Neurosciences

Program affiliation
Biochemistry Biophysics and Structural Biology
Neurosciences
Molecular Cell Biology

Research summary
Mechanisms and Design Principles of Ion Channel Function and Gating

Key words

Program affiliation
Neurosciences

Research summary
My research focuses on investigating system biological immune responses in neurodegenerative disease. Using various PET radiotracers, the lab works to detect brain and whole-body inflammation and links these imaging biomarkers to underlying blood and tissue cellular and molecular readouts using appropriate techniques.

Key words
Molecular imaging, neuroimmune interactions, translational research, myeloid cell responses, neurological and neurodegenerative diseases

Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Neurosciences

Research summary
Characterizing and dissecting the molecular mechanisms of opioid receptor signaling

Key words
GPCRs, Analgesics, Side effects, opioid receptors, opioids, opioid alternatives

Program affiliation
Molecular Cell Biology
Neurosciences
Cancer Biology

Research summary
Advances the field of NeuroSonics by integrating breakthroughs in neuroscience and ultrasonics to deepen our understanding of brain function and transform the diagnosis and treatment of neurological diseases.

Key words
Brain, neuroscience, cancer biology, imaging, ultrasound

Program affiliation
Molecular Genetics and Genomics
Developmental Regenerative and Stem Cell Biology
Neurosciences

Research summary
Molecular mechanisms regulating photoreceptor gene expression in healthy and diseased retinas

Key words
Gene expression regulation, transcription factors, epigenetic regulators, photoreceptor development and degeneration, mouse models, gene therapy

Program affiliation
Neurosciences
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Molecular Genetics and Genomics
Computational and Systems Biology

Research summary
Understanding the function of neuromodulators and sleep through the spatiotemporal dynamics of molecular signals

Key words
neuromodulator, sleep, dynamics, sensors, actuators, signaling, G protein coupled receptors, imaging, microscopy, learning, plasticity, engineering

Program affiliation
Biochemistry Biophysics and Structural Biology
Neurosciences
Molecular Cell Biology

Research summary
I am interested in the structure and function of neuronal ligand-gated ion channels, and the mechanism of channel modulation by endogenous lipids or exogenous drugs such as general anesthetics.

Key words

Program affiliation
Neurosciences
Biochemistry Biophysics and Structural Biology

Research summary
The interface between systems and control engineering, neuroscience and neural medicine

Key words
Control of neural dynamics; Biophysical modeling of multiscale brain networks;

Program affiliation
Neurosciences

Research summary
Relationship between synaptic activtity and amyloid-beta metabolism in Alzheimer`s disease

Key words
Alzheimer’s disease, drug and target discovery, endocytosis, in vivo microdialysis, synaptic transmission

Program affiliation
Developmental Regenerative and Stem Cell Biology
Neurosciences
Molecular Genetics and Genomics

Research summary
Genetic and epigenetic control of retinal development and retinal cell fate specification

Key words