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Gaya K. Amarasinghe, PhD
- Molecular mechanisms at the host-pathogen interface
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Beau Ances, MD, PhD
- Characterization of Dementia (HIV associated neurocognitive disorders (HAND) and Alzheimer`s Disease (AD) using functional magnetic resonance imaging
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John P. Atkinson, MD
- Complement activation and regulation in innate and adaptive immunity
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Megan T. Baldridge, MD, PhD
- Defining the mechanisms behind and effects of the interactions between commensal bacteria, pathogens and innate immunity
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Rebecca Bart, PhD
- Combining genetics with molecular and computational biology to learn about the mechanisms used by hosts and pathogens to recognize and respond to one another and the environment
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Stephen M. Beverley, PhD
- Molecular genetics of protozoan parasites - virulence and their viruses
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Jacco Boon, PhD
- Emerging viruses
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Arpita Bose, PhD
- Microbial metabolisms and their influence on biogeochemical cycling
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Juliane Bubeck Wardenburg, MD, PhD
- The research in my laboratory is aimed at understanding fundamental principles of the interaction between bacterial pathogens and the human host.
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Yin Cao, ScD, MPH
- Novel genetic, microbial, and lifestyle risk factors for lung and gastrointestinal cancers leveraging large-scale clinical and population-based cohorts with deep genomic and phenotypic data
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Michael G. Caparon, Jr, PhD
- Genetics and virulence of the pathogenetic streptococci
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Douglas L. Chalker, PhD
- Genetic and epigenetic regulation of developmentally programmed DNA rearrangements of Tetrahymena
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Matthew A. Ciorba, MD
- Tryptophan metabolism and probiotic bacteria as modifiers of intestinal cancer and inflammation
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Marco Colonna, MD
- Innate immune responses in infections, autoimmunity and tumors
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David T. Curiel, MD, PhD
- To address the central mandate of gene therapy we engineer adenovirus tropism to allow the achievement of effective gene delivery
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Gautam Dantas, PhD
- (1) Dynamics, ecology, and evolution of antibiotic resistance, (2) Engineering enhanced probiotics to treat GI disorders, (3) Engineering microbial biofuel catalysts
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Michael S. Diamond, MD, PhD
- Innate and Adaptive Host Immunity to Viral Infections
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Mary C. Dinauer, MD, PhD
- Role of leukocyte NADPH oxidase in innate immunity, inflammation, and autoimmunity
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Siyuan Ding, PhD
- Understanding how rotavirus (RV), an important enteric viral pathogen, interacts with the host innate immune system in the small intestine
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Tamara L. Doering, MD, PhD
- Biology and pathogenesis of the pathogenic fungus Cryptococcus neoformans
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Brian T. Edelson, MD, PhD
- Immune cell development and function
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Ali H. Ellebedy, PhD
- Defining the cellular and molecular mechanisms that regulate memory B cell heterogeneity and fate.
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Mario F. Feldman, PhD
- Pathogenesis of multidrug resistant bacteria and biogenesis of bacterial vesicles in the human gut
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Thomas A. Ferguson, PhD
- We are examining the role of the autophagy pathway in the function of the retina and its role in diseases of the eye
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James Fleckenstein, MD
- Molecular investigation of enterotoxigenic Escherichia coli (ETEC)
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Daved H. Fremont, PhD
- Mechanisms of host immunity and viral evasion
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Anthony R. French, PhD, MD
- In vivo NK cell responses during viral infections
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Stephanie A. Fritz, MD, MSCI
- Asking and answering critical questions to guide clinical practice and ameliorate childhood suffering due to staphylococcal disease
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Eric A. Galburt, PhD
- Biophysical studies of transcription initiation in Eukaryotes and Mycobacterial tuberculosis
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Daniel E. Goldberg, MD, PhD
- Biochemistry of malaria
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Jeffrey I. Gordon, MD
- Role of the human gut microbiome in health and disease, notably childhood undernutrition and obesity
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Jeffrey Haspel, MD, PhD
- Understand the impact of time as a biological variable in the development of critical illness such as sepsis, respiratory failure and chronic inflammatory lung disease
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Elizabeth S. Haswell, PhD
- Mechanobiology with a focus on mechanosensitive ion channels
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Jeffrey P. Henderson, MD, PhD
- Biochemical interactions between humans and bacteria in health and disease
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Michael J. Holtzman, MD
- Pathogenesis and new therapeutics for viral infection and post-viral disease
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Henry V. Huang, PhD
- Molecular biology of Sindbis virus; antiviral drug design; monocyte differentiation
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Scott J. Hultgren, PhD
- Interdisciplinary approach combining genetics, genomics, biochemistry, structural biology, high-resolution imaging, animal models, clinical studies and combinatorial chemistry to determine key aspects of bacterial pathogenesis and apply our knowledge to development of new therapeutics.
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David A. Hunstad, MD
- Sex differences, virulence mechanisms, and novel therapeutics in E. coli urinary tract infection
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James W. Janetka, PhD
- The rational structure-based drug design and synthesis for cancer and infectious disease
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Andrew B. Janowski, MD
- Characterization of human diseases associated with novel viral infections
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Andrew L. Kau, MD, PhD
- Understanding the immune-modifying capacity of gastrointestinal and airway microbes through the lens of allergy
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Eynav Klechevsky, PhD
- understand the biology of different human dendritic cells and other myeloid cells as a key for manipulating immune responses in various disease conditions
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Robert G. Kranz, PhD
- Gene regulation and biogenesis of extracellular components in bacteria
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F. Matthew Kuhlmann, MD
- The pre-clinical development of rationally designed Enterotoxigenic E. coli (ETEC) vaccines
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Hrishikesh S. Kulkarni, MD, MSCI
- Modulating the complement system to mitigate pneumonia and acute lung injury
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Barbara N. Kunkel, PhD
- Molecular genetic analysis of disease development in Pseudomonas syringae-Arabidopsis interactions
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Sebla B. Kutluay, PhD
- Human immunodeficiency virus-host interactions
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Jennie Kwon, DO, MSCI
- Dr. Kwon performs clinical and translational research focused on the microbial ecology of multidrug-resistant organisms (MDRO), and their relationship to the fecal microbiome and the microbiome of the built environment.
