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Yousef Abu-Amer, PhD
- Investigating molecular mechanisms underlying inflammation-induced degenerative skeletal diseases including joint degeneration, inflammatory arthritis and osteolysis
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Nada A. Abumrad, PhD
- Fatty acids regulate energy balance and tissue renewal. Dysfunction of this regulation causes disease
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Gustav Akk, PhD
- Function and modulation of transmitter-gated ion channels
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Ream Al-Hasani, PhD
- Understanding the endogenous opioid systems to defeat addiction, ameliorate affective disorders, and relieve chronic pain.
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Ghazaleh Ashrafi, PhD
- Uncovering novel regulators of glycolytic and mitochondrial metabolism at the synapse and their role in the pathology of Alzheimer’s disease
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Monika Bambouskova, PhD
- Immunometabolism - metabolic regulation of immune cell activation
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Thomas J. Baranski, MD, PhD
- Signal transduction by G proteins and pathogenesis of diabetes
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David L. Bark, PhD
- Applying biomechanics and mechanobiology (the interaction and response of cells and tissue to mechanical forces) to diagnose, study, and treat various forms of cardiovascular disease.
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Steven Bassnett, PhD
- Ocular cell biology
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Luis F.Z. Batista, PhD
- Understanding the role of DNA damage and RNA degradation during tissue homeostasis, regeneration, aging, and cancer
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Jeffrey J. Bednarski II, MD, PhD
- Understanding the signals that direct early B cell development
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Carmen Bergom, MD, PhD
- Identification of new targets to improve tumor radiation effectiveness and to protect normal tissues such as the heart from radiation injury
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Carlos Bernal-Mizrachi, MD
- Novel mechanisms of cardiovascular disease in human and mouse models with insulin resistance and type 2 DM
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Matthew R. Bersi, PhD
- Our research is focused on soft tissue biomechanics and mechanobiology
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Kendall J. Blumer, PhD
- Tumor cell biology, signal transduction, and drug development
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Irving Boime, PhD
- Placental and pituitary hormone genes
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Ron Bose, MD, PhD
- Genomics and Cell Signaling in Breast Cancer
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Jonathan R. Brestoff, MD, PhD, MPH
- Understanding how immune cells and metabolic organs interact to maintain normal metabolism and to support adaptation to physiologic challenges
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Paul C. Bridgman, PhD
- Cell biology of developing nerve and muscle cells
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Steven Brody, MD
- Molecular and genetic mechanisms of airway epithelial cell differentiation and ciliogenesis
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Peter M.J. Burgers, PhD
- Molecular Biology of DNA replication and damage response in yeast and human
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Valeria Cavalli, PhD
- Cellular, Molecular and Epigenetic control of axon regeneration
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Grant Challen, PhD
- Understanding the genetic and epigenetic mechanisms that regulate normal and leukemic stem cells
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Tao Che, PhD
- Characterizing and dissecting the molecular mechanisms of opioid receptor signaling
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Hong Chen, PhD
- Combines biology, engineering, and medicine to develop ultrasound techniques for noninvasive, targeted, and personalized brain cancer treatment
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Yao Chen, PhD
- Understanding the function of neuromodulators and sleep through the spatiotemporal dynamics of molecular signals
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Ying Maggie Chen, MD, PhD
- Understanding the molecular mechanisms of primary nephrotic syndrome (NS)
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Wayland W. L. Cheng, MD, PhD
- I am interested in the structure and function of neuronal ligand-gated ion channels, and the mechanism of channel modulation by endogenous lipids or exogenous drugs such as general anesthetics.
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Jaehyung (Gus) Cho, PhD
- Understanding the mechanism mediating intravascular cell-cell interactions and vascular occlusion under thromboinflammatory conditions, including thrombosis, ischemia/reperfusion injury, and sickle cell disease
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Jaebok Choi, PhD
- Understanding T cells and immunoregulatory networks in GvHD and GvL for the treatment of hematopoietic malignancies.
