Michael Strickland

Program: Neurosciences

Current advisor: David M. Holtzman, MD

Undergraduate university: University of Florida, 2017

Enrollment year: 2017

Research summary
Investigating the role of ApoE in Alzheimer’s Disease pathogenesis

Graduate publications
Gratuze M, Chen Y, Parhizkar S, Jain N, Strickland MR, Serrano JR, Colonna M, Ulrich JD, Holtzman DM. 2021 Activated microglia mitigate Aβ-associated tau seeding and spreading. J Exp Med, 218(8):e20210542.

Kober DL, Stuchell-Brereton MD, Kluender CE, Dean HB, Strickland MR, Steinberg DF, Nelson SS, Baban B, Holtzman DM, Frieden C, Alexander-Brett J, Roberson ED, Song Y, Brett TJ. 2020 Functional insights from biophysical study of TREM2 interactions with apoE and Aβ 1-42. Alzheimers Dement, ():Online ahead of print.

Chen Y, Strickland MR, Soranno A, Holtzman DM. 2020 Apolipoprotein E: Structural Insights and Links to Alzheimer Disease Pathogenesis. Neuron, ():S0896-6273(20)30776-5.

Strickland MR, Holtzman DM. 2019 Dr. Jekyll and Mr. Hyde: ApoE explains opposing effects of neuronal LRP1. J Clin Invest, 129(3):969-971.