Molecular Genetics and Genomics

Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics

Research summary
Understanding how glia shape developmental and pathological plasticity

Key words
astrocytes, plasticity, circuits, development, myelination

Program affiliation
Molecular Genetics and Genomics
Biomedical Informatics and Data Science

Research summary
Utilizing the power of genetics to elucidate the molecular pathogenesis of disease and transform patient care

Key words
Genetics, genomics, transcription factors, rare disease

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Molecular Genetics and Genomics
Immunology
Computational and Systems Biology

Research summary
Defining the mechanisms behind and effects of the interactions between commensal bacteria, pathogens and innate immunity

Key words
microbiota, infection, pathogen, microbiome, virus, interferon, immunity

Program affiliation
Molecular Cell Biology
Molecular Genetics and Genomics
Biochemistry Biophysics and Structural Biology

Research summary
Signal transduction by G proteins and pathogenesis of diabetes

Key words
diabetes, Drosophila, G protein, hormones, protein structure, signal transduction

Program affiliation
Biochemistry Biophysics and Structural Biology
Plant and Microbial Biosciences
Molecular Genetics and Genomics

Research summary
Possible cure for MS: intravenous access by myelin-binding aptamer; PCR at one temp; RT-enabled Taq pol.

Key words
DNA, aptamers, technology development, brain therapy

Program affiliation
Molecular Cell Biology
Cancer Biology
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics

Research summary
Understanding the role of DNA damage and RNA degradation during tissue homeostasis, regeneration, aging, and cancer

Key words
DNA damage; DNA repair; Telomerase; Stem cell biology; Cancer; Aging

Program affiliation
Immunology
Molecular Cell Biology
Molecular Genetics and Genomics

Research summary
Understanding the signals that direct early B cell development

Key words

Program affiliation
Biomedical Informatics and Data Science
Molecular Genetics and Genomics
Computational and Systems Biology
Neurosciences

Research summary
Our research is dedicated to understanding the genetics of Alzheimer’s disease and related disorders, employing bioinformatic tools and a big-data approach that integrates genetics, multi-omics, brain imaging, and clinical data.

Key words
Genetics, Multi-Omics, Bioinformatics, Neurodegeneration, Alzheimer's disease

Program affiliation
Neurosciences
Molecular Genetics and Genomics
Ecology and Evolutionary Biology
Biomedical Informatics and Data Science

Research summary
Molecular, cellular, genetic and evolutionary mechanisms of behavior

Key words
Behavioral genetics, Evolutionary neurogenetics, Drosophila, Ion channels, Molecular genetics, Neurobiology, Neuroethology, Sensory systems

Program affiliation
Cancer Biology
Molecular Genetics and Genomics
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology

Research summary
Identification of new targets to improve tumor radiation effectiveness and to protect normal tissues such as the heart from radiation injury

Key words