Dennis L. Barbour, M.D., Ph.D.

Associate Professor
Biomedical Engineering
Neuroscience
Otolaryngology

Neurosciences Program

  • 314-935-7548

  • 314-935-5083

  • 314-935-7448

  • 1097

  • 200E Whitaker

  • dbarbour@biomed.wustl.edu

  • http://lsnn.wustl.edu

  • neurobiology, neurophysiology, hearing, sensation, perception, cognitive processing, human-computer interfaces

  • Sensation, perception and cognitive processing of sounds and speech

Research Abstract:

My research focuses on the encoding of sensory information in the brain and how neural circuits can be modified to improve that encoding. We are particularly interested in how complex sounds and speech are encoded in the brain when interfering noise is present. We also design software that can be used to diagnose hearing or auditory processing disorders and then improve hearing function through repeated use. This software takes the form of compelling mobile games that deliver auditory materials in novel ways. This software will ultimately make auditory testing and training available to the public through smartphones.

Selected Publications:

Killian NJ, Watkins PV, Davidson LS, Barbour DL. “The effects of auditory contrast tuning upon speech intelligibility.” Front Psychol, 7:1145, 2016.

Gardner JR, Malkomes G, Cunningham JP, Barbour DL, Garnett R. “Bayesian active model selection with an application to automated audiometry.” Adv Neural Inf Proc Sys, 2377-2385, 2015.

Gardner JR, Song XD, Cunningham JP, Barbour DL, Weinberger KQ. Psychophysical testing with Bayesian active learning. Uncer Art Intel 286-295, 2015

XD Song, Wallace BM, Gardner JR, Ledbetter NM, Weinberger KQ, Barbour DL. Fast, continuous audiogram estimation using machine learning. Ear and Hearing 36(6):e326-35, 2015

Sinha DB, Ledbetter NM, Barbour DL. Spike-timing computation properties of a feed-forward neural network model Front Comput Neurosci 8:5, 2014. PMID: 24478688.

Katta N, Chen TL, Watkins PV and Barbour DL. Evaluation of techniques used to estimate cortical feature maps. J Neurosci Meth 2011 202(1): 87-98.

Barbour DL. Intensity-invariant coding in the auditory system. Neurosci Biobehav Rev 2011 35(10): 2064-72.

Chen TL, Watkins PV and Barbour DL. Theoretical limitations on functional imaging resolution in auditory cortex. Brain Res 2010 1319: 175-89.

Watkins PV, Chen TL, Barbour DL. A computational framework for topographies of cortical areas. Biol Cybern. 2009 Mar;100(3): 231-48.

Watkins PV, Barbour DL. Specialized neuronal adaptation for preserving input sensitivity. Nat Neurosci. 2008 Nov;11(11): 1259-61.

Last Updated: 8/29/2016 9:41:50 AM

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