu-Amer, Ph.D. - Cellular and molecular mechanisms in osteoclasts; TNF signaling in inflammatory bone disease. |
| Joseph J.H. Ackerman, Ph.D. - Magnetic resonance spectroscopy and imaging of intact functioning biological systems. |
| Usha P. Andley, Ph.D. - Small heat shock protein functions in ocular systems and stress. |
| Jeffrey M. Arbeit, M.D. - Molecular regulation of epithelial carcinogenesis. |
| Jacques U. Baenziger, M.D., Ph.D. - Synthesis and function of unique carbohydrate structures as information-bearing macromolecules. |
| Nancy L. Baenziger, Ph.D. - Bradykinin/Histamine receptor regulation, signal transduction, phosphorylation, and hyperactivity in Alzheimer’s disease. |
| Thomas J. Baranski, M.D., Ph.D. - Signal transduction mechanisms by hormone receptors and G proteins. |
| Steven Bassnett, Ph.D. - Cell and molecular biology of the ocular lens. |
| Roger N. Beachy, Ph.D. - Molecular and cellular basis of virus infection: Control via biotechnology. |
| David C. Beebe, Ph.D. - Growth factors in eye development; role of oxygen in cataract and glaucoma |
| Carlos Bernal-Mizrachi, M.D. - Novel mechanisms of cardiovascular disease in human and mouse models with insulin resistance and type 2 DM. |
| Monica Bessler, M.D., Ph.D. - We investigate the molecular and biochemical pathways causing bone marrow failure and screen for new therapeutic agents that might improve the production of blood cells |
| Deepta Bhattacharya, Ph.D. - Fate Decisions in the Hematopoietic and Immune System |
| Kendall J. Blumer, Ph.D. - Signal transduction in the cardiovascular, nervous and visual systems. |
| Irving Boime, Ph.D. - Placental and pituitary hormone genes. |
| Ron Bose, M.D., Ph.D. - Proteomic studies of signal transduction pathways in breast cancer. |
| Walter A. Boyle, III, M.D. - Molecular and cellular actions of anesthetics and septic stimuli on vascular tissue. |
| Paul C. Bridgman, Ph.D. - Cell biology of developing nerve and muscle cells. |
| Steven Brody, M.D. - Abnormalities of the airway epithelial cell differentiation that characterize many lung diseases |
| Guojun Bu, Ph.D. - Receptor biology focusing on endocytosis, intracellular protein trafficking and signaling, and related human pathobiology |
| Peter M.J. Burgers, Ph.D. - Molecular Biology of DNA replication and repair in yeast. |
| Valeria Cavalli, Ph.D. - Axonal Transport, Injury Signaling and Nerve Regeneration. |
| Emily Cheng, M.D., Ph.D. - Integration of apoptotic signaling cascades and the mitochondrion-sependent death program. |
| Kyunghee Choi, Ph.D. - Hematopoietic, Vascular and Cardiac Development in Mammalian System |
| Richard A. Chole, M.D., Ph.D. - Role of Pseudomonas aeruginosa biofilms in cholesteatoma. |
| Roberto Civitelli, M.D. - Connexins, cadherins and beta-catenin in bone cell function. |
| John A. Cooper, M.D., Ph.D. - Molecular mechanisms of cell motility and cytoskeleton assembly. |
| Peter A. Crawford, M.D., Ph.D. - Integrating systemic metabolism into mammalian myocardial energetic homeostasis |
| Erika C. Crouch, Ph.D., M.D. - Structure and function of surfactant protein D (SP-D). |
| Nicholas O. Davidson, M.D. - Mammalian gene expression: Regulation through mRNA editing and RNA stabilization. |
| Marc I. Diamond, M.D. - |
| Ram Dixit, Ph.D. - Molecular mechanisms of cytoskeleton organization and function |
| Tamara L. Doering, M.D., Ph.D. - Investigations of capsule synthesis in the pathogenic fungus Cryptococcus neoformans. |
