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Yousef Abu-Amer, Ph.D.
- Investigating molecular mechanisms underlying inflammation-induced degenerative skeletal diseases including joint degeneration, inflammatory arthritis and osteolysis
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Nada A. Abumrad, Ph.D.
- Fatty acids regulate energy balance and tissue renewal. Dysfunction of this regulation causes disease
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Gustav Akk, Ph.D.
- Function and modulation of transmitter-gated ion channels
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Ream Al-Hasani, Ph.D.
- Understanding the endogenous opioid systems to defeat addiction, ameliorate affective disorders, and relieve chronic pain.
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Ghazaleh Ashrafi, Ph.D.
- Uncovering novel regulators of glycolytic and mitochondrial metabolism at the synapse and their role in the pathology of Alzheimer’s disease
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Monika Bambouskova, Ph.D.
- Immunometabolism - metabolic regulation of immune cell activation
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Thomas J. Baranski, M.D., Ph.D.
- Signal transduction by G proteins and pathogenesis of diabetes
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David L. Bark, Ph.D.
- Applying biomechanics and mechanobiology (the interaction and response of cells and tissue to mechanical forces) to diagnose, study, and treat various forms of cardiovascular disease.
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Steven Bassnett, Ph.D.
- Ocular cell biology
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Luis F.Z. Batista, Ph.D.
- Understanding the role of DNA damage and RNA degradation during tissue homeostasis, regeneration, aging, and cancer
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Jeffrey J. Bednarski II, M.D., Ph.D.
- Understanding the signals that direct early B cell development
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Carmen Bergom, M.D., Ph.D.
- Identification of new targets to improve tumor radiation effectiveness and to protect normal tissues such as the heart from radiation injury
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Carlos Bernal-Mizrachi, M.D.
- Novel mechanisms of cardiovascular disease in human and mouse models with insulin resistance and type 2 DM
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Matthew R. Bersi, Ph.D.
- Our research is focused on soft tissue biomechanics and mechanobiology
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Kendall J. Blumer, Ph.D.
- Tumor cell biology, signal transduction, and drug development
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Irving Boime, Ph.D.
- Placental and pituitary hormone genes
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Ron Bose, M.D., Ph.D.
- Genomics and Cell Signaling in Breast Cancer
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Jonathan R. Brestoff, M.D., Ph.D., MPH.
- Understanding how immune cells and metabolic organs interact to maintain normal metabolism and to support adaptation to physiologic challenges
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Paul C. Bridgman, Ph.D.
- Cell biology of developing nerve and muscle cells
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Steven Brody, M.D.
- Molecular and genetic mechanisms of airway epithelial cell differentiation and ciliogenesis
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Peter M.J. Burgers, Ph.D.
- Molecular Biology of DNA replication and damage response in yeast and human
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Valeria Cavalli, Ph.D.
- Cellular, Molecular and Epigenetic control of axon regeneration
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Grant Challen, Ph.D.
- Understanding the genetic and epigenetic mechanisms that regulate normal and leukemic stem cells
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Tao Che, Ph.D.
- Characterizing and dissecting the molecular mechanisms of opioid receptor signaling
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Hong Chen, Ph.D.
- Combines biology, engineering, and medicine to develop ultrasound techniques for noninvasive, targeted, and personalized cancer treatment
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Yao Chen, Ph.D.
- Understanding the function of neuromodulators and sleep through the spatiotemporal dynamics of molecular signals
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Ying Maggie Chen, M.D., Ph.D.
- Understanding the molecular mechanisms of primary nephrotic syndrome (NS)
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Wayland W. L. Cheng, M.D., Ph.D.
- I am interested in the structure and function of neuronal ligand-gated ion channels, and the mechanism of channel modulation by endogenous lipids or exogenous drugs such as general anesthetics.
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Jaehyung (Gus) Cho, Ph.D.
- Understanding the mechanism mediating intravascular cell-cell interactions and vascular occlusion under thromboinflammatory conditions, including thrombosis, ischemia/reperfusion injury, and sickle cell disease
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Jaebok Choi, Ph.D.
- Understanding T cells and immunoregulatory networks in GvHD and GvL for the treatment of hematopoietic malignancies.
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Kyunghee Choi, Ph.D.
- Angioimmune interface in development, tissue regeneration, and cancer
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Matt Christopher, M.D., Ph.D.
- Improve outcomes for patients with acute myeloid leukemia (AML) and other hematopoietic malignancies utilizing genomic and molecular biology techniques
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Roberto Civitelli, M.D.
- Connexins, cadherins in bone cell interactions with cancer and energy metabolism
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Regina Clemens, M.D., Ph.D.
