Computational and Systems Biology

Program affiliation
Biomedical Informatics and Data Science
Computational and Systems Biology
Molecular Microbiology and Microbial Pathogenesis
Cancer Biology

Research summary
Novel genetic, microbial, and lifestyle risk factors for lung and gastrointestinal cancers leveraging large-scale clinical and population-based cohorts with deep genomic and phenotypic data

Key words
Systems and translational cancer epidemiology, microbiome, inflammation and immune-metabolic networks

Program affiliation
Neurosciences
Ecology and Evolutionary Biology
Computational and Systems Biology

Research summary
Sensory and Evolutionary Neuroscience

Key words
neural circuits, neurophysiology, sensory systems, behavior, evolution, mathematical modeling

Program affiliation
Neurosciences
Molecular Genetics and Genomics
Computational and Systems Biology

Research summary
Understanding the role of endogenous opioids in affective neuroscience and metabolic homeostasis

Key words
reward, valence, opioid, motivation, metabolism, diabetes

Program affiliation
Neurosciences
Computational and Systems Biology

Research summary
Exploring neuromorphic architectures using silicon and biological neurons; Novel self-powered neural recording systems

Key words

Program affiliation
Biomedical Informatics and Data Science
Computational and Systems Biology

Research summary
Health and economic burden of obesity and surgical treatments of obesity, transplant outcomes, multiple myeloma prevention and control, and health disparities.

Key words

Program affiliation
Computational and Systems Biology
Molecular Genetics and Genomics
Cancer Biology
Human and Statistical Genetics

Research summary
Liquid biopsy cancer detection

Key words

Program affiliation
Molecular Genetics and Genomics
Computational and Systems Biology

Research summary
Genomic analyses of regulatory networks, Non-coding disease variants

Key words
Genomics, Genetic Variation, High-Throughput Technologies, Single-Cell Regulatory Genomics, Computational Biology

Program affiliation
Molecular Genetics and Genomics
Neurosciences
Developmental Regenerative and Stem Cell Biology
Computational and Systems Biology

Research summary
(1) transcriptional networks in the retina; (2) the mechanistic basis of color vision; (3) the cis-regulatory basis of human uniqueness and neuropsychiatric disease

Key words
neurobiology, genomics, transcriptional networks, systems biology, photoreceptors, brain, neuropsychiatric disease, disease, cis-regulation

Program affiliation
Human and Statistical Genetics
Computational and Systems Biology
Molecular Genetics and Genomics

Research summary
Genetic variation in the variable response to pharmacologic treatment (i.e. Pharmacogenomics) of cardiovascular disease; specifically individuals with both diabetes mellitus and coronary artery disease.

Key words
cardiovascular disease, diabetes melitus, genotype, genetic variation

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Computational and Systems Biology
Molecular Genetics and Genomics
Ecology and Evolutionary Biology

Research summary
(1) Dynamics, ecology, and evolution of antibiotic resistance, (2) Engineering enhanced probiotics to treat GI disorders, (3) Engineering microbial biofuel catalysts

Key words
anibiotic resistance, synthetic biology, bioenergy, human microbiome, metagenomics, microbial ecology and biodiversity