| Gerald W. Dorn, II, M.D. - The multiple biochemical signaling pathways for growth and death of heart cells |
| Susan K. Dutcher, Ph.D. - Cilia, cytokinesis, tubulin superfamily, microtubules, cell division, obesity, ciliary signaling. |
| Igor R. Efimov, Ph.D. - Cardiac arrhythmia mechanisms, imaging, implantable devices, tissue engineering |
| Elliot L. Elson, Ph.D. - Mechanical properties of reconstituted tissues. Fluctuation spectroscopy of protein interactions. |
| Roberta Faccio, Ph.D. - osteoclasts, arthritis, inflammation, phospholipase gamma, bone resorption, cytoskeleton |
| Thomas A. Ferguson, Ph.D. - Cell death, apoptosis, immune tolerance, T-cells, lymphocyte, macrophages, angiogenesis, immune privilege. |
| Thomas W. Ferkol, M.D. - The development of cell and animal models to study cystic fibrosis. |
| Simon J. Fisher, Ph.D., M.D. - Role of nutritional and hormonal brain signaling in pathogenesis of obesity, diabetes, and impaired hypoglycemic counterregulation. |
| Timothy P. Fleming, Ph.D. - Isolation and characterization of cancer-related genes. |
| William A. Frazier, Ph.D. - Thrombospondin-1/CD47 regulation of mitochondria, nitric oxide and cardiovascular function |
| Carl Frieden, Ph.D. - Protein aggregation processes |
| N. Gautam, Ph.D. - Imaging signaling in living cells. |
| Robert W. Gereau, Ph.D. - Cellular and molecular mechanisms of chronic pain. |
| Jeffrey M. Gidday, Ph.D. - Endogenous mechanisms of vascular and parenchymal cell protection in CNS ischemia |
| Daniel E. Goldberg, M.D., Ph.D. - Biochemistry of malaria. |
| Susana Gonzalo, Ph.D. - Mechanisms regulating nuclear architecture, chromatin structure, and telomere biology and their impact on chromosome stability, tumorigenesis and radiosensitivity |
| Jeffrey I. Gordon, M.D. - Genomic and metabolic foundations of symbiotic host-microbial relationships in the mammalian gut |
| Gregory A. Grant, Ph.D. - Relationship of structure to function in allosteric control mechanisms. |
| Timothy A. Graubert, M.D. - The study of normal and leukemic hematopoietic stem cell biology. |
| Richard W. Gross, M.D., Ph.D. - The molecular mechanisms through which biologic membranes participate in cellular activation processes. |
| David H. Gutmann, M.D., Ph.D. - Using mouse models to understand normal growth control and tumor formation in the mammalian brain. |
| Dennis E. Hallahan, M.D. - The mechanisms of cell death in normal tissues during cancer therapy |
| Marc R. Hammerman, M.D. - Transplantation of developing organs. |
| Daniel F. Hanson, Ph.D. - Fever as an evolutionarily adaptive regulator of immune host defense. |
| Phyllis I. Hanson, M.D., Ph.D. - Regulation of membrane trafficking |
| J. William Harbour, M.D. - Role of developmental and cell cycle genes in cancer. |
| Elizabeth S. Haswell, Ph.D. - Mechanotransduction in plants. |
| Erik D. Herzog, Ph.D. - Cellular and molecular analysis of circadian behavior in mammals. |
| John E. Heuser, M.D. - Electron microscopy of cells and molecules. |
| Didier Hodzic, Ph.D. - Role of LINC complexes (Linkers of the Nucleoskeleton to the Cytoskeleton) in nucleokinesis and neuronal migration |
| David M. Holtzman, M.D. - Cellular/Molecular/Biomarkers studies of Alzheimer’s disease and neonatal brain injury. |
| Michael J. Holtzman, M.D. - Acute and chronic responses to respiratory viruses. |