- The mechanisms regulating calcium-dependent neutrophil activation
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Clair Crewe, Ph.D.
- Understanding extracellular vesicle (EV)-mediated signaling during homeostatic and pathologic metabolic regulation
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Erika C. Crouch, Ph.D., M.D.
- Structure and function of surfactant protein D (SP-D)
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Nicholas O. Davidson, M.D.
- Mammalian gene expression: Regulation through mRNA editing and RNA stabilization
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Gus Davis, M.D., Ph.D.
- Understanding the molecular and cellular mechanisms of protein aggregation and neurodegeneration in Parkinson disease and dementia with Lewy bodies
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Brian J. DeBosch, M.D., Ph.D.
- To elucidate gut and hepatic determinants of metabolic disease, including diabetes mellitus, metabolic syndrome and their complications
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David G. DeNardo, Ph.D.
- Molecular Mechanisms of Immune Regulation of Tumor Progression.
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Carl DeSelm, M.D., Ph.D.
- Dr. DeSelm clinically focuses on treating lymphoma, and is actively developing novel CAR T cell approaches to treating solid tumors, including lymphoma, pancreatic cancer and glioblastoma.
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Jorge Di Paola, M.D.
- The genetics of bleeding and thrombotic disorders and mechanisms of platelet activation
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Mary C. Dinauer, M.D., Ph.D.
- Role of leukocyte NADPH oxidase in innate immunity, inflammation, and autoimmunity
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Siyuan Ding, Ph.D.
- Understanding how rotavirus (RV), an important enteric viral pathogen, interacts with the host innate immune system in the small intestine
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Abhinav Diwan, MD, FACC, FAHA
- Transcriptional regulation of lysosome machinery under stress
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Ram Dixit, Ph.D.
- Molecular mechanisms of cytoskeleton organization and function
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Sergej Djuranovic, Ph.D.
- Molecular mechanisms of translational control
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Tamara L. Doering, M.D., Ph.D.
- Biology and pathogenesis of the pathogenic fungus Cryptococcus neoformans
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Gerald W. Dorn, II, M.D.
- Cellular, Molecular, And Genetic Studies Of Cardiac Hypertrophy And Heart Failure
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Susan K. Dutcher, Ph.D.
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Elliot L. Elson, Ph.D.
- Mechanical properties of reconstituted tissues; fluctuation spectroscopy of protein interactions
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Sarah England, Ph.D.
- Molecular mechanisms underlying uterine function during pregnancy
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Roberta Faccio, Ph.D.
- interactions between bone and immune cells in inflammation and cancer
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Thomas A. Ferguson, Ph.D.
- We are examining the role of the autophagy pathway in the function of the retina and its role in diseases of the eye
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Francesca Ferraro, M.D., Ph.D.
- We use both mouse models and patient samples of acute myloid leukemia to understand leukemogenesis and to identify novel therapeutic targets.
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Brian N. Finck, Ph.D.
- Identify novel target pathways for therapeutic treatment of obesity-related diseases including diabetes, cardiovascular disease, and fatty liver disease
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Antonina Frolova, M.D., Ph.D.
- Improve obstetric outcomes for women and their neonates by understanding and targeting mechanisms of dysfunctional uterine contractility
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Harrison W. Gabel, Ph.D.
- Exploration of functions for neuron-specific regulators of gene expression, leveraging genes and mechanisms implicated in human neurologic disease to point us toward critical pathways in the brain.
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Gilbert Gallardo, Ph.D.
- Understand the molecular mechanisms that regulate reactive astrocytes and their neurotoxicity in
neurodegenerative diseases, including Alzheimer’s disease, by utilizing a combination of biochemistry, molecular biology, cellular models of inflammation and mouse models of neurodegenerative diseases.
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Robert W. Gereau, Ph.D.
- Cellular and molecular mechanisms of chronic pain, preclinical and translational research
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Leslie Gewin, M.D.
- Mechanisms of chronic kidney disease progression, treatment options to halt kidney disease progression
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Daniel E. Goldberg, M.D., Ph.D.
- Biochemistry of malaria
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Dennis Goldfarb, Ph.D.
- Computational mass spectrometry, proteomics, and their applications in biology
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Matthew L. Goodwin, M.D., Ph.D.
- Metabolism of cancer, targeting tumor metabolism by blocking metabolic pathways
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Jeffrey I. Gordon, M.D.
- Role of the human gut microbiome in health and disease, notably childhood undernutrition and obesity
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Gregory A. Grant, Ph.D.
- Relationship of structure to function in allosteric control mechanisms
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Abby M. Green, MD
- The etiology of mutagenesis and genome instability in pediatric cancers
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Michael J. Greenberg, Ph.D.