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Kyunghee Choi, PhD
- Angioimmune interface in development, tissue regeneration, and cancer
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Matt Christopher, MD, PhD
- Improve outcomes for patients with acute myeloid leukemia (AML) and other hematopoietic malignancies utilizing genomic and molecular biology techniques
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Roberto Civitelli, MD
- Connexins, cadherins in bone cell interactions with cancer and energy metabolism
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Regina Clemens, MD, PhD
- The mechanisms regulating calcium-dependent neutrophil activation
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Clair Crewe, PhD
- Understanding extracellular vesicle (EV)-mediated signaling during homeostatic and pathologic metabolic regulation
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Erika C. Crouch, PhD, MD
- Structure and function of surfactant protein D (SP-D)
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Nicholas O. Davidson, MD
- Mammalian gene expression: Regulation through mRNA editing and RNA stabilization
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Gus Davis, MD, PhD
- Understanding the molecular and cellular mechanisms of protein aggregation and neurodegeneration in Parkinson disease and dementia with Lewy bodies
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Brian J. DeBosch, MD, PhD
- To elucidate gut and hepatic determinants of metabolic disease, including diabetes mellitus, metabolic syndrome and their complications
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David G. DeNardo, PhD
- Molecular Mechanisms of Immune Regulation of Tumor Progression.
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Carl DeSelm, MD, PhD
- Dr. DeSelm clinically focuses on treating lymphoma, and is actively developing novel CAR T cell approaches to treating solid tumors, including lymphoma, pancreatic cancer and glioblastoma.
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Jorge Di Paola, MD
- The genetics of bleeding and thrombotic disorders and mechanisms of platelet activation
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Mary C. Dinauer, MD, PhD
- Role of leukocyte NADPH oxidase in innate immunity, inflammation, and autoimmunity
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Siyuan Ding, PhD
- Understanding how rotavirus (RV), an important enteric viral pathogen, interacts with the host innate immune system in the small intestine
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Abhinav Diwan, MD, FACC, FAHA
- Transcriptional regulation of lysosome machinery under stress
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Ram Dixit, PhD
- Molecular mechanisms of cytoskeleton organization and function
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Sergej Djuranovic, PhD
- Molecular mechanisms of translational control
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Tamara L. Doering, MD, PhD
- Biology and pathogenesis of the pathogenic fungus Cryptococcus neoformans
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Gerald W. Dorn, II, MD
- Cellular, Molecular, And Genetic Studies Of Cardiac Hypertrophy And Heart Failure
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Susan K. Dutcher, PhD
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Gabor Egervari, PhD
- We aim to understand how metabolism influences epigenetics, gene expression and behavior, particularly in the context of substance use disorders and neurodegeneration
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Elliot L. Elson, PhD
- Mechanical properties of reconstituted tissues; fluctuation spectroscopy of protein interactions
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Sarah England, PhD
- Molecular mechanisms underlying uterine function during pregnancy
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Roberta Faccio, PhD
- interactions between bone and immune cells in inflammation and cancer
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Thomas A. Ferguson, PhD
- We are examining the role of the autophagy pathway in the function of the retina and its role in diseases of the eye
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Francesca Ferraro, MD, PhD
- We use both mouse models and patient samples of acute myloid leukemia to understand leukemogenesis and to identify novel therapeutic targets.
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Brian N. Finck, PhD
- Identify novel target pathways for therapeutic treatment of obesity-related diseases including diabetes, cardiovascular disease, and fatty liver disease
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Antonina Frolova, MD, PhD
- Improve obstetric outcomes for women and their neonates by understanding and targeting mechanisms of dysfunctional uterine contractility
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Harrison W. Gabel, PhD
- Exploration of functions for neuron-specific regulators of gene expression, leveraging genes and mechanisms implicated in human neurologic disease to point us toward critical pathways in the brain.
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Gilbert Gallardo, PhD
- Understand the molecular mechanisms that regulate reactive astrocytes and their neurotoxicity in
neurodegenerative diseases, including Alzheimer’s disease, by utilizing a combination of biochemistry, molecular biology, cellular models of inflammation and mouse models of neurodegenerative diseases.
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Robert W. Gereau, PhD
- Cellular and molecular mechanisms of chronic pain, preclinical and translational research
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Leslie Gewin, MD
- Mechanisms of chronic kidney disease progression, treatment options to halt kidney disease progression
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Daniel E. Goldberg, MD, PhD
- Biochemistry of malaria
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Dennis Goldfarb, PhD
- Computational mass spectrometry and proteomics
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Matthew L. Goodwin, MD, PhD
- Metabolism of cancer, targeting tumor metabolism by blocking metabolic pathways
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Jeffrey I. Gordon, MD
- Role of the human gut microbiome in health and disease, notably childhood undernutrition and obesity
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Gregory A. Grant, PhD
- Relationship of structure to function in allosteric control mechanisms
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Abby M. Green, MD
- The etiology of mutagenesis and genome instability in pediatric cancers
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Michael J. Greenberg, PhD
- The Greenberg lab seeks to understand the molecular and cellular biophysics of heart disease, with the goal of engineering disease models and precision therapeutics
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Eric Greer, PhD
- Deciphering the molecular mechanisms of epigenetics and how when this goes awry diseases arise
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Obi L. Griffith, PhD
- Development of personalized medicine strategies for cancer using genomic technologies
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Richard W. Gross, MD, PhD
- The molecular mechanisms through which biologic membranes participate in cellular activation processes
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Farshid Guilak, PhD
- Application of stem cells and mechanobiology in the onset, progression, and treatment of osteoarthritis and other joint diseases.