| Keith A. Hruska, M.D. - Mechanisms and treatment of CKD and complications, renal osteodystrophy and vascular clacification. |
| Paul W. Hruz, Ph.D., M.D. - Structural Biology and Regulation of Glucose Transport; Molecular Mechanisms Leading to Insulin Resistance |
| James J. Hsieh, M.D., Ph.D. - Integrate development, cancer, and stem cell through a common proteolytic framework |
| Yina H. Huang, Ph.D. - IP4 regulation of lymphocyte activation, development and tumorigenesis. |
| Andrew J.W. Huang, M.D., M.P.H. - Corneal epithelial wound healing, neovascularization and stromal dystrophies |
| James "Jim" E. Huettner, Ph.D. - Glutamate receptors, synaptic transmission and stem cell differentiation. |
| Scott J. Hultgren, Ph.D. - Pilus and amyloid fiber formation in bacteria: Structure, function and role in diseases of the urinary tract. |
| Shin-ichiro Imai, M.D., Ph.D. - Understanding the molecular mechanism of aging and longevity in mammals. |
| Stephen L. Johnson, Ph.D. - Growth control of adult stem cells and regeneration. |
| Daniel Kerschensteiner, M.D. - |
| Raphael Kopan, Ph.D. - Studies of cell fate determination in mammalian system with focus on Notch mediated signal transduction. |
| S. Kerry Kornfeld, M.D., Ph.D. - Signal transduction and cell fate specification during development. Aging. |
| Stuart A. Kornfeld, M.D. - Intracellular protein trafficking, including targeting of acid hydrolases to lysosomes. |
| Paul T. Kotzbauer, M.D., Ph.D. - Mechanisms of neurodegeneration in Parkinson's disease and related disorders. |
| Kristen Kroll, Ph.D. - Transcriptional regulation of neural cell fate, proliferation, and differentiation in embryos and embryonic stem cells. |
| Petra Anne Levin, Ph.D. - Temporal and spatial regulation of bacterial cell division. |
| Ellen Li, M.D., Ph.D. - Translational research in inflammatory bowel disease |
| Daniel C. Link, M.D. - Molecular regulation of normal and neoplastic hematopoiesis. |
| Jennifer K. Lodge, Ph.D. - Signal transduction, cell wall biosynthesis and resistance to oxidative and nitrosative stresses in the pathogenic fungus, Cryptococcus neoformans |
| Fanxin Long, Ph.D. - Developmental and regenerative biology of the mammalian skeleton |
| Gregory D. Longmore, M.D. - Epithelia morphogenesis in development and disease - cancer metastasis |
| Michael Lovett, Ph.D. - Human genetic diseases, genome technologies, systems biology, functional genomics of hearing loss and craniofacial development. |
| Peter D. Lukasiewicz, Ph.D. - Synaptic function and retinal neurobiology. |
| Liang Ma, Ph.D. - Understanding genetic pathways regulating epithelial differentiation. |
| Elaine M. Majerus, M.D., Ph.D. - Studies of factors involved in pro-thrombotic conditions. |
| Philip W. Majerus, M.D. - Mechanisms of intracellular signalling through phosphorylation of inositols and proteins. |
| Michael L. McDaniel, Ph.D. - Growth and proliferation of pancreatic islets in Types 1 & 2 diabetes. |
| Robert P. Mecham, Ph.D. - Cell-matrix interactions, extracellular matrix and development, vascular development and disease. |
| Steven J. Mennerick, Ph.D. - Physiology of glutamate and GABA neurotransmission in the CNS. |
| Robert W. Mercer, Ph.D. - Molecular and cell biology of ion pumps and transporters in plasma membrane; cell polarity. |
| Loren Scott Michel, M.D., MBA - Mechanisms of genomic instability and tumor progression |
| James G. Miller, Ph.D. - Ultrasonic investigation of the viscoelastic properties of cardiovascular tissue and bone |
