• Carnegie Mellon University (2014)

  • Biochemistry, Biophysics, and Structural Biology

  • Daved H. Fremont, Ph.D.

  • Structural studies of host-pathogen interactions of alphaviruses

  • kbasore@wustl.edu

Graduate Publications:

Earnest JT, Holmes AC, Basore K, Mack M, Fremont DH, Diamond MS. 2021 The mechanistic basis of protection by non-neutralizing anti-alphavirus antibodies. Cell Rep, 35(1):108962.

Kim AS, Zimmerman O, Fox JM, Nelson CA, Basore K, Zhang R, Durnell L, Desai C, Bullock C, Deem SL, Oppenheimer J, Shapiro B, Wang T, Cherry S, Coyne CB, Handley SA, Landis MJ, Fremont DH, Diamond MS. 2020 An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis. Cell Host Microbe, 27(3):428-440.e9.

Holmes AC, Basore K, Fremont DH, Diamond MS. 2020 A molecular understanding of alphavirus entry. PLoS Pathog, 16(10):e1008876.

Ma H, Kim AS, Kafai NM, Earnest JT, Shah AP, Case JB, Basore K, Gilliland TC, Sun C, Nelson CA, Thackray LB, Klimstra WB, Fremont DH, Diamond MS. 2020 LDLRAD3 is a receptor for Venezuelan equine encephalitis virus. Nature, ():Online ahead of print.

Basore K, Kim AS, Nelson CA, Zhang R, Smith BK, Uranga C, Vang L, Cheng M, Gross ML, Smith J, Diamond MS, Fremont DH. 2019 Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor. Cell, ():pii: S0092-8674(19)30392-7.

Kim AS, Austin SK, Gardner CL, Zuiani A, Reed DS, Trobaugh DW, Sun C, Basore K, Williamson LE, Crowe JE Jr, Slifka MK, Fremont DH, Klimstra WB, Diamond MS. 2019 Protective antibodies against Eastern equine encephalitis virus bind to epitopes in domains A and B of the E2 glycoprotein. Nat Microbiol, 4(1):187-97.

Earnest JT, Basore K, Roy V, Bailey AL, Wang D, Alter G, Fremont DH, Diamond MS. 2019 Neutralizing antibodies against Mayaro virus require Fc effector functions for protective activity. J Exp Med, ():pii: jem.20190736.

Zhang R, Kim AS, Fox JM, Nair S, Basore K, Klimstra WB, Rimkunas R, Fong RH, Lin H, Poddar S, Crowe JE Jr, Doranz BJ, Fremont DH, Diamond MS. 2018 Mxra8 is a receptor for multiple arthritogenic alphaviruses. Nature, ():Epub ahead of print.

Last Updated: 7/24/2018 1:07:42 PM

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