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Jennifer Alexander-Brett, M.D., Ph.D.
- Respiratory immunobiology, with particular interest in cytokine pathways associated with lung epithelial progenitors
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Paul M. Allen, Ph.D.
- Recognition of antigen by T cells
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Gaya K. Amarasinghe, Ph.D.
- Signaling through interferons: Mechanisms and implications for viral pathogenesis and cancer biology
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Maxim Artyomov, Ph.D.
- Systems immunology using high-throughput next-generation sequencing in conjunction with mathematical and statistical modeling approaches rooted in statistical physics
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John P. Atkinson, M.D.
- Complement activation and regulation in innate and adaptive immunity
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Kareem Azab, Ph.D.
- We investigate the mechanisms of neoplasia and metastasis, and develop targeted drug-delivery-systems for cancer treatment.
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Megan T. Baldridge, M.D., Ph.D.
- Defining the mechanisms behind and effects of the interactions between commensal bacteria, pathogens and innate immunity
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Jeffrey J. Bednarski II, M.D., Ph.D.
- Understanding the signals that direct early B cell development
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Matthew R. Bersi, Ph.D.
- Our research is focused on soft tissue biomechanics and mechanobiology
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Stephen M. Beverley, Ph.D.
- Molecular genetics of protozoan parasites - virulence and their viruses
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Jacco Boon, Ph.D.
- Pathogenesis of Influenza A viruses
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Jonathan R. Brestoff, M.D., Ph.D., MPH.
- Understanding how immune cells and metabolic organs interact to maintain normal metabolism and to support adaptation to physiologic challenges
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Thomas J. Brett, Ph.D.
- The molecular basis of lung diseases and drug development using structural biology tools
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Juliane Bubeck Wardenburg, M.D., Ph.D.
- The research in my laboratory is aimed at understanding fundamental principles of the interaction between bacterial pathogens and the human host.
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Thomas P. Burris, Ph.D.
- Pharmacology and chemical biology of nuclear receptors.
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Milan G. Chheda, M.D.
- Cancer stem cells, oncolytic viruses, and functional genomics of brain tumors
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Jaehyung (Gus) Cho, Ph.D.
- Understanding the mechanism mediating intravascular cell-cell interactions and vascular occlusion under thromboinflammatory conditions, including thrombosis, ischemia/reperfusion injury, and sickle cell disease
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Jaebok Choi, Ph.D.
- Understanding T cells and immunoregulatory networks in GvHD and GvL for the treatment of hematopoietic malignancies.
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Kyunghee Choi, Ph.D.
- Hematopoietic and endothelial development and the interplay between angiogenesis and immunity in cancer
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Matthew A. Ciorba, M.D.
- Tryptophan metabolism and probiotic bacteria as modifiers of intestinal cancer and inflammation
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Regina Clemens, M.D., Ph.D.
- The mechanisms regulating calcium-dependent neutrophil activation
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Marco Colonna, M.D.
- Innate immune responses in infections, autoimmunity and tumors
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Megan A. Cooper, M.D., Ph.D.
- The biology of natural killer (NK) cells and genetic investigation of primary immune dysregulation syndromes
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David T. Curiel, M.D., Ph.D.
- To address the central mandate of gene therapy we engineer adenovirus tropism to allow the achievement of effective gene delivery
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Gus Davis, M.D., Ph.D.
- Understanding the molecular and cellular mechanisms of protein aggregation and neurodegeneration in Parkinson disease and dementia with Lewy bodies
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David G. DeNardo, Ph.D.
- Molecular Mechanisms of Immune Regulation of Tumor Progression.
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Carl DeSelm, M.D., Ph.D.
- Dr. DeSelm clinically focuses on treating lymphoma, and is actively developing novel CAR T cell approaches to treating solid tumors, including lymphoma, pancreatic cancer and glioblastoma.
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Michael S. Diamond, M.D., Ph.D.
- Innate and Adaptive Host Immunity to Viral Infections
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Mary C. Dinauer, M.D., Ph.D.
- Role of leukocyte NADPH oxidase in innate immunity, inflammation, and autoimmunity
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Siyuan Ding, Ph.D.
- Understanding how rotavirus (RV), an important enteric viral pathogen, interacts with the host innate immune system in the small intestine
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Gavin P. Dunn, M.D., Ph.D.
- The immunobiology of malignant glioma with the goal of translational and clinical trial efforts in the treatment of this disease
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Brian T. Edelson, M.D., Ph.D.
