Brad A. Racette, M.D.

Professor
Neurology

Neurosciences Program

Research Abstract:

My research laboratory focuses on the environmental epidemiology of Parkinson disease. The primary areas of research in our laboratory include a worksite based studies of parkinsonism in welders, motor and cognitive health effects associated with environmental Mn exposure, imaging biomarkers of parkinsonism in Mn exposed workers, neuropathology of chronic Mn exposure, and geographic information systems research into demographic and risk of Parkinson disease associated with solvent exposure.

Selected Publications:

Racette BA and Willis AW. Time to Change the Blind Men and the Elephant Approach to Parkinson Disease? Neurology 2015;85:190-196.

Criswell SR, Nelson G, Gonzalez-Cuyar LF, Huang J, Shimony JS, Checkoway H, Simpson CD, Dills R, Seixas NS, Racette BA.Ex vivo magnetic resonance imaging in South African manganese mine workers. Neurotoxicology 2015; 49:8-14.

Nielsen SS, Checkoway H, Criswell SR, Farin FM, Stapleton PL, Sheppard L, Racette BA. Inducible nitric oxide synthase gene methylation and parkinsonism in manganese-exposed welders. Parkinsonism Relat Disord 2015;21(4):355-60

Gonzalez-Cuyar LF, Nelson G, Criswell SR, Ho P, Lonzanida JA, Checkoway H, Seixas N, Gelman BB, Evanoff BA, Murray J, Zhang J, Racette BA. Quantitative neuropathology associated with chronic manganese exposure in South African mine workers. Neurotoxicology, 2014;45:260-6.

Racette BA, Criswell SC, Lundin JI, Hobson A, Seixas N, Kotzbauer PT, Evanoff BA, Perlmutter JS, Zhang J, Sheppard L, Checkoway H. Increased Risk of Parkinsonism Associated with Welding Exposure. Neurotoxicology 2012;33(5):1356-61.

Willis AW, Schootman M, Tran R, Kung N, Evanoff BA, Perlmutter JS, Racette BA. Neurologist Associated Reduction in PD Related Hospitalizations. Neurology 2012;79(17):1774-80.

Willis AW, Schootman M, Kung N, Evanoff BA, Perlmutter JS, Racette BA. Predictors of Survival in Parkinson Disease. Arch Neurol 2012; (5):601-7.

Criswell SR, Perlmutter JS, Videen TO, Moerlein SM, Flores HP, Birke AM, Racette BA. Reduced Uptake of [18F]FDOPA PET in Asymptomatic Welders with Occupational Manganese Exposure. Neurology 2011; 6(15):1296-301.

Willis AW, Evanoff, BA, Lian M, Wegrzyn A, Galarza A, Racette BA. Metal Emissions and Urban Incident Parkinson Disease: A Community Health Study of Medicare Beneficiaries Using Geographical Information Systems. Am J. Epi 2010; 172(12):1357-63.

Willis AW, Evanoff BA, Lian M, Criswell SR, Racette BA. Geographical and Ethnic Variation in PD: A Population-Based Study of U.S. Medicare Beneficiaries. Neuroepidemiology 2010;34:143-151.

Last Updated: 9/22/2015 10:35:22 AM

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