Drake Jensen

Program: Computational and Molecular Biophysics

Current advisor: Eric A. Galburt, PhD

Undergraduate university: Southern Illinois University-Edwardsville, 2013

Enrollment year: 2015

Research summary
mechanisms of transcription initiation in mycobacteria

Graduate publications
Chadda A, Jensen D, Tomko EJ, Ruiz Manzano A, Nguyen B, Lohman TM, Galburt EA. 2022 Mycobacterium tuberculosis DNA repair helicase UvrD1 is activated by redox-dependent dimerization via a 2B domain cysteine. Proc Natl Acad Sci USA, 119(8):e2114501119.

Prusa J, Zhu DX, Flynn AJ, Jensen D, Manzano AR, Galburt EA, Stallings CL. 2022 Molecular dissection of RbpA-mediated regulation of fidaxomicin sensitivity in mycobacteria. J Biol Chem, 298(4):101752.

Jensen D, Galburt EA. 2021 The Context-Dependent Influence of Promoter Sequence Motifs on Transcription Initiation Kinetics and Regulation. J Bacteriol, 203(8):e00512-20.

Jensen D, Manzano AR, Rammohan J, Stallings CL, Galburt EA. 2019 CarD and RbpA modify the kinetics of initial transcription and slow promoter escape of the Mycobacterium tuberculosis RNA polymerase. Nucleic Acids Res, ():pii: gkz449.

Prusa J, Jensen D, Santiago-Collazo G, Pope SS, Garner AL, Miller JJ, Ruiz Manzano A, Galburt EA, Stallings CL. 2018 Domains within RbpA Serve Specific Functional Roles That Regulate the Expression of Distinct Mycobacterial Gene Subsets. J Bacteriol, 200(13):pii: e00690-17.

Garner AL, Rammohan J, Huynh JP, Onder LM, Chen J, Bae B, Jensen D, Weiss LA, Manzano AR, Darst SA, Campbell EA, Nickels BE, Galburt EA, Stallings CL. 2017 Effects of Increasing the Affinity of CarD for RNA Polymerase on Mycobacterium tuberculosis Growth, rRNA Transcription, and Virulence. J Bacteriol, 199(4):pii: e00698-16.