Biochemistry Biophysics and Structural Biology
Kendall Blumer, PhD
Professor
- Email: kblumer@wustl.edu
Program affiliation
Molecular Cell Biology
Cancer Biology
Biochemistry Biophysics and Structural Biology
Research summary
Tumor cell biology, signal transduction, and drug development
Key words
cancer, signal transduction, molecular pharmacology, autophagy, metabolism, drug development
Ron Bose, MD, PhD
Associate Professor
- Email: rbose@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
Genomics and Cell Signaling in Breast Cancer
Key words
cancer, genomics, organoids, 3D culture, receptor tyrosine kinase, signal transduction, next-generation sequencing, targeted therapy of cancer
Thomas Brett, PhD
Associate Professor
- Email: tbrett@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Immunology
Research summary
The molecular basis of lung diseases and drug development using structural biology tools
Key words
biophysics, crystallography, molecular medicine, asthma, mucosal immunology, Alzheimer`s disease, endocytosis, receptor trafficking, structural biology, structure based drug design
Jeffrey Brown, MD PhD
Assistant Professor
- Email: brownjw@wustl.edu
Program affiliation
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Developmental Regenerative and Stem Cell Biology
Research summary
Key words
Peter Burgers, PhD
Professor
- Email: burgers@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Genetics and Genomics
Molecular Cell Biology
Research summary
Molecular Biology of DNA replication and damage response in yeast and human
Key words
Cell cycle, DNA damage response, DNA replication, Checkpoints, Mutagenesis, DNA repair, yeast
Valeria Cavalli, PhD
Robert E. and Louise F. Dunn Professor of Biomedical Research
- Email: cavalli@wustl.edu
Program affiliation
Neurosciences
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
Cellular, Molecular and Epigenetic control of axon regeneration
Key words
axon regeneration, nerve injury, epigenetic, transcription, glia biology, neuroimmune mechanisms, spinal cord injury, optic nerve injury
Alexander Chamessian, MD PhD
Assistant Professor
- Email: a.chamessian@wustl.edu
Program affiliation
Neurosciences
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Computational and Systems Biology
Research summary
Key words
Ganesh Chand, PhD
Assistant Professor
- Email: gchand@wustl.edu
Program affiliation
Neurosciences
Biomedical Informatics and Data Science
Computational and Systems Biology
Biochemistry Biophysics and Structural Biology
Research summary
We develop innovative computational analytical methodologies for studying brain health and neuropsychiatric and neurological disorders such as schizophrenia and Alzheimer’s. The lab employs AI and multimodal neuroimaging — including PET, MRI/fMRI, and EEG — as well as behavioral, clinical and genetic approaches for designing predictive models, identifying disease heterogeneity dimensions and facilitating precision medicine
Key words
Neuroimaging, neurophysics, neuroinformatics, computational neuroscience, clinical research, artificial intelligence, machine learning, deep learning, big data, neuropsychiatric and neurological disorders, neuroimaging-genetics, neuroimaging-behavior