Neurosciences

Program affiliation
Neurosciences
Molecular Genetics and Genomics
Computational and Systems Biology

Research summary
Understanding the role of endogenous opioids in affective neuroscience and metabolic homeostasis

Key words
reward, valence, opioid, motivation, metabolism, diabetes

Program affiliation
Neurosciences
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Biochemistry Biophysics and Structural Biology

Research summary
Cellular, Molecular and Epigenetic control of axon regeneration

Key words
axon regeneration, nerve injury, epigenetic, transcription, glia biology, neuroimmune mechanisms, spinal cord injury, optic nerve injury

Program affiliation
Neurosciences
Computational and Systems Biology

Research summary
Exploring neuromorphic architectures using silicon and biological neurons; Novel self-powered neural recording systems

Key words

Program affiliation
Neurosciences
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Computational and Systems Biology

Research summary

Key words

Program affiliation
Neurosciences
Biomedical Informatics and Data Science
Computational and Systems Biology
Biochemistry Biophysics and Structural Biology

Research summary
We develop innovative computational analytical methodologies for studying brain health and neuropsychiatric and neurological disorders such as schizophrenia and Alzheimer’s. The lab employs AI and multimodal neuroimaging — including PET, MRI/fMRI, and EEG — as well as behavioral, clinical and genetic approaches for designing predictive models, identifying disease heterogeneity dimensions and facilitating precision medicine

Key words
Neuroimaging, neurophysics, neuroinformatics, computational neuroscience, clinical research, artificial intelligence, machine learning, deep learning, big data, neuropsychiatric and neurological disorders, neuroimaging-genetics, neuroimaging-behavior

Program affiliation
Biochemistry Biophysics and Structural Biology
Neurosciences
Molecular Cell Biology

Research summary
Mechanisms and Design Principles of Ion Channel Function and Gating

Key words

Program affiliation
Neurosciences

Research summary
My research focuses on investigating system biological immune responses in neurodegenerative disease. Using various PET radiotracers, the lab works to detect brain and whole-body inflammation and links these imaging biomarkers to underlying blood and tissue cellular and molecular readouts using appropriate techniques.

Key words
Molecular imaging, neuroimmune interactions, translational research, myeloid cell responses, neurological and neurodegenerative diseases

Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Neurosciences

Research summary
Characterizing and dissecting the molecular mechanisms of opioid receptor signaling

Key words
GPCRs, Analgesics, Side effects, opioid receptors, opioids, opioid alternatives

Program affiliation
Molecular Genetics and Genomics
Developmental Regenerative and Stem Cell Biology
Neurosciences

Research summary
Molecular mechanisms regulating photoreceptor gene expression in healthy and diseased retinas

Key words
Gene expression regulation, transcription factors, epigenetic regulators, photoreceptor development and degeneration, mouse models, gene therapy

Program affiliation
Neurosciences
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Molecular Genetics and Genomics
Computational and Systems Biology

Research summary
Understanding the function of neuromodulators and sleep through the spatiotemporal dynamics of molecular signals

Key words
neuromodulator, sleep, dynamics, sensors, actuators, signaling, G protein coupled receptors, imaging, microscopy, learning, plasticity, engineering