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Erica Schmitt, MD, PhD

Assistant Professor

Program affiliation
Immunology

Research summary
My research interests are in the genetics of immune-mediated diseases and the fundamental mechanisms of immune cell activation, immune dysregulation, and immunological tolerance. My current work focuses on delineating the mechanisms underlying a monogenic syndrome of early-onset autoimmunity caused by gain-of-function (GOF) mutations in STAT3.

Key words
Immune dysregulation, inborn errors of immunity, Treg, STAT, Pediatric

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Robert Schreiber, PhD

Alumni Endowed Professor

Program affiliation
Immunology
Cancer Biology

Research summary
Cytokine receptor signaling and immunological protection against tumor development

Key words
cancer, lymphocyte, cytokine, signal transduction, tumor editing

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Laura Schuettpelz, MD, PhD

Professor

Program affiliation
Developmental Regenerative and Stem Cell Biology
Immunology
Molecular Genetics and Genomics

Research summary
Regulation of hematopoietic stem cells (HSCs) by inflammation

Key words

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Alan Schwartz, PhD, MD

Alumni Endowed Professor

Program affiliation
Molecular Cell Biology

Research summary
Receptor-mediated protein targeting and protein degradation

Key words
proteins, receptor, endocytosis, metabolism

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Drew Schwartz, MD, PhD

Assistant Professor

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Computational and Systems Biology
Molecular Genetics and Genomics

Research summary
Pediatric gut microbiome and immune disruption in serious bacterial infections

Key words
Microbiome, sepsis, bacteremia, infectious diseases, immune response, pediatrics

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Julie Schwarz, MD, PhD

Professor and Vice Chair of Research

Program affiliation
Cancer Biology
Molecular Cell Biology

Research summary
Studying cancer therapy resistance mechanisms in humans and preclinical models

Key words
Tumor metabolism, glycolysis, glutaminolysis, imaging, microenvironment, HPV, immunology, radiation therapy

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Rebecca Schwarzlose, PhD

Assistant Professor

Program affiliation
Neurosciences

Research summary
Neuroimaging studies of sensory processing and atypical sensory responding in children

Key words
functional MRI, development, anxiety, autism, sensory

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Clay Semenkovich, MD

Irene E. and Michael M. Karl Professor

Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Genetics and Genomics

Research summary
Molecular and cell biology of atherosclerosis and diabetes

Key words
aging, atherosclerosis, diabetes, lipids, obesity

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Ikbal Sencan-Egilmez, PhD

Assistant Professor

Program affiliation
Neurosciences

Research summary
Development and use of advanced optical microscopy solutions for preclinical imaging studies in brain and beyond

Key words
optical microscopy, neuroimaging, biomedical optics, oxygenation, neurovascular coupling, cerebral energetics

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Lori Setton, PhD

Professor & Chair

Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology

Research summary
Understanding the mechanisms for degeneration and regeneration of soft tissues of the musculoskeletal system, including the intervertebral disc, articular cartilage, and meniscus

Key words