Faculty

Program affiliation
Neurosciences
Molecular Genetics and Genomics
Molecular Cell Biology

Research summary
Cellular and molecular pathogenesis of Alzheimer's disease

Key words
Alzheimer's disease, neurodegeneration, amyloid, tau, mouse models, risk factors, lysosome, gene therapy

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Neurosciences

Research summary
Characterization of human diseases associated with novel viral infections

Key words
Virology, microbiology, pathogen discovery, host-virus interactions, viral immunity, astroviruses, encephalitis, myocarditis, viral RNA structures

Program affiliation
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology

Research summary
we study the molecular mechanisms that regulate the architecture, dimensions and dynamics of actin filament networks, and tune them to support essential cellular functions including cell migration, intracellular trafficking and cytokinesis.

Key words
actin cytoskeleton, microtubule, single molecule, live cell imaging, protein transport, Golgi, confocal microscopy

Program affiliation
Molecular Cell Biology
Molecular Genetics and Genomics

Research summary

Key words

Program affiliation
General

Research summary
Using single-cell sequencing and spatial imaging to learn about cancer initiation, progression and treatment.

Key words
scRNA, spatial transcriptomics, computational oncology, sequencing

Program affiliation
Plant and Microbial Biosciences
Biochemistry Biophysics and Structural Biology

Research summary
Exploring regulatory networks in metabolism - structural biology and biochemistry of plants and microbes

Key words
biochemistry, enzymology, plant biology, protein engineering, protein structure, structural biology

Program affiliation
Biomedical Informatics and Data Science
Cancer Biology

Research summary
Development of novel statistical methods for precision medicine

Key words
Biostatistics; Image analysis; Dynamic risk prediction; Multistate models

Program affiliation
Computational and Systems Biology
Molecular Genetics and Genomics
Biomedical Informatics and Data Science
Human and Statistical Genetics

Research summary
We use human genetic, functional genomic, and bioinformatic approaches to understand the consequence of genetic variants underlying diseases

Key words
Functional genomics, bioinformatics, human genetics, data science, rare diseases, structural variation

Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Cancer Biology

Research summary
I am interested in precursor conditions or metaplasias in the stomach and esophagus (i.e Barrett’s esophagus) as these lesions are key to understanding the formation of gastroesophageal adenocarcinomas.

Key words
Intestinal metaplasia, gastroesophageal cancer, Barrett's esophagus, GI development, Organoids

Program affiliation
Immunology
Cancer Biology

Research summary
Novel immunotherapeutic strategies to treat solid tumors

Key words