Siobhan Sutcliffe, Ph.D., Sc.M., M.H.S.

Associate Professor
Surgery
Public Health Sciences

Molecular Microbiology and Microbial Pathogenesis Program

  • 314-362-3788

  • 8100

  • sutcliffes@WUSTL.EDU

  • Infectious causes of cancer and chronic diseases

Research Abstract:

Research in the Sutcliffe lab focuses on infectious or inflammatory causes of prostate cancer and benign prostatic hyperplasia (BPH), including studies on the possible roles of gonorrhea, syphilis, Chlamydia trachomatis infection, Trichomonas vaginalis infection, human papillomavirus infection, human herpesvirus type 8 infection, and several other viral infections in prostate cancer and/or BPH development. Also examination of the possible role of Trichomonas vaginalis infection, a common sexually transmitted protozoan infection, in prostate cancer development; studies investigating the extent of prostate involvement during sexually transmitted infections; and studies examining the role of anti-inflammatory agents, such as aspirin, in BPH development.

Selected Publications:

Sutcliffe S, Alderete JF, Till C, Goodman PJ, Hsing AW, Zenilman JM, De Marzo AM and Platz EA. Trichomonosis and subsequent risk of prostate cancer in the Prostate Cancer Prevention Trial. Int J Cancer. 2009; 124(9):2082-7.

Sutcliffe S, Giovannucci E, Isaacs WB, Willett WC and Platz EA. Acne and risk of prostate cancer. Int J Cancer. 2007;121(12):2688-92.

Sutcliffe S, Rohrmann S, Giovannucci E, Nelson KE, De Marzo AM, Isaacs WB, Nelson WG and Platz EA. Viral infections and lower urinary tract symptoms in the Third National Health and Nutrition Examination Survey. J Urol. 2007;178(5):2181-5.

Sutcliffe S, Giovannucci E, Gaydos CA, Viscidi RP, Jenkins FJ, Zenilman JM, Jacobson LP, De Marzo AM, Willett WC and Platz EA. Plasma antibodies against Chlamydia trachomatis, human papillomavirus and human herpesvirus type 8 infection in relation to risk of prostate cancer: a prospective study. Cancer Epidemiol Biomarkers Prev. 2007;16(8):1573-80.

Sutcliffe S, Giovannucci E, Leitzmann MF, Rimm EB, Stampfer MJ, Willett WC and Platz EA. A prospective cohort study of red wine consumption and risk of prostate cancer. Int J Cancer. 2007;120(7):1529-35.

Last Updated: 7/21/2014 12:24:57 PM

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