Molecular Cell Biology
Valeria Cavalli, PhD
Robert E. and Louise F. Dunn Professor of Biomedical Research
- Email: cavalli@wustl.edu
Program affiliation
Neurosciences
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
Cellular, Molecular and Epigenetic control of axon regeneration
Key words
axon regeneration, nerve injury, epigenetic, transcription, glia biology, neuroimmune mechanisms, spinal cord injury, optic nerve injury
Grant Challen, PhD
Professor
- Email: grantchallen@wustl.edu
Program affiliation
Cancer Biology
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
Understanding the genetic and epigenetic mechanisms that regulate normal and leukemic stem cells
Key words
Hematopoietic stem cells, Leukemia stem cells, Epigenetic modifications
Alexander Chamessian, MD PhD
Assistant Professor
- Email: a.chamessian@wustl.edu
Program affiliation
Neurosciences
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Computational and Systems Biology
Research summary
Key words
Baron Chanda, PhD
Professor
- Email: bchanda@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Neurosciences
Molecular Cell Biology
Research summary
Mechanisms and Design Principles of Ion Channel Function and Gating
Key words
Tao Che, PhD
Associate Professor
- Email: taoche@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Neurosciences
Research summary
Characterizing and dissecting the molecular mechanisms of opioid receptor signaling
Key words
GPCRs, Analgesics, Side effects, opioid receptors, opioids, opioid alternatives
Chun-Kan Chen, PhD
Assistant Professor
- Email: chun-kan@wustl.edu
Program affiliation
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Molecular Genetics and Genomics
Research summary
The Chen lab utilizes multi-omic and high-throughput screening approaches to investigate the regulation and function of circRNA and uncover the molecular mechanisms of circRNA-mediated disease.
Key words
Circular RNA, Oxidative Stress, RNA Translation, Cancer Vaccine
Haobin Chen, MD, PhD
Assistant Professor
- Email: c.haobin@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
Identifying new therapeutic targets of small cell lung cancer
Key words
Lung cancer, DNA damage repair, immunology, drug resistance, genetic screening, translational research, drug development, targeted therapy, precision therapy
Yao Chen, PhD
Assistant Professor
- Email: yaochen@wustl.edu
Program affiliation
Neurosciences
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Molecular Genetics and Genomics
Computational and Systems Biology
Research summary
Understanding the function of neuromodulators and sleep through the spatiotemporal dynamics of molecular signals
Key words
neuromodulator, sleep, dynamics, sensors, actuators, signaling, G protein coupled receptors, imaging, microscopy, learning, plasticity, engineering
Ying Chen, MD, PhD
Assistant Professor
- Email: ychen32@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Research summary
Understanding the molecular mechanisms of primary nephrotic syndrome (NS)
Key words
Wayland Cheng, MD, PhD
Assistant Professor
- Email: wayland.cheng@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Neurosciences
Molecular Cell Biology
Research summary
I am interested in the structure and function of neuronal ligand-gated ion channels, and the mechanism of channel modulation by endogenous lipids or exogenous drugs such as general anesthetics.
Key words