Molecular Microbiology and Microbial Pathogenesis
Carolina Lopez, PhD
Professor and BJC Investigator
- Email: clopezzalaquett@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology
Research summary
The Lopez Lab studies how viruses interact with the body and how defective viruses influence the development of diseases in humans
Key words
virus, respiratory syncytial virus, Sendai virus, innate immunity, antiviral immunity
Elizabeth Mallott, PhD
Assistant Professor
- Email: mallott@wustl.edu
Program affiliation
Ecology and Evolutionary Biology
Plant and Microbial Biosciences
Molecular Microbiology and Microbial Pathogenesis
Research summary
How the environment shapes host-associated microbial communities both within and across species
Key words
Gut microbiome, nonhuman primates, environmental health
Todd Margolis, MD, PhD
Alan A and Edith L Wolff Distinguished Professor and Head of the Department of Ophthalmology and Visual Sciences
- Email: margolist@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Research summary
The cellular and molecular mechanisms that regulate the establishment and maintenance of latent neuronal infection with herpes simplex virus (HSV).
Key words
William McCoy, MD, PhD
Assistant Professor
- Email: mccoyw@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology
Biochemistry Biophysics and Structural Biology
Research summary
We investigate how host-microbe interactions at epithelial barrier sites impact skin diseases.
Key words
acne, microbiome, cryogenic electron microscopy, cryoEM, crystallography, Cutibacterium acnes, melanoma, immune checkpoint inhibitor, ICI
Mark Miller, PhD
Associate Professor
- Email: mmiller23@wustl.edu
Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Research summary
Lymphoid tissue dynamics and antigen-presentation during infection, cancer and autoimmunity
Key words
imaging, inflammation, pathogenesis, mathematical modeling, multi-photon microscopy
Makedonka Mitreva, PhD
Professor
- Email: mmitreva@wustl.edu
Program affiliation
Computational and Systems Biology
Molecular Genetics and Genomics
Molecular Microbiology and Microbial Pathogenesis
Biochemistry Biophysics and Structural Biology
Research summary
Next-generation experimental, multi-omic and computational approaches to empower the study of infectious diseases and the human microbiome
Key words
Genomics of Infectious Diseases, Helminth Genomics, Human Metagenomics
S. Celeste Morley, MD, PhD
Associate Professor
- Email: morleys@wustl.edu
Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Molecular Cell Biology
Research summary
Cell biology of the immune system -- understanding how cytoskeletal control of cell motility and adhesion impacts host immunity to infection
Key words
actin cytoskeleton, L-plastin, T cell, B cell, lymphocyte motility, pneumococcal pneumonia,
Philip Mudd, MD, PhD
Assistant Professor
- Email: pmudd@wustl.edu
Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Research summary
Our laboratory studies the characteristics and function of human T cells that recognize viral pathogens following vaccination or during acute infection.
Key words
translational research, human immunology, T cell, viral infection, influenza
Anthony Orvedahl, MD, PhD
Assistant Professor
- Email: aorvedahl@wustl.edu
Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Research summary
Understanding factors that regulate host immune responses to infectious and sterile triggers of severe inflammation
Key words
Slavica Pavlovic Djuranovic, PhD
Assistant Professor
- Email: spavlov@wustl.edu
Program affiliation
Molecular Cell Biology
Molecular Microbiology and Microbial Pathogenesis
Biochemistry Biophysics and Structural Biology
Molecular Genetics and Genomics
Research summary
Identifying new targets and possible therapies to treat malaria
Key words
malaria, mRNA surveillance, drug discovery