Molecular Microbiology and Microbial Pathogenesis
Eynav Klechevsky, PhD
Associate Professor
- Email: eklechevsky@wustl.edu
Program affiliation
Immunology
Cancer Biology
Molecular Microbiology and Microbial Pathogenesis
Computational and Systems Biology
Research summary
understand the biology of different human dendritic cells and other myeloid cells as a key for manipulating immune responses in various disease conditions
Key words
Human Immunology, Dendritic Cells, Tumor Immunology, immune dysfunctions, Vaccines
Dmitri Kotov, PhD
Assistant Professor
- Email: kotov@wustl.edu
Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Computational and Systems Biology
Research summary
My lab works on the host immune response to Mycobacterium tuberculosis. We use mouse models that mimic key aspects of human disease to gain a mechanistic understanding of the host response allowing for the identification of novel targets for host-directed therapies.
Key words
Mycobacterium tuberculosis, innate immunology, macrophages, neutrophils, dendritic cells
Barbara Kunkel, PhD
Professor
- Email: kunkel@wustl.edu
Program affiliation
Plant and Microbial Biosciences
Molecular Microbiology and Microbial Pathogenesis
Molecular Genetics and Genomics
Research summary
Molecular genetic analysis of disease development in Pseudomonas syringae-Arabidopsis interactions
Key words
plant-microbe interactions, bacterial pathogenesis, auxin, IAA, Type III effector protein, genetics, plant biology
Sebla Kutluay, PhD
Associate Professor
- Email: kutluay@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Plant and Microbial Biosciences
Biochemistry Biophysics and Structural Biology
Computational and Systems Biology
Research summary
Human immunodeficiency virus-host interactions
Key words
Brian Laidlaw, PhD
Assistant Professor
- Email: brian.laidlaw@wustl.edu
Program affiliation
Immunology
Computational and Systems Biology
Molecular Microbiology and Microbial Pathogenesis
Research summary
Investigating the development of immunological memory in disease states
Key words
B cells, immunological memory, germinal center, virus, allergy
Janet Lee, MD
Selma and Herman Seldin Distinguished Professor of Medicine
- Email: ljanet@wustl.edu
Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Research summary
Key words
Deborah Lenschow, MD, PhD
John S. Daniels Professor
- Email: dlenschow@wustl.edu
Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Research summary
Antiviral mechanisms of type I interferons and the role of interferons and viruses in autoimmune diseases
Key words
host-pathogen interactions, immunology, innate immunity, interferons, pathogenesis, virology, autoimmune disease, lupus
Michele LeRoux, PhD
Assistant Professor
- Email: mleroux@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Plant and Microbial Biosciences
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
We study how bacterial defend themselves from their viral predators, bacteriophage.
Key words
bacteria, phage, bacteriophage, virus
Daisy Leung, PhD
Professor
- Email: dwleung@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Biochemistry Biophysics and Structural Biology
Research summary
Defining molecular mechanisms at the host-pathogen interface
Key words
Petra Levin, PhD
George William and Irene Koechig Freiberg Professor
- Email: plevin@wustl.edu
Program affiliation
Plant and Microbial Biosciences
Molecular Microbiology and Microbial Pathogenesis
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Research summary
Bacterial growth and antibiotic susceptibility
Key words
Bacterial, growth size, antibiotics, tolerance, antibiotic resistance, systems biology, cytoskeleton, biochemistry, microbiology, microscopy