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Gaya K. Amarasinghe, Ph.D.
- Molecular mechanisms at the host-pathogen interface
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Beau Ances, M.D., Ph.D.
- Characterization of Dementia (HIV associated neurocognitive disorders (HAND) and Alzheimer`s Disease (AD) using functional magnetic resonance imaging
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John P. Atkinson, M.D.
- Complement activation and regulation in innate and adaptive immunity
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Megan T. Baldridge, M.D., Ph.D.
- Defining the mechanisms behind and effects of the interactions between commensal bacteria, pathogens and innate immunity
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Rebecca Bart, Ph.D.
- Combining genetics with molecular and computational biology to learn about the mechanisms used by hosts and pathogens to recognize and respond to one another and the environment
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Stephen M. Beverley, Ph.D.
- Molecular genetics of protozoan parasites - virulence and their viruses
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Jacco Boon, Ph.D.
- Pathogenesis of Influenza A viruses
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Arpita Bose, Ph.D.
- Microbial metabolisms and their influence on biogeochemical cycling
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Juliane Bubeck Wardenburg, M.D., Ph.D.
- The research in my laboratory is aimed at understanding fundamental principles of the interaction between bacterial pathogens and the human host.
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Yin Cao, Sc.D., MPH
- Novel lifestyle, microbial, and genetic risk factors for lung and gastrointestinal cancers leveraging large-scale clinical and population-based cohorts with deep genetic and phenotypic data
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Michael G. Caparon, Jr, Ph.D.
- Genetics and virulence of the pathogenetic streptococci
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Douglas L. Chalker, Ph.D.
- Genetic and epigenetic regulation of developmentally programmed DNA rearrangements of Tetrahymena
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Matthew A. Ciorba, M.D.
- Tryptophan metabolism and probiotic bacteria as modifiers of intestinal cancer and inflammation
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Marco Colonna, M.D.
- Innate immune responses in infections, autoimmunity and tumors
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David T. Curiel, M.D., Ph.D.
- To address the central mandate of gene therapy we engineer adenovirus tropism to allow the achievement of effective gene delivery
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Gautam Dantas, Ph.D.
- (1) Dynamics, ecology, and evolution of antibiotic resistance, (2) Engineering enhanced probiotics to treat GI disorders, (3) Engineering microbial biofuel catalysts
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Michael S. Diamond, M.D., Ph.D.
- Innate and Adaptive Host Immunity to Viral Infections
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Mary C. Dinauer, M.D., Ph.D.
- Role of leukocyte NADPH oxidase in innate immunity, inflammation, and autoimmunity
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Siyuan Ding, Ph.D.
- Understanding how rotavirus (RV), an important enteric viral pathogen, interacts with the host innate immune system in the small intestine
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Tamara L. Doering, M.D., Ph.D.
- Investigations of capsule synthesis and host interactions of the pathogenic fungus Cryptococcus neoformans
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Brian T. Edelson, M.D., Ph.D.
- Immune cell development and function
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Ali H. Ellebedy, Ph.D.
- Defining the cellular and molecular mechanisms that regulate memory B cell heterogeneity and fate.
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Mario F. Feldman, Ph.D.
- Pathogenesis of multidrug resistant bacteria and biogenesis of bacterial vesicles in the human gut
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Thomas A. Ferguson, Ph.D.
- We are examining the role of the autophagy pathway in the function of the retina and its role in diseases of the eye
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James Fleckenstein, M.D.
- Molecular investigation of enterotoxigenic Escherichia coli (ETEC)
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Daved H. Fremont, Ph.D.
- Mechanisms of host immunity and viral evasion
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Anthony R. French, Ph.D., M.D.
- In vivo NK cell responses during viral infections
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Stephanie A. Fritz, M.D., MSCI
- Asking and answering critical questions to guide clinical practice and ameliorate childhood suffering due to staphylococcal disease
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Eric A. Galburt, Ph.D.
