​Molecular Cell Biology Faculty

   
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  • Yousef Abu-Amer, PhD - Investigating molecular mechanisms underlying inflammation-induced degenerative skeletal diseases including joint degeneration, inflammatory arthritis and osteolysis
  • Nada A. Abumrad, PhD - Fatty acids regulate energy balance and tissue renewal. Dysfunction of this regulation causes disease
  • Gustav Akk, PhD - Function and modulation of transmitter-gated ion channels
  • Ream Al-Hasani, PhD - Understanding the endogenous opioid systems to defeat addiction, ameliorate affective disorders, and relieve chronic pain.
  • Ghazaleh Ashrafi, PhD - Uncovering novel regulators of glycolytic and mitochondrial metabolism at the synapse and their role in the pathology of Alzheimer’s disease
  • Monika Bambouskova, PhD - Immunometabolism - metabolic regulation of immune cell activation
  • Thomas J. Baranski, MD, PhD - Signal transduction by G proteins and pathogenesis of diabetes
  • David L. Bark, PhD - Applying biomechanics and mechanobiology (the interaction and response of cells and tissue to mechanical forces) to diagnose, study, and treat various forms of cardiovascular disease.
  • Steven Bassnett, PhD - Ocular cell biology
  • Luis F.Z. Batista, PhD - Understanding the role of DNA damage and RNA degradation during tissue homeostasis, regeneration, aging, and cancer
  • Jeffrey J. Bednarski II, MD, PhD - Understanding the signals that direct early B cell development
  • Carmen Bergom, MD, PhD - Identification of new targets to improve tumor radiation effectiveness and to protect normal tissues such as the heart from radiation injury
  • Carlos Bernal-Mizrachi, MD - Novel mechanisms of cardiovascular disease in human and mouse models with insulin resistance and type 2 DM
  • Matthew R. Bersi, PhD - Our research is focused on soft tissue biomechanics and mechanobiology
  • Kendall J. Blumer, PhD - Tumor cell biology, signal transduction, and drug development
  • Irving Boime, PhD - Placental and pituitary hormone genes
  • Ron Bose, MD, PhD - Genomics and Cell Signaling in Breast Cancer
  • Jonathan R. Brestoff, MD, PhD, MPH - Understanding how immune cells and metabolic organs interact to maintain normal metabolism and to support adaptation to physiologic challenges
  • Paul C. Bridgman, PhD - Cell biology of developing nerve and muscle cells
  • Steven Brody, MD - Molecular and genetic mechanisms of airway epithelial cell differentiation and ciliogenesis
  • Peter M.J. Burgers, PhD - Molecular Biology of DNA replication and damage response in yeast and human
  • Valeria Cavalli, PhD - Cellular, Molecular and Epigenetic control of axon regeneration
  • Grant Challen, PhD - Understanding the genetic and epigenetic mechanisms that regulate normal and leukemic stem cells
  • Tao Che, PhD - Characterizing and dissecting the molecular mechanisms of opioid receptor signaling
  • Hong Chen, PhD - Combines biology, engineering, and medicine to develop ultrasound techniques for noninvasive, targeted, and personalized brain cancer treatment
  • Yao Chen, PhD - Understanding the function of neuromodulators and sleep through the spatiotemporal dynamics of molecular signals
  • Ying Maggie Chen, MD, PhD - Understanding the molecular mechanisms of primary nephrotic syndrome (NS)
  • Wayland W. L. Cheng, MD, PhD - I am interested in the structure and function of neuronal ligand-gated ion channels, and the mechanism of channel modulation by endogenous lipids or exogenous drugs such as general anesthetics.
  • Jaehyung (Gus) Cho, PhD - Understanding the mechanism mediating intravascular cell-cell interactions and vascular occlusion under thromboinflammatory conditions, including thrombosis, ischemia/reperfusion injury, and sickle cell disease
  • Jaebok Choi, PhD - Understanding T cells and immunoregulatory networks in GvHD and GvL for the treatment of hematopoietic malignancies.
