Molecular Cell Biology
Jeffrey Bednarski II, MD, PhD
Associate Professor
- Email: bednarski_j@wustl.edu
Program affiliation
Immunology
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
Understanding the signals that direct early hematopoiesis and B cell lymphopoiesis
Key words
Carmen Bergom, MD, PhD
Associate Professor
- Email: cbergom@wustl.edu
Program affiliation
Cancer Biology
Molecular Genetics and Genomics
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Research summary
Identification of new targets to improve tumor radiation effectiveness and to protect normal tissues such as the heart from radiation injury
Key words
Carlos Bernal-Mizrachi, MD
Philip E. and Carolyn E. Cryer Professor
- Email: cbernal@wustl.edu
Program affiliation
Molecular Cell Biology
Research summary
Novel mechanisms of cardiovascular disease in human and mouse models with insulin resistance and type 2 DM
Key words
Kendall Blumer, PhD
Professor
- Email: kblumer@wustl.edu
Program affiliation
Molecular Cell Biology
Cancer Biology
Biochemistry Biophysics and Structural Biology
Research summary
Tumor cell biology, signal transduction, and drug development
Key words
cancer, signal transduction, molecular pharmacology, autophagy, metabolism, drug development
Ron Bose, MD, PhD
Associate Professor
- Email: rbose@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
Genomics and Cell Signaling in Breast Cancer
Key words
cancer, genomics, organoids, 3D culture, receptor tyrosine kinase, signal transduction, next-generation sequencing, targeted therapy of cancer
Jonathan Brestoff, MD, PhD, MPH
Associate Professor
- Email: brestoff@wustl.edu
Program affiliation
Immunology
Molecular Cell Biology
Neurosciences
Research summary
Understanding how immune cells and metabolic organs interact to maintain normal metabolism and to support adaptation to physiologic challenges
Key words
Immunometabolism, Mitochondria, White/beige/brown adipose tissue, Innate immunity, Macrophages, Obesity
Steven Brody, MD
Professor
- Email: brodys@wustl.edu
Program affiliation
Molecular Cell Biology
Research summary
Molecular and genetic mechanisms of airway epithelial cell differentiation and ciliogenesis
Key words
cilia, development, epithelium, lung, transcription
Rita Brookheart, PhD
Assistant Professor
- Email: rbrookheart@wustl.edu
Program affiliation
Molecular Cell Biology
Research summary
We focus on the intersection of metabolism and stress responses in human health and disease. We use basic and translational approaches to identify and investigate key metabolic regulators in both physiologic and pathophysiologic contexts including obesity and diabetes.
Key words
Metabolism, skeletal muscle, ER stress, calcium, mitochondria, SREBP, obesity, diabetes