- Biophysical studies of transcription initiation in Eukaryotes and Mycobacterial tuberculosis
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Daniel E. Goldberg, M.D., Ph.D.
- Biochemistry of malaria
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Jeffrey I. Gordon, M.D.
- Role of the human gut microbiome in health and disease, notably childhood undernutrition and obesity
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Jeffrey Haspel, M.D., Ph.D.
- Understand the impact of time as a biological variable in the development of critical illness such as sepsis, respiratory failure and chronic inflammatory lung disease
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Elizabeth S. Haswell, Ph.D.
- Mechanobiology with a focus on mechanosensitive ion channels
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Jeffrey P. Henderson, M.D., Ph.D.
- Biochemical interactions between humans and bacteria in health and disease
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Michael J. Holtzman, M.D.
- Pathogenesis and new therapeutics for viral infection and post-viral disease
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Henry V. Huang, Ph.D.
- Molecular biology of Sindbis virus; antiviral drug design; monocyte differentiation
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Scott J. Hultgren, Ph.D.
- Interdisciplinary approach combining genetics, genomics, biochemistry, structural biology, high-resolution imaging, animal models, clinical studies and combinatorial chemistry to determine key aspects of bacterial pathogenesis and apply our knowledge to development of new therapeutics.
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David A. Hunstad, M.D.
- Sex differences, virulence mechanisms, and novel therapeutics in E. coli urinary tract infection
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James W. Janetka, Ph.D.
- The rational structure-based drug design and synthesis for cancer and infectious disease
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Andrew B. Janowski, M.D.
- Characterization of human diseases associated with novel viral infections
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Andrew L. Kau, M.D., Ph.D.
- Understanding the immune-modifying capacity of gastrointestinal and airway microbes through the lens of allergy
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Shabaana A. Khader, Ph.D.
- Understanding lung host immunity to intracellular pathogens
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Eynav Klechevsky, Ph.D.
- Human Dendritic Cell biology and Novel vaccines
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Robert G. Kranz, Ph.D.
- Gene regulation and biogenesis of extracellular components in bacteria
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F. Matthew Kuhlmann, M.D.
- The pre-clinical development of rationally designed Enterotoxigenic E. coli (ETEC) vaccines
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Hrishikesh S. Kulkarni, M.D., MSCI
- Modulating the complement system to mitigate pneumonia and acute lung injury
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Barbara N. Kunkel, Ph.D.
- Molecular genetic analysis of disease development in Pseudomonas syringae-Arabidopsis interactions
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Sebla B. Kutluay, Ph.D.
- Human immunodeficiency virus-host interactions
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Jennie Kwon, D.O., MSCI
- Dr. Kwon performs clinical and translational research focused on the microbial ecology of multidrug-resistant organisms (MDRO), and their relationship to the fecal microbiome and the microbiome of the built environment.
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George B. Kyei, M.B., Ch.B., Ph.D.
- HIV latency and reservoir maintenance
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Brian Laidlaw, Ph.D.
- Investigating the development of immunological memory in disease states
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Deborah J. Lenschow, M.D., Ph.D.
- Antiviral mechanisms of type I interferons and the role of interferons and viruses in autoimmune diseases
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Daisy W. Leung, Ph.D.
- Defining molecular mechanisms at the host-pathogen interface
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Petra Anne Levin, Ph.D.
- Bacterial growth and antibiotic susceptibility
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Fangqiong Ling, Ph.D.
- A computational and experimental lab studying bacterial colonization and transmission at the boundary of built and natural environments and exploring microbiomes as environmental sensors and public health sentinels
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Ta-Chiang Liu, M.D., Ph.D.
- Understanding how host genetics and environmental factors interact to shape gut metabolism leading to inflammation
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Carolina B. López, Ph.D.
- The Lopez Lab studies how viruses interact with the body and how defective viruses influence the development of diseases in humans
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Todd P. Margolis, M.D., Ph.D.
- The cellular and molecular mechanisms that regulate the establishment and maintenance of latent neuronal infection with herpes simplex virus (HSV).