- Immune cell development and function
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Takeshi Egawa, M.D., Ph.D.
- Gene regulation for lymphocyte development and adaptive immune responses
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Ali H. Ellebedy, Ph.D.
- Defining the cellular and molecular mechanisms that regulate memory B cell heterogeneity and fate.
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Roberta Faccio, Ph.D.
- interactions between bone and immune cells in inflammation and cancer
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Todd A. Fehniger, M.D., Ph.D.
- My laboratory is focused on the molecular mechanisms regulating natural killer cell activation, novel methods to use NK cells as immunotherapy for cancer, and lymphoma genomics.
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Thomas A. Ferguson, Ph.D.
- We are examining the role of the autophagy pathway in the function of the retina and its role in diseases of the eye
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Daved H. Fremont, Ph.D.
- Mechanisms of host immunity and viral evasion
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Anthony R. French, Ph.D., M.D.
- In vivo NK cell responses during viral infections
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William E. Gillanders, M.D.
- Development of a breast cancer vaccine
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Misty L. Good, M.D., M.S.
- Focus on the cellular and molecular mechanisms involved in the development of necrotizing enterocolitis (NEC), a disease affecting the intestine of premature babies
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Farshid Guilak, Ph.D.
- Focuses on the role of biomechanical factors in the onset, progression, and treatment of osteoarthritis and other joint diseases.
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Daniel F. Hanson, Ph.D.
- Fever as an evolutionarily adaptive regulator of immune host defense
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Michael J. Holtzman, M.D.
- Pathogenesis and new therapeutics for viral infection and post-viral disease
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Chyi-Song Hsieh, M.D., Ph.D.
- Understanding T cell tolerance to self and non-self
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Hongzhen Hu, Ph.D.
- Neuroimmune mechanisms of sensory processing at barrier surfaces
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Andrew L. Kau, M.D., Ph.D.
- Understanding the immune-modifying capacity of gastrointestinal and airway microbes through the lens of allergy
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Peggy L. Kendall, MD
- The role of B lymphocytes in autoimmune disease
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Shabaana A. Khader, Ph.D.
- Understanding lung host immunity to intracellular pathogens
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Alfred H.J. Kim, M.D., Ph.D.
- Identifying the role of cytokines in glomerular injury
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Brian S. Kim, M.D.
- Understanding the intersection of immunity and sensory perception
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Jonathan Kipnis, Ph.D.
- We study complex interactions between the immune and nervous systems in health and disease
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Eynav Klechevsky, Ph.D.
- Human Dendritic Cell biology and Novel vaccines
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Robyn S. Klein, M.D., Ph.D.
- Cellular and molecular studies of viral and autoimmune encephalitides
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Hrishikesh S. Kulkarni, M.D., MSCI
- Modulating the complement system to mitigate pneumonia and acute lung injury
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Sebla B. Kutluay, Ph.D.
- Human immunodeficiency virus-host interactions
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Brian Laidlaw, Ph.D.
- Investigating the development of immunological memory in disease states
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Kory J. Lavine, M.D., Ph.D.
- Identify signaling pathways that mediate cardiac tissue repair/regeneration and heart failure pathogenesis.
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Deborah J. Lenschow, M.D., Ph.D.
- Antiviral mechanisms of type I interferons and the role of interferons and viruses in autoimmune diseases
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Timothy J. Ley, M.D.
- Study of normal versus leukemic blood cell development and immunology
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Kian Lim, M.D., Ph.D.
- Understanding the role of inflammation in gastrointestinal cancers
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Daniel C. Link, M.D.
- Regulation of normal and malignant hematopoiesis
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Ta-Chiang Liu, M.D., Ph.D.
- Understanding how host genetics and environmental factors interact to shape gut metabolism leading to inflammation
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Gregory D. Longmore, M.D.
- Cell Motility and Cancer Metastasis
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Carolina B. López, Ph.D.
- The Lopez Lab studies how viruses interact with the body and how defective viruses influence the development of diseases in humans
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William H. McCoy, M.D., Ph.D.
- We investigate how host-microbe interactions at epithelial barrier sites impact skin diseases
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Mark James Miller, Ph.D.
- Lymphoid tissue dynamics and antigen-presentation during infection, cancer and autoimmunity
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Jonathan Miner, M.D., Ph.D.
- Innate immunity and host-pathogen interactions in autoimmunity.