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Carmen Halabi, MD, PhD
- Understanding how the extracellular matrix (ECM) contributes to normal arterial development and how its disruptionleads to abnormal vascular development and disease
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Dennis E. Hallahan, MD
- The mechanisms of cell death in normal tissues during cancer therapy
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Jeffrey Haspel, MD, PhD
- Understand the impact of time as a biological variable in the development of critical illness such as sepsis, respiratory failure and chronic inflammatory lung disease
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Elizabeth S. Haswell, PhD
- Mechanobiology with a focus on mechanosensitive ion channels
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Jason M. Held, PhD
- Redox biochemistry in cell signaling and disease, Proteomics
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Keith B. Hengen, PhD
- We take a "big data" approach to understanding the self-organization of neurons and networks in behaving animals.
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Andreas Herrlich, MD, PhD
- We aim to identify cellular and molecular mechanisms in the novel and rapidly expanding field of interorgan crosstalk in health and disease.
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Erik D. Herzog, PhD
- Molecular, cellular and circuit analysis of circadian rhythms in mammals
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Angela Hirbe, MD, PhD
- Utilization of genomic information from sarcomas to better understand the pathogenesis of these tumors and to identify biomarkers and therapeutic targets for these aggressive cancers.
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Didier Hodzic, PhD
- Role of LINC complexes (Linkers of the Nucleoskeleton to the Cytoskeleton) in nucleokinesis and neuronal migration
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Alex Holehouse, PhD
- Understand how function is encoded into disordered sequences using a combination of computational and experimental approaches
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David M. Holtzman, MD
- Cellular and Molecular studies of Alzheimer’s disease
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Michael J. Holtzman, MD
- Pathogenesis and new therapeutics for viral infection and post-viral disease
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Amjad Horani, MD
- Our lab studies airway and motile cilia biology and investigates the effects of mutations on cilia function
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Jianghui Hou, PhD
- Cell-cell junctions that form epithelial barriers to ions and solutes critical for normal kidney functions
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Paul W. Hruz, PhD, MD
- Structural Biology and Regulation of Glucose Transport; Molecular Mechanisms Leading to Insulin Resistance
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James J. Hsieh, MD, PhD
- Integrate contemporary research tools to quickly improve human cancer care
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Hongzhen Hu, PhD
- Neuroimmune mechanisms of sensory processing at barrier surfaces
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James E. Huettner, PhD
- Glutamate receptors, synaptic transmission and stem cell differentiation
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Jing W. Hughes, MD, PhD
- Cilia functions in islet cell crosstalk, beta cells in diabetes, live-cell microscopy
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Scott J. Hultgren, PhD
- Interdisciplinary approach combining genetics, genomics, biochemistry, structural biology, high-resolution imaging, animal models, clinical studies and combinatorial chemistry to determine key aspects of bacterial pathogenesis and apply our knowledge to development of new therapeutics.
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Shin-ichiro Imai, MD, PhD
- Understanding the molecular mechanism of aging and longevity in mammals
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Joseph Ippolito, MD, PhD
- Precision medicine through metabolism-based imaging and therapy: from laboratory to clinical translation
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Meredith E. Jackrel, PhD
- Protein folding and misfolding, and the engineering and application of protein disaggregases to reverse misfolding
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James W. Janetka, PhD
- The rational structure-based drug design and synthesis for cancer and infectious disease
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Silvia Jansen, PhD
- we study the molecular mechanisms that regulate the architecture, dimensions and dynamics of actin filament networks, and tune them to support essential cellular functions including cell migration, intracellular trafficking and cytokinesis.
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Yoon A Kang, PhD
- Decoding cell fate decision mechanisms to modulate lineage output for therapeutic purpose
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