Ryan Bogdan, PhD

Associate Professor
Psychological and Brain Sciences

Neurosciences Program
Molecular Genetics and Genomics Program
Human and Statistical Genetics Program

  • 314-935-7957

  • 617-407-5645

  • Somers Family Hall 453B

  • rbogdan@wustl.edu

  • http://bogdanlab.com

  • How genetic variation and environmental experience contribute to individual differences in brain function, behavior, and psychopathology

Research Abstract:

Ryan Bogdan’s research examines how genetic variation and environmental experience contribute to individual differences in brain function, behavior, and psychopathology. He is particularly interested in understanding how differences emerge in reward and threat processing, as well as stress responsiveness, and the role of these factors in the development of depression and anxiety. He uses a variety of methods including molecular genetics, fMRI, EEG/ERP, pharmacologic challenge, twin studies, behavioral assessment, and self-report in both healthy and clinical populations.

Selected Publications:

Bogdan R, Agrawal A, Gaffrey MS, Tillman R & Luby JL. (in press). Serotonin transporter linked polymorphic region (5-HTTLPR) genotype and stressful life events interact to predict preschool-onset depression: A replication and developmental extension. Journal of Child Psychology and Psychiatry.

Lohoff FW, Hodge R, Narasimhan S, Nall A, Ferroro TN, Mickey BJ, Heitzeg MM, Langenecker SA, Zubieta J, Bogdan R, Nikolova YS, Drabant E, Hariri AR, Bevilacqua L, Goldman D, Doyle GA. (in press). Functional genetic variants in the vesicular monoamine transporter 1 (VMAT1) modulate emotion processing. Molecular Psychiatry.

Bogdan R, Hyde LW, Hariri AR. (2013). A neurogenetics approach to understanding individual differences in brain, behavior and risk for psychopathology. Molecular Psychiatry, 18, 288-299.

Bogdan R & Hariri AR. (2012). Neural embedding of stress reactivity. Nature Neuroscience, 15, 1605-1607.

Bogdan R, Nikolova YS, Pizzagalli DA. (2013). Neurogenetics of depression. Neurobiology of Disease, 52, 12-23.

White MG, Bogdan R, Fisher PM, Muoz K, Williamson DE & Hariri AR.(2012). FKBP5 and emotional neglect interact to predict individual differences in amygdala reactivity. Genes, Brain and Behavior, 11, 869-878.

Bogdan R, Williamson DE & Hariri AR. (2012). Mineralocorticoid recceptor iso/val genotype (rs5522) moderates the association between priori childhood emotional neglect and amygdala reactivity. American Journal of Psychiatry, 169, 515-522.

Bogdan R, Santesso DL, Fagerness J, Perlis RH & Pizzagalli DA. (2011). Corticotropin-releasing hormone receptor type 1 (CRHR1) genetic variation and stress interact to influence reward learning. Journal of Neuroscience, 31, 13110-13117.

30. Bogdan R & Pizzagalli DA. (2009). The heritability of hedonic capacity and perceived stress: A twin study evaluation of candidate depressive phenotypes. Psychological Medicine, 39, 211-218.

Bogdan R & Pizzagalli DA. (2006). Acute stress reduces reward responsiveness: Implications for depression. Biological Psychiatry, 60, 1147-1154.

Last Updated: 7/22/2013 10:42:28 AM

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