Faculty

Program affiliation
General

Research summary
Pathophysiology and novel therapies for lysosomal storage diseases

Key words
gene therapy, hematopoiesis, metabolism, neurobiology, neurodegeneration, stem cells

Program affiliation
Molecular Cell Biology

Research summary
Aspects of sexual reproduction that involve membrane excitability and control of membrane voltage in spermatozoa, which are essential for the sperm to fertilize the egg

Key words
male fertility, ion channels, sperm physiology,

Program affiliation
Molecular Cell Biology
Molecular Genetics and Genomics
Biochemistry Biophysics and Structural Biology

Research summary
My laboratory uses genetics, cell biology and systems biology approaches to study how the cell regulates its metabolic programs and how dysfunctions in these programs lead to neurological disease

Key words

Program affiliation
General

Research summary
Molecular basis of normal and abnormal development

Key words
development, bone biology, stem cell, heparan sulfate, cell signaling

Program affiliation
Ecology and Evolutionary Biology
Plant and Microbial Biosciences

Research summary
Evolutionary genetics and systematics of plants

Key words
evolution, population genetics, plant biology

Program affiliation
General

Research summary

Key words

Program affiliation
Molecular Genetics and Genomics
Developmental Regenerative and Stem Cell Biology

Research summary
Control of germline stem cells and meiotic development in C. elegans

Key words
germ cells, C. elegans, genetics, development, functional genomics

Program affiliation
Molecular Cell Biology
Neurosciences
Developmental Regenerative and Stem Cell Biology

Research summary
Interactions between the nervous system and the skeleton

Key words
bone, diabetes, nerve, neuropathy, neuroskeletal biology, obesity, metabolism, adipose tissue, adipocyte, high-resolution imaging, advanced quantification, RNAseq, regeneration, healing

Program affiliation
Immunology

Research summary
My research is focused on understanding the role of liver macrophages in metabolic liver disease and heart failure. Using pre-clinical models and human samples we seek to discover novel pathways to modulate immune function for patients with cardiometabolic disease and cardiogenic liver disease..

Key words
macrophages, tissue injury, infection, diabetes, heart failure, metabolic liver disease

Program affiliation
Neurosciences

Research summary
Our laboratory develops and validates blood and CSF biomarkers for Alzheimer disease and related disorders

Key words
biomarkers, Alzheimer disease, dementia, diagnostic tests, cognition