• Clarion University (2016)

  • Neurosciences

  • Erik S. Musiek, M.D., Ph.D.

  • The bi-directional relationship between the circadian clock and Alzheimer's Disease.

  • pwsheehan@wustl.edu

Graduate Publications:

Basak JM, Ferreiro A, Cohen LS, Sheehan PW, Nadarajah CJ, Kanan MF, Sukhum KV, Dantas G, Musiek E. 2021 Bacterial sepsis increases hippocampal fibrillar amyloid plaque load and neuroinflammation in a mouse model of Alzheimer's disease. Neurobiol Dis, 152():105292.

Lee J, Kim DE, Griffin P, Sheehan PW, Kim DH, Musiek ES, Yoon SY. 2020 Inhibition of REV-ERBs stimulates microglial amyloid-beta clearance and reduces amyloid plaque deposition in the 5XFAD mouse model of Alzheimer's disease. Aging Cell, 19(2):e13078.

Sheehan PW, Musiek ES. 2020 Evaluating Circadian Dysfunction in Mouse Models of Alzheimer's Disease: Where Do We Stand?. Front Neurosci, 14():703.

Griffin P, Sheehan PW, Dimitry JM, Guo C, Kanan MF, Lee J, Zhang J, Musiek ES. 2020 REV-ERBα mediates complement expression and diurnal regulation of microglial synaptic phagocytosis. Elife, ():9:e58765.

Griffin P, Dimitry JM, Sheehan PW, Lananna BV, Guo C, Robinette ML, Hayes ME, Cedeño MR, Nadarajah CJ, Ezerskiy LA, Colonna M, Zhang J, Bauer AQ, Burris TP, Musiek ES. 2019 Circadian clock protein Rev-erbα regulates neuroinflammation. Proc Natl Acad Sci USA, 116(11):5102-07.

Patel TK, Habimana-Griffin L, Gao X, Xu B, Achilefu S, Alitalo K, McKee CA, Sheehan PW, Musiek ES, Xiong C, Coble D, Holtzman DM. 2019 Dural lymphatics regulate clearance of extracellular tau from the CNS. Mol Neurodegener, 14(1):11.

Lananna BV, Nadarajah CJ, Izumo M, Cedeño MR, Xiong DD, Dimitry J, Tso CF, McKee CA, Griffin P, Sheehan PW, Haspel JA, Barres BA, Liddelow SA, Takahashi JS, Karatsoreos IN, Musiek ES. 2018 Cell-Autonomous Regulation of Astrocyte Activation by the Circadian Clock Protein BMAL1. Cell Rep, 25(1):1-9.e5.

Last Updated: 6/22/2017 11:42:32 AM

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