Kevin J. Black, M.D.

Professor
Psychiatry
Radiology
Neurology

Neurosciences Program

  • 314-362-5041

  • 314-362-5041

  • 314-362-0168

  • 8134

  • East Bldg., Rm 2106

  • kevin@wustl.edu

  • https://sites.wustl.edu/blacklab/

  • fMRI, neuroimaging, movement disorders, Tourette syndrome, pharmacology, PET, deep brain stimulation, DBS

  • (1) Tourette syndrome neuroimaging; (2) Parkinson disease pharmacological imaging; (3) mapping effects of deep brain stimulation (DBS)

Research Abstract:

My clinical interests focus on the interface between psychiatry and movement disorders. I am especially interested in the "pre-Tourette" period in children with tics, and in depression in Parkinson disease.

My imaging research is influenced by these clinical interests and is primarily focused on functional imaging of the dopaminergic system.

Specific projects, current and past, and my mentorship history, are summarized on the lab web page (https://sites.wustl.edu/blacklab/).

Selected Publications:

Gourisankar A, Eisenstein SA, Trapp NT, Koller JM, Campbell MC, Ushe M, Perlmutter JS, Hershey T, Black KJ (2018). Mapping movement, mood, motivation and mentation in the subthalamic nucleus. R Soc Open Sci 5:171177. PubMedCentral journal -- in process. DOI: 10.1098/rsos.171177.

*Greene DJ, *Williams AC III, Koller JM, Schlaggar BL, Black KJ, The Tourette Association of America Neuroimaging Consortium (2017). Brain structure in pediatric Tourette syndrome. Molecular Psychiatry 22(7):972-980. PubMed PMID: 27777415 PubMedCentral PMCID: PMC5405013 DOI: 10.1038/mp.2016.194
*Equal contributors

Black KJ, Black ER, Greene DJ, Schlaggar BL (2016). Provisional Tic Disorder: what to tell parents when their child first starts ticcing. F1000Research 5:696. PubMed PMID: 27158458 PubMedCentral PMCID: PMC4850871 DOI: 10.12688/f1000research.8428.1

Koller JM, Vachon MJ, Bretthorst GL, Black KJ (2016 April). Rapid quantitative pharmacodynamic imaging with Bayesian estimation. Front Neurosci. 10: 144. PubMed PMID: 27092045 PubMedCentral PMCID: PMC4825616 DOI: 10.3389/fnins.2016.00144

Greene DJ, Church JA, Dosenbach NUF, Nielsen AN, Adeyemo B, Nardos B, Petersen SE, Black KJ, Schlaggar BL (2016). Multivariate pattern classification of pediatric Tourette syndrome using functional connectivity MRI. Dev Sci 19(4):581-598. PubMed PMID: 26834084 PubMedCentral PMCID: PMC4945470 DOI: 10.1111/desc.12407

Eisenstein SA, Koller JM, Black KD, Campbell MC, Lugar HM, Ushe M, Tabbal SD, Karimi M, Hershey T, Perlmutter JS, Black KJ (2014). Functional anatomy of subthalamic nucleus stimulation in Parkinson disease. Annals of Neurology 76(2): 279-295. PubMed PMID 24953991 PubMedCentral PMCID: PMC4172323 DOI: 10.1002/ana.24204

Black KJ, Koller JM, Campbell MC, Gusnard DA, Bandak SI (2010 Dec 1). Quantification of indirect pathway inhibition by the adenosine A2a antagonist SYN115 in Parkinson disease. Journal of Neuroscience 30(48): 16284-16292. PubMed PMID 21123574 PubMedCentral PMCID: PMC3008651 DOI: 10.1523/JNEUROSCI.2590-10.2010

Last Updated: 7/27/2018 11:16:59 AM

Weighted mean image (i), p-image (ii) and 3D p-image (iii) for measures with significant effect of contact location in the 3D analyses. (a) Body bradykinesia and hypokinesia item. (b) Rigidity. (c) Tremor at rest. Fig. 2 from Gourisankar et al, 2018.
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