Molecular Cell Biology
Paul Bridgman, PhD
Professor
- Email: bridgmap@wustl.edu
Program affiliation
Neurosciences
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Research summary
Cell biology of developing nerve and muscle cells
Key words
neurobiology, development, imaging, axon, cytoskeleton
Steven Brody, MD
Professor
- Email: brodys@wustl.edu
Program affiliation
Molecular Cell Biology
Research summary
Molecular and genetic mechanisms of airway epithelial cell differentiation and ciliogenesis
Key words
cilia, development, epithelium, lung, transcription
Rita Brookheart, PhD
Assistant Professor
- Email: rbrookheart@wustl.edu
Program affiliation
Molecular Cell Biology
Research summary
We focus on the intersection of metabolism and stress responses in human health and disease. We use basic and translational approaches to identify and investigate key metabolic regulators in both physiologic and pathophysiologic contexts including obesity and diabetes.
Key words
Metabolism, skeletal muscle, ER stress, calcium, mitochondria, SREBP, obesity, diabetes
Peter Burgers, PhD
Professor
- Email: burgers@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Genetics and Genomics
Molecular Cell Biology
Research summary
Molecular Biology of DNA replication and damage response in yeast and human
Key words
Cell cycle, DNA damage response, DNA replication, Checkpoints, Mutagenesis, DNA repair, yeast
Valeria Cavalli, PhD
Robert E. and Louise F. Dunn Professor of Biomedical Research
- Email: cavalli@wustl.edu
Program affiliation
Neurosciences
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
Cellular, Molecular and Epigenetic control of axon regeneration
Key words
axon regeneration, nerve injury, epigenetic, transcription, glia biology, neuroimmune mechanisms, spinal cord injury, optic nerve injury
Grant Challen, PhD
Assistant Professor
- Email: grantchallen@wustl.edu
Program affiliation
Cancer Biology
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
Understanding the genetic and epigenetic mechanisms that regulate normal and leukemic stem cells
Key words
Hematopoietic stem cells, Leukemia stem cells, Epigenetic modifications
Baron Chanda, PhD
Professor
- Email: bchanda@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Neurosciences
Molecular Cell Biology
Research summary
Mechanisms and Design Principles of Ion Channel Function and Gating
Key words
Tao Che, PhD
Assistant Professor
- Email: taoche@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Neurosciences
Research summary
Characterizing and dissecting the molecular mechanisms of opioid receptor signaling
Key words
GPCRs, Analgesics, Side effects, opioid receptors, opioids, opioid alternatives
Chun-Kan Chen, PhD
Assistant Professor
- Email: chun-kan@wustl.edu
Program affiliation
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Molecular Genetics and Genomics
Research summary
The Chen lab utilizes multi-omic and high-throughput screening approaches to investigate the regulation and function of circRNA and uncover the molecular mechanisms of circRNA-mediated disease.
Key words
Circular RNA, Hypoxia Stress, Single Cell Multiomics, Proteomics
Haobin Chen, MD, PhD
Assistant Professor
- Email: c.haobin@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
Identifying new therapeutic targets of small cell lung cancer
Key words
Lung cancer, DNA damage repair, immunology, drug resistance, genetic screening, translational research, drug development, targeted therapy, precision therapy