Molecular Microbiology and Microbial Pathogenesis
Fangqiong Ling, PhD
Associate Professor
- Email: fangqiong@wustl.edu
Program affiliation
Computational and Systems Biology
Molecular Microbiology and Microbial Pathogenesis
Plant and Microbial Biosciences
Research summary
A computational and experimental lab studying bacterial colonization and transmission at the boundary of built and natural environments and exploring microbiomes as environmental sensors and public health sentinels
Key words
Ta-Chiang Liu, MD, PhD
Associate Professor
- Email: ta-chiang.liu@wustl.edu
Program affiliation
Immunology
Developmental Regenerative and Stem Cell Biology
Molecular Microbiology and Microbial Pathogenesis
Research summary
Understanding how host genetics and environmental factors interact to shape gut metabolism leading to inflammation
Key words
Carolina Lopez, PhD
Professor and BJC Investigator
- Email: clopezzalaquett@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology
Research summary
The Lopez Lab studies how viruses interact with the body and how defective viruses influence the development of diseases in humans
Key words
virus, respiratory syncytial virus, Sendai virus, innate immunity, antiviral immunity
William McCoy, MD, PhD
Assistant Professor
- Email: mccoyw@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology
Biochemistry Biophysics and Structural Biology
Research summary
We investigate how host-microbe interactions at epithelial barrier sites impact skin diseases.
Key words
acne, microbiome, cryogenic electron microscopy, cryoEM, crystallography, Cutibacterium acnes, melanoma, immune checkpoint inhibitor, ICI
Makedonka Mitreva, PhD
Professor
- Email: mmitreva@wustl.edu
Program affiliation
Computational and Systems Biology
Molecular Genetics and Genomics
Molecular Microbiology and Microbial Pathogenesis
Biochemistry Biophysics and Structural Biology
Research summary
Next-generation experimental, multi-omic and computational approaches to empower the study of infectious diseases and the human microbiome
Key words
Genomics of Infectious Diseases, Helminth Genomics, Human Metagenomics
S. Celeste Morley, MD, PhD
Associate Professor
- Email: morleys@wustl.edu
Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Molecular Cell Biology
Research summary
Cell biology of the immune system -- understanding how cytoskeletal control of cell motility and adhesion impacts host immunity to infection
Key words
actin cytoskeleton, L-plastin, T cell, B cell, lymphocyte motility, pneumococcal pneumonia,
Philip Mudd, MD, PhD
Assistant Professor
- Email: pmudd@wustl.edu
Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Research summary
Our laboratory studies the characteristics and function of human T cells that recognize viral pathogens following vaccination or during acute infection.
Key words
translational research, human immunology, T cell, viral infection, influenza
Anthony Orvedahl, MD, PhD
Assistant Professor
- Email: aorvedahl@wustl.edu
Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Research summary
Understanding factors that regulate host immune responses to infectious and sterile triggers of severe inflammation
Key words
Jacqueline Payton, MD, PhD
Associate Professor
- Email: jpayton@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Cancer Biology
Biomedical Informatics and Data Science
Molecular Microbiology and Microbial Pathogenesis
Research summary
Epigenomic aberrations in B cell lymphomas and their impact on gene regulation
Key words
epigenomics, cancer, lymphoma, histone, informatics, genomics, gene regulation