Computational and Systems Biology

Program affiliation
Immunology
Computational and Systems Biology
Molecular Microbiology and Microbial Pathogenesis

Research summary
Investigating the development of immunological memory in disease states

Key words
B cells, immunological memory, germinal center, virus, allergy

Program affiliation
Computational and Systems Biology
Molecular Genetics and Genomics

Research summary
Modeling the evolution of species with stochastic processes [Recruiting PhD Students for Fall 2024]

Key words
phylogenetics, evolution, ecology, epidemiology, statistical models, stochastic processes, computational inference, deep learning

Program affiliation
Neurosciences
Computational and Systems Biology

Research summary

Key words

Program affiliation
Computational and Systems Biology
Molecular Genetics and Genomics
Human and Statistical Genetics

Research summary
Integration of whole-genome sequence with phenotypic data to understand parent-of-origin genetic effects and gene-by-environment interactions

Key words
Epigenetics, gene regulation, parent-of-origin effects, gene-by-environment interactions, pleiotropy, systems biology, metabolism, evolution

Program affiliation
Neurosciences
Computational and Systems Biology

Research summary
Pathogenesis of amyloid fibrils and amyloid plaques in AD mouse models

Key words
brain ischemia, stroke recovery, Alzheimer’s disease, amyloid

Program affiliation
Biomedical Informatics and Data Science
Computational and Systems Biology
Cancer Biology

Research summary
Integrative large-scale pharmaco genomics analysis for target, signaling network, drug and drug combination discovery. Genomics data driven tumor-stromal communication discovery and modeling.

Key words

Program affiliation
Computational and Systems Biology
Biochemistry Biophysics and Structural Biology
Biomedical Informatics and Data Science

Research summary
Control and optimization of large-scale complex systems with applications ranging from quantum mechanics and neuroscience to bioinformatics

Key words
computational mathematics, control theory, optimization, dynamical systems, MRI, NMR, neuroscience

Program affiliation
Computational and Systems Biology
Biomedical Informatics and Data Science
Molecular Genetics and Genomics
Cancer Biology
Neurosciences

Research summary
Our research interests include developing innovative computational tools/methods and utilizing single-cell (epi)genomic techniques to gain a comprehensive understanding of gene regulation in mammalian models and human diseases, particularly in brain tumors and neuropsychiatric disorders.

Key words
Bioinformatics, Gene Regulation, Single-cell Epigenetics, Brain Tumors, Neurological Disorders

Program affiliation
Computational and Systems Biology
Molecular Microbiology and Microbial Pathogenesis
Plant and Microbial Biosciences

Research summary
A computational and experimental lab studying bacterial colonization and transmission at the boundary of built and natural environments and exploring microbiomes as environmental sensors and public health sentinels

Key words

Program affiliation
Cancer Biology
Computational and Systems Biology
Molecular Genetics and Genomics
Human and Statistical Genetics

Research summary
Translational Cancer Genomics; Noncoding RNAs

Key words
non-coding RNAs, lncRNAs, cancer genomics, transcriptome, bioinformatics, computational biology, solid tumor malignancies