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George B. Kyei, MB, ChB, PhD
- HIV latency and reservoir maintenance
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Brian Laidlaw, PhD
- Investigating the development of immunological memory in disease states
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Deborah J. Lenschow, MD, PhD
- Antiviral mechanisms of type I interferons and the role of interferons and viruses in autoimmune diseases
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Michele LeRoux, PhD
- We study the molecular arms race between bacteria and phage
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Daisy W. Leung, PhD
- Defining molecular mechanisms at the host-pathogen interface
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Petra Anne Levin, PhD
- Bacterial growth and antibiotic susceptibility
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Fangqiong Ling, PhD
- A computational and experimental lab studying bacterial colonization and transmission at the boundary of built and natural environments and exploring microbiomes as environmental sensors and public health sentinels
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Ta-Chiang Liu, MD, PhD
- Understanding how host genetics and environmental factors interact to shape gut metabolism leading to inflammation
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Carolina B. López, PhD
- The Lopez Lab studies how viruses interact with the body and how defective viruses influence the development of diseases in humans
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Elizabeth Mallott, PhD
- How the environment shapes host-associated microbial communities both within and across species
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Todd P. Margolis, MD, PhD
- The cellular and molecular mechanisms that regulate the establishment and maintenance of latent neuronal infection with herpes simplex virus (HSV).
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William H. McCoy, MD, PhD
- We investigate how host-microbe interactions at epithelial barrier sites impact skin diseases.
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Mark James Miller, PhD
- Lymphoid tissue dynamics and antigen-presentation during infection, cancer and autoimmunity
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Makedonka Mitreva, PhD
- Next-generation experimental, multi-omic and computational approaches to empower the study of infectious diseases and the human microbiome
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Tae Seok Moon, PhD
- Building the Future with Synthetic Biology
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S. Celeste Morley, MD, PhD
- Cell biology of the immune system -- understanding how cytoskeletal control of cell motility and adhesion impacts host immunity to infection
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Anthony Orvedahl, MD, PhD
- Understanding factors that regulate host immune responses to infectious and sterile triggers of severe inflammation
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Slavica Pavlovic-Djuranovic, PhD
- Identifying new targets and possible therapies to treat malaria
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Jennifer A. Philips, MD, PhD
- Immune Evasion by Mycobacterium tuberculosis
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Gwendalyn J Randolph, PhD
- We focus on inter-organ communication and the transit of cells and molecules out of tissues in healthy and disease states
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Lee Ratner, MD, PhD
- Molecular biology and pathogenesis of HIV and HTLV
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Courtney Reichhardt, PhD
- Investigating the fundamental biophysical principles of biofilm assembly
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Felipe Ribeiro, PhD
- Understanding the neuroimmune basis of infectious and non-infectious diseases
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David Rosen, MD, PhD
- Pathogenesis and host response to Klebsiella pneumoniae infections
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Jai S. Rudra, PhD
- Development of nano-scale biomaterials for engaging the immune system to induce protective antibody and cell-mediated immune responses against diseases
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Drew Schwartz, MD, PhD
- Pediatric gut microbiome and immune disruption in serious bacterial infections
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Liang Shan, PhD
- HIV infection and host immune response in humanized mouse models
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David Sibley, PhD
- Cellular and molecular basis of intracellular parasitism by protozoan parasites
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Christina L. Stallings, PhD
- Molecular pathogenesis of Mycobacterium tuberculosis
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Ashley L. Steed, MD, PhD
- Investigate the genetic and environmental factors that underlie the mechanistic basis for the heterogeneity in outcomes in response to infection
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Joan E. Strassmann, PhD
- We work on social interactions and mutualism using a microbial system so we can study cheating, conflict and cooperation at experimental and genomic levels, within and between species, in particular in social amoebae and their farmed bacteria
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Siobhan Sutcliffe, PhD, ScM, MHS
- Infectious causes of cancer and chronic diseases
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Yinjie Tang, PhD
- Metabolism analysis and metabolic engineering of environmental microorganisms for biofuel/chemical production
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Phillip I. Tarr, MD
- Pathogenic interactions between microbes and the gut
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Heather L. True-Krob, PhD
- Epigenetic regulation of phenotypes by propagation of prions in yeast
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Michael Vahey, PhD
- Biophysical mechanisms of infectious disease
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Steven J. Van Dyken, PhD
- Cytokine-mediated tissue feedback loops that maintain homeostasis, and environmental factors that instigate inflammation and fibrosis.
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Deborah J. Veis (Novack), MD, PhD
- The bone microenvironment for cancer and infection
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Joseph P. Vogel, PhD
- Intracellular replication of Legionella pneumophila within macrophages
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David Wang, PhD
- Discovery and Characterization of Novel Viruses
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Timothy A. Wencewicz, PhD
- Antibiotic drug discovery
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Sean P. J. Whelan, PhD
- The Whelan laboratory studies the biology of negative-strand (NS) RNA viruses, divided between two major areas of focus: viral gene expression and viral-host cell interactions.
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Kristine M. Wylie, PhD
- Host-microbe dynamics during pregnancy
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Wayne M. Yokoyama, MD
- Host innate immune responses to tumors and pathogens
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Fuzhong Zhang, PhD
- Synthetic biology for advanced biofuels, biomaterials, and chemicals.
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