Carmen Bergom, M.D., Ph.D.

Associate Professor
Radiation Oncology

Cancer Biology Program
Molecular Genetics and Genomics Program
Molecular Cell Biology Program
Developmental, Regenerative and Stem Cell Biology Program

  • 314-747-1786

  • cbergom@wustl.edu

  • Identification of new targets to improve tumor radiation effectiveness and to protect normal tissues such as the heart from radiation injury

Research Abstract:

I am a physician scientist and an Associate Professor in the Department of Radiation Oncology. I treat breast cancer patients one day per week, and in the remainder of my time I lead a translational research laboratory using unique genetic models to identify new targets to improve tumor radiation effectiveness and to protect normal tissues such as the heart from radiation injury. The major component of my research program is focused specifically on understanding the biology of radiation-induced cardiac changes in order to (1) better prevent, diagnosis, and treat radiation-induced heart disease and (2) better utilize radiation therapy to effectively treat refractory ventricular tachycardia.

Selected Publications:

Sharma G, Jagtap JM, Parchur AK, Gogineni VR, Ran S, BERGOM C, White SB, Flister MJ, Joshi A. Heritable Modifiers of the Tumor Microenvironment influence nanoparticle uptake, distribution and response to therapy. Theranostics. 2020 10:5368-5383. PMID: 32373218

Schlaak RA, Frei A, Fish BL, Harmann L, Gasperetti T, Pipke JL, Sun Y, Rui H, Flister MJ, Gantner BN, BERGOM C. Acquired Immunity is Not Essential for Radiation-Induced Heart Dysfunction But Exerts a Complex Impact on Injury. Cancers. 2020 12:E983. PMID: 32316187

Schlaak RA, Frei A, SenthilKumar G, Tsaih S, Wells C, Mishra J, Flister MJ, Camara AKS, BERGOM C. Differences in Expression of Mitochondrial Complexes Due to Genetic Variants May Alter Sensitivity to Radiation-Induced Cardiac Dysfunction. Front Cardiovasc Med. 2020 7:23 PMID: 32195269.

Schlaak RA, SenthilKumar G, Boerma M, BERGOM C. Advances in Preclinical Research Models of Radiation-Induced Cardiac Toxicity. Cancers. 2020 12:E415. PMID: 32053873

Livingston KL, Schlaak RA, Puckett L, BERGOM C. The Role of Mitochondrial Dysfunction in Radiation-Induced Heart Disease: From Bench to Bedside. Front Cardiovasc Med. 2020 7:20. PMID: 3214269

Last Updated: 12/15/2020 11:26:23 AM

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