Biomedical Informatics and Data Science

Program affiliation
Biomedical Informatics and Data Science
Cancer Biology
Molecular Cell Biology
Immunology

Research summary
Development of personalized medicine strategies for cancer using genomic technologies

Key words
bioinformatics, machine learning, cancer, genomics, immunogenomics, precision oncology

Program affiliation
Biomedical Informatics and Data Science
Human and Statistical Genetics
Computational and Systems Biology

Research summary
Statistical genetics and bioinformatics, high-dimensional data analysis and complex systems modeling, developing novel methodologies for detecting complex disease genes and characterizing their function

Key words
genetic epidemiology, statistical genetics

Program affiliation
Human and Statistical Genetics
Ecology and Evolutionary Biology
Biomedical Informatics and Data Science

Research summary
Genetic studies of alcoholism, smoking and drug dependence, depression, suicidality and anxiety disorders, personality disorders, and methodological research in genetic epidemiology

Key words
substance abuse, development, modeling, psychiatry, quantitative genetics

Program affiliation
Molecular Cell Biology
Cancer Biology
Biochemistry Biophysics and Structural Biology
Biomedical Informatics and Data Science

Research summary
Redox biochemistry in cell signaling and disease, Proteomics

Key words
proteomics, post-translational modification, cysteine, redox, mass spectrometry, oxidation

Program affiliation
Neurosciences
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Biomedical Informatics and Data Science

Research summary
Molecular, cellular and circuit analysis of circadian rhythms in mammals

Key words
neurobiology, behavior, imaging, circadian rhythm, glia, brain cancer, potassium channels, neuropeptides, astrocytes, glioblastoma, cancer, developmental biology, computational modeling

Program affiliation
Neurosciences
Computational and Systems Biology
Biomedical Informatics and Data Science

Research summary
Understanding the learning mechanisms of the brain from theoretical and computational perspectives

Key words
Computational neuroscience, Synaptic plasticity, Olfaction, Deep learning

Program affiliation
Biomedical Informatics and Data Science
Molecular Genetics and Genomics

Research summary

Key words
shared decision making, health equity, implementation science

Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Biomedical Informatics and Data Science

Research summary
Interactions between the nervous and genitourinary systems during development, molecular basis for heterogeneity in progenitors and their lineage commitments in the GU tract, injury and regeneration using animal models, mechanisms of malformations using organoids from iPSCs

Key words
cell fate, gene expression, genomics, disease models, growth factor signaling, kidney, bladder, innervation, stem cells, organogenesis, nervous system development, birth defects

Program affiliation
Biomedical Informatics and Data Science
Cancer Biology

Research summary
Development of novel statistical methods for precision medicine

Key words
Biostatistics; Image analysis; Dynamic risk prediction; Multistate models

Program affiliation
Computational and Systems Biology
Molecular Genetics and Genomics
Biomedical Informatics and Data Science
Human and Statistical Genetics

Research summary
We use human genetic, functional genomic, and bioinformatic approaches to understand the consequence of genetic variants underlying diseases

Key words
Functional genomics, bioinformatics, human genetics, data science, rare diseases, structural variation