| Kathryn G. Miller, Ph.D. - Function of actin-binding proteins in development. |
| Jason C. Mills, M.D., Ph.D. - Developmental, molecular, and cellular biology of gastric epithelial stem cells |
| Jeffrey H. Miner, Ph.D. - Genetic analyses of mouse organogenesis. |
| Stanley Misler, M.D., Ph.D. - Electrophysiological approaches to stimulus-secretion coupling in endocrine cells and neurons. |
| Kelle H. Moley, M.D. - Murine preimplantation embryogenesis: the effects of maternal hyperglycemia and hyperinsulinemia on glucose transporter and blastocyst survival. |
| Aubrey R. Morrison, M.B.B.S. - RNA-binding proteins in mRNA stability and cancer biology. |
| Michael Mueckler, Ph.D. - Molecular biology of glucose transporters. |
| Kenneth M. Murphy, M.D., Ph.D. - T cell development, lineage commitment. |
| Anthony J. Muslin, M.D. - Growth factor signal transduction in vertebrate embryonic development and cardiovascular disease. |
| Jeanne M. Nerbonne, Ph.D. - Molecular determinants of ion channel expression, distribution and functioning |
| Colin G. Nichols, Ph.D. - Ion channel biology in health and disease |
| Deborah J. Novack, M.D., Ph.D. - Role of NF-KB signalling in osteoclasts. |
| David M. Ornitz, Ph.D., M.D. - Growth factor signaling in lung, skeletal, cardiovascular and CNS development and physiology; Otopetrin in vestibular mechanosensory development |
| Daniel S. Ory, M.D. - Study of regulation of cholesterol homeostasis, and role of cholesterol in atherosclerosis and neurodegeneration. |
| Philip Osdoby, Ph.D. - Bone remodeling cell and molecular events of osteoclast activity and development. |
| Karen L. O`Malley, Ph.D. - Mechanisms underlying the specification, regulation, and neurodegeneration of dopaminergic and glutamatergic systems. |
| Tej K. Pandita, Ph.D. - Identification and characterization of tumor cells specific targets for radiosensitization. |
| M. Alan Permutt, M.D. - Pancreatic islet cell genes and diabetes genetics research. |
| Linda J. Pike, Ph.D. - EGF receptor-mediated cell signaling and the control of cell growth |
| David R. Piwnica-Worms, M.D., Ph.D. - Molecular imaging of gene expression and protein function in vivo; multidrug resistance transporters; metallopharmaceuticals. |
| Helen M. Piwnica-Worms, Ph.D. - Cell cycle and checkpoint control. |
| Kenneth S. Polonsky, M.D. - Role of pancreatic beta cell in the development of diabetes. |
| Ralph S. Quatrano, Ph.D. - Mechanisms in establishing cell polarity and regulatory gene expression in plants. |
| Keith M. Rich, M.D. - Influence of trophic factors on neuronal dead and axonal regeneration. |
| Joseph L. Roti Roti, Ph.D. - Cell-cycle progression and response of the cells to ionizing radiation and heat shock. |
| Joshua B. Rubin, M.D., Ph.D. - Investigating the basis of CXCL12 actions in development and cancer. |
| John H. Russell, Ph.D. - CNS/lymphocyte interactions regulating inflammation and pathogenesis in a mouse model of multiple sclerosis |
| J. Evan Sadler, M.D., Ph.D. - Biochemistry and function of hemostatic proteases and von Willebrand factor. |
| Shelly Sakiyama-Elbert, Ph.D. - My research focuses on the delivery of protein growth factors to promote tissue regeneration. |
| Lawrence B. Salkoff, Ph.D. - How ion channels function in physiology and behavior. |
| Linda J. Sandell, Ph.D. - Gene regulation of extracellular matrix proteins and its influence on the phenotype of cells |
