Faculty

Program affiliation
Ecology and Evolutionary Biology
Plant and Microbial Biosciences

Research summary
Evolutionary genetics and systematics of plants

Key words
evolution, population genetics, plant biology

Program affiliation
General

Research summary

Key words

Program affiliation
Molecular Genetics and Genomics
Developmental Regenerative and Stem Cell Biology

Research summary
Control of germline stem cells and meiotic development in C. elegans

Key words
germ cells, C. elegans, genetics, development, functional genomics

Program affiliation
Molecular Cell Biology
Neurosciences
Developmental Regenerative and Stem Cell Biology

Research summary
Interactions between the nervous system and the skeleton

Key words
bone, diabetes, nerve, neuropathy, neuroskeletal biology, obesity, metabolism, adipose tissue, adipocyte, high-resolution imaging, advanced quantification, RNAseq, regeneration, healing

Program affiliation
Immunology

Research summary
My research is focused on understanding the role of liver macrophages in metabolic liver disease and heart failure. Using pre-clinical models and human samples we seek to discover novel pathways to modulate immune function for patients with cardiometabolic disease and cardiogenic liver disease..

Key words
macrophages, tissue injury, infection, diabetes, heart failure, metabolic liver disease

Program affiliation
Neurosciences

Research summary
Our laboratory develops and validates blood and CSF biomarkers for Alzheimer disease and related disorders

Key words
biomarkers, Alzheimer disease, dementia, diagnostic tests, cognition

Program affiliation
Immunology

Research summary
My research interests are in the genetics of immune-mediated diseases and the fundamental mechanisms of immune cell activation, immune dysregulation, and immunological tolerance. My current work focuses on delineating the mechanisms underlying a monogenic syndrome of early-onset autoimmunity caused by gain-of-function (GOF) mutations in STAT3.

Key words
Immune dysregulation, inborn errors of immunity, Treg, STAT, Pediatric

Program affiliation
Immunology
Cancer Biology

Research summary
Cytokine receptor signaling and immunological protection against tumor development

Key words
cancer, lymphocyte, cytokine, signal transduction, tumor editing

Program affiliation
Developmental Regenerative and Stem Cell Biology
Immunology
Molecular Genetics and Genomics

Research summary
Regulation of hematopoietic stem cells (HSCs) by inflammation

Key words

Program affiliation
Molecular Cell Biology

Research summary
Receptor-mediated protein targeting and protein degradation

Key words
proteins, receptor, endocytosis, metabolism