Computational and Systems Biology
Ben Major, PhD
Alan A. and Edith L. Wolff Professor
- Email: bmajor@wustl.edu
Program affiliation
Cancer Biology
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Computational and Systems Biology
Research summary
Studying how perturbation of specific signal transduction pathways contributes to the initiation, progression and dissemination of cancer
Key words
proteomics, functional genomics, lung cancer, signal transduction, WNT, oxidative stress
Ben Mansfeld, PhD
Assistant Professor
- Email: bmansfeld@wustl.edu
Program affiliation
Plant and Microbial Biosciences
Computational and Systems Biology
Biomedical Informatics and Data Science
Research summary
The Mansfeld Lab uses various non‑model species and a hypothesis driven, systems approach to examine how circadian rhythm, development, and tissue type impact plant defense.
Key words
Plant Pathology, Genomics, Bioinformatics, Disease Resistance
Dimitrious Mathios, MD
Assistant Professor
- Email: mathios@wustl.edu
Program affiliation
Computational and Systems Biology
Molecular Genetics and Genomics
Biomedical Informatics and Data Science
Research summary
Development of liquid biopsy approaches for brain tumors
Key words
liquid biopsy, cfDNA, genetics, epigenetics
Michael Meers, PhD
Assistant Professor
- Email: meers@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Computational and Systems Biology
Cancer Biology
Developmental Regenerative and Stem Cell Biology
Research summary
Understanding the molecular determinants of cellular diversity
Key words
Chromatin, Transcription Factors, Epigenomics, Cell fate, Single-cell
Robi Mitra, PhD
Alvin Goldfarb Professor of Computational Biology
- Email: rmitra@wustl.edu
Program affiliation
Computational and Systems Biology
Molecular Genetics and Genomics
Research summary
Technology development for functional genomics and systems biology
Key words
functional genomics, systems biology, technology development, bioinformatics
Makedonka Mitreva, PhD
Professor
- Email: mmitreva@wustl.edu
Program affiliation
Computational and Systems Biology
Molecular Genetics and Genomics
Molecular Microbiology and Microbial Pathogenesis
Biochemistry Biophysics and Structural Biology
Research summary
Next-generation experimental, multi-omic and computational approaches to empower the study of infectious diseases and the human microbiome
Key words
Genomics of Infectious Diseases, Helminth Genomics, Human Metagenomics
Brian Muegge, MD, PhD
Assistant Professor
- Email: mueggeb@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Computational and Systems Biology
Molecular Cell Biology
Research summary
Targeting Enteroendocrine Cell Development to Treat Metabolic Diseases
Key words
Genomics, Single-Cell, Endocrinology, Stem Cells, Gastroenterology, Intestine, Epigenetics
Shankar Mukherji, PhD
Associate Professor
- Email: smukherji@wustl.edu
Program affiliation
Computational and Systems Biology
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
Systems and synthetic cell biology: quantitative analysis of cellular organization
Key words
Natalie M. Niemi, PhD
Assistant Professor
- Email: niemi@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Computational and Systems Biology
Research summary
Understanding how mitochondria are built, regulated, and maintained
Key words
mitochondria, phosphorylation, metabolism, signaling, kinase, phosphatase
Miranda Orr, PhD
Associate Professor
- Email: orr.m@wustl.edu
Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Computational and Systems Biology
Immunology
Research summary
Key words