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William H. McCoy, M.D., Ph.D.
- We investigate how host-microbe interactions at epithelial barrier sites impact skin diseases
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Mark James Miller, Ph.D.
- Lymphoid tissue dynamics and antigen-presentation during infection, cancer and autoimmunity
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Makedonka Mitreva, Ph.D.
- Next-generation genomic and computational approaches to empower the study of infectious diseases and the human microbiome
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Tae Seok Moon, Ph.D.
- Building the Future with Synthetic Biology
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S. Celeste Morley, M.D., Ph.D.
- Cell biology of the immune system -- understanding how cytoskeletal control of cell motility and adhesion impacts host immunity to infection
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Jennifer A. Philips, M.D., Ph.D.
- Immune Evasion by Mycobacterium tuberculosis
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Gwendalyn J Randolph, Ph.D.
- We focus on inter-organ communication and the transit of cells and molecules out of tissues in healthy and disease states
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Lee Ratner, M.D., Ph.D.
- Molecular biology and pathogenesis of HIV and HTLV
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Courtney Reichhardt, Ph.D.
- Investigating the fundamental biophysical principles of biofilm assembly
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David Rosen, M.D., Ph.D.
- Pathogenesis and host response to Klebsiella pneumoniae infections
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Jai S. Rudra, Ph.D.
- Development of nano-scale biomaterials for engaging the immune system to induce protective antibody and cell-mediated immune responses against diseases
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Liang Shan, Ph.D.
- HIV infection and host immune response in humanized mouse models
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Haina Shin, Ph.D.
- Examining immune responses against viruses that establish persistent infections in their hosts
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David Sibley, Ph.D.
- Cellular and molecular basis of intracellular parasitism by protozoan parasites
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Christina L. Stallings, Ph.D.
- Molecular pathogenesis of Mycobacterium tuberculosis
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Ashley L. Steed, M.D., Ph.D.
- Investigate the genetic and environmental factors that underlie the mechanistic basis for the heterogeneity in outcomes in response to infection
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Joan E. Strassmann, Ph.D.
- We work on social interactions and mutualism using a microbial system so we can study cheating, conflict and cooperation at experimental and genomic levels, within and between species, in particular in social amoebae and their farmed bacteria
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Siobhan Sutcliffe, Ph.D., Sc.M., M.H.S.
- Infectious causes of cancer and chronic diseases
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Yinjie Tang, Ph.D.
- Metabolism analysis and metabolic engineering of environmental microorganisms for biofuel/chemical production
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Phillip I. Tarr, M.D.
- Pathogenic interactions between microbes and the gut
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Heather L. True-Krob, Ph.D.
- Epigenetic regulation of phenotypes by propagation of prions in yeast
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Michael Vahey, Ph.D.
- Biophysical mechanisms of infectious disease
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Steven J. Van Dyken, Ph.D.
- Cytokine-mediated tissue feedback loops that maintain homeostasis, and environmental factors that instigate inflammation and fibrosis.
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Deborah J. Veis (Novack), M.D., Ph.D.
- Role of NF-KB signalling in bone loss, during bone metastasis, arthritis, and osteoporosis
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Joseph P. Vogel, Ph.D.
- Intracellular replication of Legionella pneumophila within macrophages
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David Wang, Ph.D.
- Discovery and Characterization of Novel Viruses
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Gary J. Weil, M.D.
- Research on the biology of filarial nematode parasites
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Timothy A. Wencewicz, Ph.D.
- Antibiotic drug discovery
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Sean P. J. Whelan, Ph.D.
- The Whelan laboratory studies the biology of negative-strand (NS) RNA viruses, divided between two major areas of focus: viral gene expression and viral-host cell interactions.
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Kristine M. Wylie, Ph.D.
- Host-microbe dynamics during pregnancy
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Wayne M. Yokoyama, M.D.
- Host innate immune responses to tumors and pathogens
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Fuzhong Zhang, Ph.D.
- Synthetic biology for advanced biofuels, biomaterials, and chemicals.
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