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S. Celeste Morley, M.D., Ph.D.
- Cell biology of the immune system -- understanding how cytoskeletal control of cell motility and adhesion impacts host immunity to infection
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Kenneth M. Murphy, M.D., Ph.D.
- Selecting the correct immune response to pathogens – development of dendritic cells and lymphocyte subsets
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Indira U. Mysorekar, Ph.D.
- Mechanisms of mucosal defenses in the urinary bladder and placenta
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Rodney Newberry, M.D.
- Mucosal Immunology
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Stephen Oh, M.D., Ph.D.
- Mechanisms of dysregulated signaling in blood cancers
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David H. Perlmutter, M.D.
- Pathobiology of liver disease from accumulation and proteotoxicity of misfolded proteins in α1-antitrypsin deficiency; role of autophagy in biology and treatment of disorders caused by misfolded proteins
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Christine T.N. Pham, M.D.
- Immunity and autoimmunity in inflammatory diseases; nanotherapy in the treatment of inflammatory diseases
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Jennifer A. Philips, M.D., Ph.D.
- Immune Evasion by Mycobacterium tuberculosis
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Gwendalyn J Randolph, Ph.D.
- The lymphatic vasculature as a regulator of inflammation and homeostasis
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Babak Razani, M.D., Ph.D.
- Defining the mechanisms of atherosclerosis, obesity, and diabetes with a focus on the roles of autophagy and lysosomes
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David Rosen, M.D., Ph.D.
- Pathogenesis and host response to Klebsiella pneumoniae infections
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Naresha Saligrama, PhD
- Adaptive immune responses in neuroinflammatory, neurodegenerative, and neuropsychiatric diseases
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Joel Schilling, M.D., Ph.D.
- My research is focused on defining the role(s) of Toll-like Receptor mediated inflammation in heart failure associated with diabetes and obesity
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Robert D. Schreiber, Ph.D.
- Cytokine receptor signaling and immunological protection against tumor development
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Laura G. Schuettpelz, M.D., Ph.D.
- Regulation of hematopoietic stem cells (HSCs) by inflammation
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Liang Shan, Ph.D.
- HIV infection and host immune response in humanized mouse models
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Haina Shin, Ph.D.
- Examining immune responses against viruses that establish persistent infections in their hosts
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Monica Shokeen, Ph.D.
- Development and evaluation of small- and macro-molecular agents for multi-modal molecular imaging of cancer and cardiovascular diseases
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David Sibley, Ph.D.
- Cellular and molecular basis of intracellular parasitism by protozoan parasites
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Nathan Singh, M.D., M.S.
- Understanding how synthetic antigen receptors direct T cell function and dysfunction in the treatment of blood cancers
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Christina L. Stallings, Ph.D.
- Molecular pathogenesis of Mycobacterium tuberculosis
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Ashley L. Steed, M.D., Ph.D.
- Investigate the genetic and environmental factors that underlie the mechanistic basis for the heterogeneity in outcomes in response to infection
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Thorold Theunissen, Ph.D.
- Exploring the molecular regulation and applications of pluripotent stem cells.
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Adetunji T. Toriola, M.D., Ph.D.
- Associations of metabolic imbalance, inflamation with cancer etiology and survival
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Sandeep K. Tripathy, M.D., Ph.D.
- Receptor-mediated modulation of NK cell responses in vivo
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Emil R. Unanue, M.D.
- We examine basic immunology of autoimmune diabetes focusing on T cell biology
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Steven J. Van Dyken, Ph.D.
- Cytokine-mediated tissue feedback loops that maintain homeostasis, and environmental factors that instigate inflammation and fibrosis.
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Deborah J. Veis (Novack), M.D., Ph.D.
- Role of NF-KB signalling in bone loss, during bone metastasis, arthritis, and osteoporosis
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David Wang, Ph.D.
- Discovery and Characterization of Novel Viruses
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Jeffrey P. Ward, M.D., Ph.D.
- Identification of tumor specific mutant antigens recognized by the immune system as foreign that serve as the target of a T-cell response against tumors
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Sean P. J. Whelan, Ph.D.
- The Whelan laboratory studies the biology of negative-strand (NS) RNA viruses, divided between two major areas of focus: viral gene expression and viral-host cell interactions.
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Brian W. Wong, Ph.D.
- The overarching goal of my research is to understand the role of cellular metabolic pathways in the context of epigenetic modifications in lymphatic endothelial cells
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