| Mark S. Sands, Ph.D. - Pathophysiology and novel therapies for lysosomal storage diseases. |
| Jean E. Schaffer, M.D. - Cellular responses to metabolic stress. |
| Paul Schlesinger, M.D., Ph.D. - Intracellular ion transport, chloride, protons, mitochondrial channels, phagosome, parasites. |
| Alan L. Schwartz, Ph.D., M.D. - Receptor-mediated protein targeting and protein degradation. |
| Robert M. Senior, M.D. - Mechanisms of lung remodeling during development and lung diseases. |
| Andrey S. Shaw, M.D. - Biochemistry and imaging of signaling pathways and genetic basis of kidney disease. |
| Philip D. Stahl, Ph.D. - Hominoid-specific genes such as TBC1D3, that regulate growth factor receptor signaling, may explain why human physiology and pathobiology differs from lower species. |
| Thaddeus S. Stappenbeck, Ph.D., M.D. - Molecular interactions between intestinal epithelial stem cells and their niche. |
| Joe Henry Steinbach, Ph.D. - Function and regulation of transmitter-gated membrane channels. |
| Thomas H. Steinberg, M.D. - Gap junctional communication, P2 receptors, and intercellular calcium signaling. |
| William Stenson, M.D. - We are interested in the epithelial response to injury in the intestine and in mucosal immununology in the intestine. |
| Sheila A. Stewart, Ph.D. - Telomere biology in human cancer and aging. |
| John-Stephen Taylor, Ph.D. - Structure-activity relationships in UV mutagenesis; nucleic acid-based chemotherapeutic and imaging agents |
| Steven L. Teitelbaum, M.D. - Molecular mechanisms of osteoclast differentiation and bone resorption. |
| Robert E. Thach, Ph.D. - Ecology of vector-borne diseases. |
| Douglas M. Tollefsen, M.D., Ph.D. - Biochemistry and physiology of protease inhibitors that regulate blood coagulation. |
| Michael Tomasson, M.D. - Chromosomal translocations, fusion oncogenes, and the molecular pathogenesis of leukemia. |
| Dwight A. Towler, M.D., Ph.D. - Regulation of vascular calcification and vascular mesenchymal cell fate. |
| Heather L. True-Krob, Ph.D. - Epigenetic regulation of phenotypes by propagation of prions in yeast |
| John W. Turk, M.D., Ph.D. - Phospholipid-derived mediators and insulin secretion. |
| Zsolt Urban, Ph.D. - Human genetic diseases of the elastic fiber system. |
| Joseph P. Vogel, Ph.D. - Intracellular replication of Legionella pneumophila inside macrophages. |
| Jason D. Weber, Ph.D. - Role of tumor suppressors and oncogenes in growth control. |
| Conrad C. Weihl, M.D., Ph.D. - The interplay between the ubiquitin-proteasome and autophagy pathways in skeletal muscle and neurodegenerative disorders. |
| Katherine N. Weilbaecher, M.D. - Molecular mechanisms through which tumor cells metastasize to bone. |
| Samuel A. Wickline, M.D. - Molecular imaging and targeted therapeutics with nanobiotechnology. |
| Robert S. Wilkinson, Ph.D. - Synaptic structure and function, particularly vesicle processing pathways. |
| Richard K. Wilson, Ph.D. - Genomic studies of C. elegans, yeast and humans. |
| Qin Yang, M.D., Ph.D. - Telomere recombination and maintenance, AKT oncogenic signaling |
| Nabeel R. Yaseen, M.D., Ph.D. - Molecular Pathogenesis of Acute Myeloid Leukemia |
| Zhongsheng You, Ph.D. - Molecular mechanisms of genome surveillance and tumorigenesis |
| Dong Yu, Ph.D. - Human cytomegalovirus replication and pathogenesis |
| Lijuan Zhang, Ph.D. - Glycosaminoglycan structure and biology |