Ariella Coler-Reilly

Program: Molecular Cell Biology

Current advisor: Roberto Civitelli, MD

Undergraduate university: University of California-Berkeley, 2011

Enrollment year: 2017

Research summary
Unbiased interdisciplinary investigation of age-related genes

Under the guidance of Dr. Roberto Civitelli, I am investigating the role of genes consistently differentially expressed with age. While these genes are the subject of innumerable studies comparing tissues from young and old donors, such studies only describe associations, failing to distinguish drivers of aging from compensatory geroprotective responses and meaningless downstream effects. To address this critical flaw, we developed a workflow to synthesize these data, pinpoint the most consistent expression patterns, and conduct functional experiments to characterize how modulating each pattern affects lifespan and cellular senescence.

Graduate publications
Mazi PB, Sahrmann JM, Olsen MA, Coler-Reilly A, Rauseo AM, Pullen M, Zuniga-Moya JC, Powderly WG, Spec A. 2023 The Geographic Distribution of Dimorphic Mycoses in the United States for the Modern Era. Clin Infect Dis, 76(7):1295-1301. PMCID: PMC10319749

Coler-Reilly A, Graef ER, Kim AHJ, Liew JW, Putman MS, Sattui SE, Young KJ, Sparks JA. 2022 Social Media for Research Discourse, Dissemination, and Collaboration in Rheumatology. Rheumatol Immunol Res, 3(4):169-79. PMCID: PMC9984924