- The Greenberg lab seeks to understand the molecular and cellular biophysics of heart disease, with the goal of engineering disease models and precision therapeutics
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Obi L. Griffith, Ph.D.
- Development of personalized medicine strategies for cancer using genomic technologies
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Richard W. Gross, M.D., Ph.D.
- The molecular mechanisms through which biologic membranes participate in cellular activation processes
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Farshid Guilak, Ph.D.
- Focuses on the role of biomechanical factors in the onset, progression, and treatment of osteoarthritis and other joint diseases.
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Carmen Halabi, M.D., Ph.D.
- Understanding how the extracellular matrix (ECM) contributes to normal arterial development and how its disruptionleads to abnormal vascular development and disease
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Dennis E. Hallahan, M.D.
- The mechanisms of cell death in normal tissues during cancer therapy
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Jeffrey Haspel, M.D., Ph.D.
- Understand the impact of time as a biological variable in the development of critical illness such as sepsis, respiratory failure and chronic inflammatory lung disease
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Elizabeth S. Haswell, Ph.D.
- Mechanobiology with a focus on mechanosensitive ion channels
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Jason M. Held, Ph.D.
- Redox biochemistry in cell signaling and disease, Proteomics
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Keith B. Hengen, Ph.D.
- We take a "big data" approach to understanding the self-organization of neurons and networks in behaving animals.
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Andreas Herrlich, M.D., Ph.D.
- We aim to identify cellular and molecular mechanisms in the novel and rapidly expanding field of interorgan crosstalk in health and disease.
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Erik D. Herzog, Ph.D.
- Molecular, cellular and circuit analysis of circadian rhythms in mammals
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Angela Hirbe, M.D., Ph.D.
- Utilization of genomic information from sarcomas to better understand the pathogenesis of these tumors and to identify biomarkers and therapeutic targets for these aggressive cancers.
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Didier Hodzic, Ph.D.
- Role of LINC complexes (Linkers of the Nucleoskeleton to the Cytoskeleton) in nucleokinesis and neuronal migration
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Alex Holehouse, Ph.D.
- Understand how function is encoded into disordered sequences using a combination of computational and experimental approaches
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David M. Holtzman, M.D.
- Cellular and Molecular studies of Alzheimer’s disease
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Michael J. Holtzman, M.D.
- Pathogenesis and new therapeutics for viral infection and post-viral disease
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Amjad Horani, M.D.
- Our lab studies airway and motile cilia biology and investigates the effects of mutations on cilia function
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Jianghui Hou, Ph.D.
- Cell-cell junctions that form epithelial barriers to ions and solutes critical for normal kidney functions
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Paul W. Hruz, Ph.D., M.D.
- Structural Biology and Regulation of Glucose Transport; Molecular Mechanisms Leading to Insulin Resistance
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James J. Hsieh, M.D., Ph.D.
- Integrate contemporary research tools to quickly improve human cancer care
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Hongzhen Hu, Ph.D.
- Neuroimmune mechanisms of sensory processing at barrier surfaces
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James E. Huettner, Ph.D.
- Glutamate receptors, synaptic transmission and stem cell differentiation
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Jing W. Hughes, M.D., Ph.D.
- Cilia functions in islet cell crosstalk, beta cells in diabetes, live-cell microscopy
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Scott J. Hultgren, Ph.D.
- Interdisciplinary approach combining genetics, genomics, biochemistry, structural biology, high-resolution imaging, animal models, clinical studies and combinatorial chemistry to determine key aspects of bacterial pathogenesis and apply our knowledge to development of new therapeutics.
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Shin-ichiro Imai, M.D., Ph.D.
- Understanding the molecular mechanism of aging and longevity in mammals
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Joseph Ippolito, M.D., Ph.D.
- Precision medicine through metabolism-based imaging and therapy: from laboratory to clinical translation
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Meredith E. Jackrel, Ph.D.
- Protein folding and misfolding, and the engineering and application of protein disaggregases to reverse misfolding
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James W. Janetka, Ph.D.
- The rational structure-based drug design and synthesis for cancer and infectious disease
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Silvia Jansen, Ph.D.
- we study the molecular mechanisms that regulate the architecture, dimensions and dynamics of actin filament networks, and tune them to support essential cellular functions including cell migration, intracellular trafficking and cytokinesis.
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Yoon A Kang, Ph.D.
- Decoding cell fate decision mechanisms to modulate lineage output for therapeutic purpose
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Celeste M. Karch, Ph.D.
- Understanding the molecular and cellular mechanisms underlying tauopathies
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David Kast, Ph.D.
- Understand fundamental cellular and molecular mechanisms that drive the biogenesis and dynamics of intracellular membrane compartments
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