Computational and Systems Biology

Program affiliation
Computational and Systems Biology
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology

Research summary
Systems and synthetic cell biology: quantitative analysis of cellular organization

Key words

Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Computational and Systems Biology

Research summary
Understanding how mitochondria are built, regulated, and maintained

Key words
mitochondria, phosphorylation, metabolism, signaling, kinase, phosphatase

Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Computational and Systems Biology
Immunology

Research summary

Key words

Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology
Computational and Systems Biology

Research summary
My research program aims to understand the neural circuits that underlie vocal communication processing and investigate how these circuits are disrupted in neuropsychiatric disorders.

Key words
Auditory System, Neuropsychiatric Disorders, Mouse Models, Communication Processing, Development

Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Computational and Systems Biology

Research summary
We seek to understand the cellular and biochemical underpinnings of mitochondrial dysfunction in human diseases. Our work integrates large-scale methodologies with traditional biochemistry and cell biology to investigate the modulation, adaptation, and basic metabolic function of mitochondria.

Key words
Mitochondria, Protein biochemistry, Genetic screening, Metabolism, Biosynthesis, Orphan protein function, Proteomics, Metabolomics, Kinases and phosphates, Metabolic disease, Systems biochemistry

Program affiliation
Immunology
Computational and Systems Biology
Neurosciences

Research summary
Mechanisms of inflammation in immune-privileged organs

Key words

Program affiliation
Biochemistry Biophysics and Structural Biology
Computational and Systems Biology
Plant and Microbial Biosciences

Research summary
Biophysics of intrinsically disordered proteins

Key words
Huntington`s disease; Polyglutamine Aggregation; Intrinsically Disordered Proteins; Phase transitions in cell biology; Self-assembly; Transcriptional regulation; Small-scale Systems Biology & Interaction Networks;

Program affiliation
Neurosciences
Cancer Biology
Computational and Systems Biology

Research summary
Our lab employs cutting-edge molecular biology techniques to investigate the genetic, epigenetic, and cellular alterations driving the initiation, progression, and therapeutic resistance of brain tumors.

Key words
brain tumors, systems biology, genetics, neurosurgery, neurooncology

Program affiliation
Cancer Biology
Computational and Systems Biology
Biochemistry Biophysics and Structural Biology
Biomedical Informatics and Data Science

Research summary
To understand the metabolic crosstalk between cells and tissues in disease models such as cancer by using isotopes and metabolomics

Key words
metabolism, metabolomics, mass spectrometry, bioinformatics, imaging, cancer, tumor microenvironment, isotope tracing

Program affiliation
Biomedical Informatics and Data Science
Computational and Systems Biology
Biochemistry Biophysics and Structural Biology

Research summary
Translational Bioinformatics, Clinical Research Informatics

Key words
Biomedical Informatics, Data Science, Data Analytics, Clinical Research, Translational Research