Jhullian Alston

Program: Biochemistry Biophysics and Structural Biology

Current advisor: Andrea Soranno, PhD

Undergraduate university: University of Maryland-Baltimore County, 2017

Enrollment year: 2017

Research summary
Combining experimental and computational methods to understand the role of intrinsically disordered regions in telomere assembly and dysregulation

Combining experimental and computational methods to understand the role of intrinsically disordered regions in telomere assembly and dysregulation.

Graduate publications
Alston JJ, Soranno A. 2023 Condensation Goes Viral: A Polymer Physics Perspective. J Mol Biol, ():Online ahead of print. PMCID:

Alston JJ, Ginell GM, Soranno A, Holehouse AS. 2023 The Analytical Flory Random Coil Is a Simple-to-Use Reference Model for Unfolded and Disordered Proteins. J Phys Chem B, 127(21):4746-60. PMCID:

Alston JJ, Cubuk J, Incicco J, Stuchell-Brereton MD, Hall KB, Holehouse AS, Soranno A. 2023 Combining simulations and single-molecule fluorescence spectroscopy to understand SARS-CoV-2 nucleocapsid protein RNA interaction. Biophys J, 122(3):202a. PMCID: PMC9912775

Cubuk J, Incicco J, Alston JJ, Hall KB, Stuchell-Brereton MD, Soranno A. 2023 Single-molecule spectroscopy of the SARS-CoV-2 nucleocapsid protein. Biophys J, 122(3):200a. PMCID: PMC9912915

Cubuk J, Alston JJ, Incicco JJ, Singh S, Stuchell-Brereton MD, Ward MD, Zimmerman MI, Vithani N, Griffith D, Wagoner JA, Bowman GR, Hall KB, Soranno A, Holehouse AS. 2021 The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA. Nat Commun, 12(1):1936. PMCID: PMC8007728

Alston JJ, Soranno A, Holehouse AS. 2021 Integrating single-molecule spectroscopy and simulations for the study of intrinsically disordered proteins. Methods, 193():116-35. PMCID: PMC8713295