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Douglas Covey, PhD

Professor

Program affiliation
Biochemistry Biophysics and Structural Biology
Neurosciences

Research summary
Medicinal chemistry of steroids

Key words
cholesterol, ion channel, medicinal chemistry, neurobiology, pharmacology, steroids

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Meaghan Creed, PhD

Associate Professor

Program affiliation
Neurosciences

Research summary
Leveraging synaptic physiology to treat addiction and affective symptoms of pain

Key words
electrophysiology, deep brain stimulation, dopamine, basal ganglia, reward and aversion, addiction, genetics, pharmacology, optogenetics, pain

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Carlos Cruchaga, PhD

Barbara Burton & Reuben Morriss III Professor

Program affiliation
Human and Statistical Genetics
Neurosciences
Biomedical Informatics and Data Science
Molecular Genetics and Genomics

Research summary
The goal of my lab is to understand the biology of neurodegeneration by using high-dimensional omic data and functional genomic approaches.

Key words
Neurodegeneration, Alzheimer, genetics, genomics, proteomics, system biology, molecular phenotyping, functional genomics

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Jianmin Cui, PhD

Professor on the Spencer T. Olin Endowment

Program affiliation
Biochemistry Biophysics and Structural Biology
Neurosciences

Research summary
Molecular basis of bioelectricity and related diseases in nervous and cardiovascular systems; ion channel function and modulation; discovery of drugs that target ion channels

Key words
allosteric regulation, calcium, drug mechanisms, epilepsy, ion channel, structure-function analysis

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Joseph Culver, PhD

Sherwood Moore Professor

Program affiliation
Neurosciences

Research summary
Non-invasive optical measurements for both functional- and molecular- biological imaging

Key words

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Yifan Dai, PhD

Assistant Professor

Program affiliation
Biochemistry Biophysics and Structural Biology
Neurosciences
Molecular Microbiology and Microbial Pathogenesis
Molecular Cell Biology

Research summary
My lab aims to establish the fundamental principles of intracellular physical chemistry and electrochemical functions of macromolecular complexes, and design synthetic proteins as therapeutics for condensate-dependent diseases.

Key words
molecular biology; physical chemistry; biochemistry; biophysics; synthetic biology; electrochemistry; phase transition; condensates

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Mai Dang, MD, PhD

Assistant Professor

Program affiliation
Neurosciences
Cancer Biology
Immunology

Research summary

Key words

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Albert Davis, MD, PhD

Assistant Professor

Program affiliation
Neurosciences
Molecular Cell Biology
Immunology
Biochemistry Biophysics and Structural Biology

Research summary
Understanding the molecular and cellular mechanisms of protein aggregation and neurodegeneration in Parkinson disease and dementia with Lewy bodies

Key words

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Aaron DiAntonio, MD, PhD

Professor

Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology

Research summary
Neural circuits in development and disease

Key words
axon regeneration, axon degeneration, neurodegeneration, glia, neuronal development and differentiation, neuroinflammation, neuroimmunology, synapse biology, drug screens, metabolism

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Patricia Dickson, MD

Centennial Professor

Program affiliation
Molecular Genetics and Genomics
Neurosciences

Research summary
Developing therapies and studying the impact of lysosomal storage disorders in animal models and in trials

Key words