  • Kyunghee Choi, PhD - Angioimmune interface in development, tissue regeneration, and cancer
  • Matt Christopher, MD, PhD - Improve outcomes for patients with acute myeloid leukemia (AML) and other hematopoietic malignancies utilizing genomic and molecular biology techniques
  • Roberto Civitelli, MD - Connexins, cadherins in bone cell interactions with cancer and energy metabolism
  • Regina Clemens, MD, PhD - The mechanisms regulating calcium-dependent neutrophil activation
  • Clair Crewe, PhD - Understanding extracellular vesicle (EV)-mediated signaling during homeostatic and pathologic metabolic regulation
  • Erika C. Crouch, PhD, MD - Structure and function of surfactant protein D (SP-D)
  • Nicholas O. Davidson, MD - Mammalian gene expression: Regulation through mRNA editing and RNA stabilization
  • Gus Davis, MD, PhD - Understanding the molecular and cellular mechanisms of protein aggregation and neurodegeneration in Parkinson disease and dementia with Lewy bodies
  • Brian J. DeBosch, MD, PhD - To elucidate gut and hepatic determinants of metabolic disease, including diabetes mellitus, metabolic syndrome and their complications
  • David G. DeNardo, PhD - Molecular Mechanisms of Immune Regulation of Tumor Progression.
  • Carl DeSelm, MD, PhD - Dr. DeSelm clinically focuses on treating lymphoma, and is actively developing novel CAR T cell approaches to treating solid tumors, including lymphoma, pancreatic cancer and glioblastoma.
  • Jorge Di Paola, MD - The genetics of bleeding and thrombotic disorders and mechanisms of platelet activation
  • Mary C. Dinauer, MD, PhD - Role of leukocyte NADPH oxidase in innate immunity, inflammation, and autoimmunity
  • Siyuan Ding, PhD - Understanding how rotavirus (RV), an important enteric viral pathogen, interacts with the host innate immune system in the small intestine
  • Abhinav Diwan, MD, FACC, FAHA - Transcriptional regulation of lysosome machinery under stress
  • Ram Dixit, PhD - Molecular mechanisms of cytoskeleton organization and function
  • Sergej Djuranovic, PhD - Molecular mechanisms of translational control
  • Tamara L. Doering, MD, PhD - Biology and pathogenesis of the pathogenic fungus Cryptococcus neoformans
  • Gerald W. Dorn, II, MD - Cellular, Molecular, And Genetic Studies Of Cardiac Hypertrophy And Heart Failure
  • Susan K. Dutcher, PhD
  • Gabor Egervari, PhD - We aim to understand how metabolism influences epigenetics, gene expression and behavior, particularly in the context of substance use disorders and neurodegeneration
  • Elliot L. Elson, PhD - Mechanical properties of reconstituted tissues; fluctuation spectroscopy of protein interactions
  • Sarah England, PhD - Molecular mechanisms underlying uterine function during pregnancy
  • Roberta Faccio, PhD - interactions between bone and immune cells in inflammation and cancer
  • Thomas A. Ferguson, PhD - We are examining the role of the autophagy pathway in the function of the retina and its role in diseases of the eye
  • Francesca Ferraro, MD, PhD - We use both mouse models and patient samples of acute myloid leukemia to understand leukemogenesis and to identify novel therapeutic targets.
  • Brian N. Finck, PhD - Identify novel target pathways for therapeutic treatment of obesity-related diseases including diabetes, cardiovascular disease, and fatty liver disease
  • Antonina Frolova, MD, PhD - Improve obstetric outcomes for women and their neonates by understanding and targeting mechanisms of dysfunctional uterine contractility
  • Harrison W. Gabel, PhD - Exploration of functions for neuron-specific regulators of gene expression, leveraging genes and mechanisms implicated in human neurologic disease to point us toward critical pathways in the brain.
  • Gilbert Gallardo, PhD - Understand the molecular mechanisms that regulate reactive astrocytes and their neurotoxicity in neurodegenerative diseases, including Alzheimer’s disease, by utilizing a combination of biochemistry, molecular biology, cellular models of inflammation and mouse models of neurodegenerative diseases.
  • Robert W. Gereau, PhD - Cellular and molecular mechanisms of chronic pain, preclinical and translational research
  • Leslie Gewin, MD - Mechanisms of chronic kidney disease progression, treatment options to halt kidney disease progression
  • Daniel E. Goldberg, MD, PhD - Biochemistry of malaria
  • Dennis Goldfarb, PhD - Computational mass spectrometry and proteomics
  • Matthew L. Goodwin, MD, PhD - Metabolism of cancer, targeting tumor metabolism by blocking metabolic pathways
  • Jeffrey I. Gordon, MD - Role of the human gut microbiome in health and disease, notably childhood undernutrition and obesity
  • Gregory A. Grant, PhD - Relationship of structure to function in allosteric control mechanisms
  • Abby M. Green, MD - The etiology of mutagenesis and genome instability in pediatric cancers
  • Michael J. Greenberg, PhD - The Greenberg lab seeks to understand the molecular and cellular biophysics of heart disease, with the goal of engineering disease models and precision therapeutics
  • Eric Greer, PhD - Deciphering the molecular mechanisms of epigenetics and how when this goes awry diseases arise
  • Obi L. Griffith, PhD - Development of personalized medicine strategies for cancer using genomic technologies
  • Richard W. Gross, MD, PhD - The molecular mechanisms through which biologic membranes participate in cellular activation processes
  • Farshid Guilak, PhD - Application of stem cells and mechanobiology in the onset, progression, and treatment of osteoarthritis and other joint diseases.
