Molecular Cell Biology
Carlos Bernal-Mizrachi, MD
Philip E. and Carolyn E. Cryer Professor
- Email: cbernal@wustl.edu
Program affiliation
Molecular Cell Biology
Research summary
Novel mechanisms of cardiovascular disease in human and mouse models with insulin resistance and type 2 DM
Key words
Kendall Blumer, PhD
Professor
- Email: kblumer@wustl.edu
Program affiliation
Molecular Cell Biology
Cancer Biology
Biochemistry Biophysics and Structural Biology
Research summary
Tumor cell biology, signal transduction, and drug development
Key words
cancer, signal transduction, molecular pharmacology, autophagy, metabolism, drug development
Ron Bose, MD, PhD
Associate Professor
- Email: rbose@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
Genomics and Cell Signaling in Breast Cancer
Key words
cancer, genomics, organoids, 3D culture, receptor tyrosine kinase, signal transduction, next-generation sequencing, targeted therapy of cancer
Jonathan Brestoff, MD, PhD, MPH
Associate Professor
- Email: brestoff@wustl.edu
Program affiliation
Immunology
Molecular Cell Biology
Neurosciences
Research summary
Understanding how immune cells and metabolic organs interact to maintain normal metabolism and to support adaptation to physiologic challenges
Key words
Immunometabolism, Mitochondria, White/beige/brown adipose tissue, Innate immunity, Macrophages, Obesity
Steven Brody, MD
Professor
- Email: brodys@wustl.edu
Program affiliation
Molecular Cell Biology
Research summary
Molecular and genetic mechanisms of airway epithelial cell differentiation and ciliogenesis
Key words
cilia, development, epithelium, lung, transcription
Jeffrey Brown, MD PhD
Assistant Professor
- Email: brownjw@wustl.edu
Program affiliation
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Developmental Regenerative and Stem Cell Biology
Research summary
Key words
Peter Burgers, PhD
Professor
- Email: burgers@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Genetics and Genomics
Molecular Cell Biology
Research summary
Molecular Biology of DNA replication and damage response in yeast and human
Key words
Cell cycle, DNA damage response, DNA replication, Checkpoints, Mutagenesis, DNA repair, yeast
Siyan Cao, MD, PhD
Assistant Professor
- Email: caos@wustl.edu
Program affiliation
Immunology
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Biomedical Informatics and Data Science
Research summary
We study disease-relevant cell and organ signaling pathways in inflammatory bowel disease using molecular and cell biology, multi-omics technologies, genetic murine models, and patient samples.
Key words
inflammatory bowel disease, mucosal immunity, innate lymphoid cells, human intestinal organoids, regenerative medicine, biomarker discovery, cellular stress response, perianal fistulizing Crohn's disease, eosinophilic esophagitis, colon cancer