  • Carmen Halabi, MD, PhD - Understanding how the extracellular matrix (ECM) contributes to normal arterial development and how its disruptionleads to abnormal vascular development and disease
  • Dennis E. Hallahan, MD - The mechanisms of cell death in normal tissues during cancer therapy
  • Jeffrey Haspel, MD, PhD - Understand the impact of time as a biological variable in the development of critical illness such as sepsis, respiratory failure and chronic inflammatory lung disease
  • Elizabeth S. Haswell, PhD - Mechanobiology with a focus on mechanosensitive ion channels
  • Jason M. Held, PhD - Redox biochemistry in cell signaling and disease, Proteomics
  • Keith B. Hengen, PhD - We take a "big data" approach to understanding the self-organization of neurons and networks in behaving animals.
  • Andreas Herrlich, MD, PhD - We aim to identify cellular and molecular mechanisms in the novel and rapidly expanding field of interorgan crosstalk in health and disease.
  • Erik D. Herzog, PhD - Molecular, cellular and circuit analysis of circadian rhythms in mammals
  • Angela Hirbe, MD, PhD - Utilization of genomic information from sarcomas to better understand the pathogenesis of these tumors and to identify biomarkers and therapeutic targets for these aggressive cancers.
  • Didier Hodzic, PhD - Role of LINC complexes (Linkers of the Nucleoskeleton to the Cytoskeleton) in nucleokinesis and neuronal migration
  • Alex Holehouse, PhD - Understand how function is encoded into disordered sequences using a combination of computational and experimental approaches
  • David M. Holtzman, MD - Cellular and Molecular studies of Alzheimer’s disease
  • Michael J. Holtzman, MD - Pathogenesis and new therapeutics for viral infection and post-viral disease
  • Amjad Horani, MD - Our lab studies airway and motile cilia biology and investigates the effects of mutations on cilia function
  • Jianghui Hou, PhD - Cell-cell junctions that form epithelial barriers to ions and solutes critical for normal kidney functions
  • Paul W. Hruz, PhD, MD - Structural Biology and Regulation of Glucose Transport; Molecular Mechanisms Leading to Insulin Resistance
  • James J. Hsieh, MD, PhD - Integrate contemporary research tools to quickly improve human cancer care
  • Hongzhen Hu, PhD - Neuroimmune mechanisms of sensory processing at barrier surfaces
  • James E. Huettner, PhD - Glutamate receptors, synaptic transmission and stem cell differentiation
  • Jing W. Hughes, MD, PhD - Cilia functions in islet cell crosstalk, beta cells in diabetes, live-cell microscopy
  • Scott J. Hultgren, PhD - Interdisciplinary approach combining genetics, genomics, biochemistry, structural biology, high-resolution imaging, animal models, clinical studies and combinatorial chemistry to determine key aspects of bacterial pathogenesis and apply our knowledge to development of new therapeutics.
  • Shin-ichiro Imai, MD, PhD - Understanding the molecular mechanism of aging and longevity in mammals
  • Joseph Ippolito, MD, PhD - Precision medicine through metabolism-based imaging and therapy: from laboratory to clinical translation
  • Meredith E. Jackrel, PhD - Protein folding and misfolding, and the engineering and application of protein disaggregases to reverse misfolding
  • James W. Janetka, PhD - The rational structure-based drug design and synthesis for cancer and infectious disease
  • Silvia Jansen, PhD - we study the molecular mechanisms that regulate the architecture, dimensions and dynamics of actin filament networks, and tune them to support essential cellular functions including cell migration, intracellular trafficking and cytokinesis.
  • Yoon A Kang, PhD - Decoding cell fate decision mechanisms to modulate lineage output for therapeutic purpose
   
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