Molecular Genetics and Genomics
Stephen Kerry Kornfeld, MD, PhD
Professor
- Email: kornfeld@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
organismal aging; zinc homeostasis and roles of zinc during cell differentiation.
Key words
aging, metals, zinc, development, sperm activation, signal transduction, homeostasis
John Krais, PhD
Assistant Professor
- Email: krais@wustl.edu
Program affiliation
Cancer Biology
Molecular Genetics and Genomics
Molecular Cell Biology
Research summary
Our laboratory focuses on the fundamental issues of DNA repair and how they relate to cancer initiation, progression, and therapy responses.
Key words
DNA repair, DNA replication
Barbara Kunkel, PhD
Professor
- Email: kunkel@wustl.edu
Program affiliation
Plant and Microbial Biosciences
Molecular Microbiology and Microbial Pathogenesis
Molecular Genetics and Genomics
Research summary
Molecular genetic analysis of disease development in Pseudomonas syringae-Arabidopsis interactions
Key words
plant-microbe interactions, bacterial pathogenesis, auxin, IAA, Type III effector protein, genetics, plant biology
Michael Landis, PhD
Associate Professor
- Email: michael.landis@wustl.edu
Program affiliation
Computational and Systems Biology
Molecular Genetics and Genomics
Research summary
Modeling the evolution of species with stochastic processes [Recruiting PhD Students for Fall 2024]
Key words
phylogenetics, evolution, ecology, epidemiology, statistical models, stochastic processes, computational inference, deep learning
Heather Lawson, PhD
Assistant Professor
- Email: lawson@wustl.edu
Program affiliation
Computational and Systems Biology
Molecular Genetics and Genomics
Human and Statistical Genetics
Research summary
Integration of whole-genome sequence with phenotypic data to understand parent-of-origin genetic effects and gene-by-environment interactions
Key words
Epigenetics, gene regulation, parent-of-origin effects, gene-by-environment interactions, pleiotropy, systems biology, metabolism, evolution
Timothy Ley, MD
Lewis T. and Rosalind B. Apple Chair in Oncology
- Email: timley@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Immunology
Cancer Biology
Research summary
Study of normal versus leukemic blood cell development and immunology
Key words
cancer genomics, leukemia, oncogene
Qingyun Li, PhD
Assistant Professor
- Email: qingyunli@wustl.edu
Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Research summary
Microglial biology and neuro-immune interactions in development, aging and disease
Key words
microglia, neuroimmunology, development, aging, neurodegeneration, single cell
Yang Li, PhD
Assistant Professor
- Email: yeli@wustl.edu
Program affiliation
Computational and Systems Biology
Biomedical Informatics and Data Science
Molecular Genetics and Genomics
Cancer Biology
Neurosciences
Research summary
Our research interests include developing innovative computational tools/methods and utilizing single-cell (epi)genomic techniques to gain a comprehensive understanding of gene regulation in mammalian models and human diseases, particularly in brain tumors and neuropsychiatric disorders.
Key words
Bioinformatics, Gene Regulation, Single-cell Epigenetics, Brain Tumors, Neurological Disorders
Susan Lin, MD
Assistant Professor
- Email: susanlin@wustl.edu
Program affiliation
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Research summary
Key words
Daniel Link, MD
Alan and Edith Wolff Professor of Medicine
- Email: dlink@wustl.edu
Program affiliation
Cancer Biology
Immunology
Molecular Genetics and Genomics
Molecular Cell Biology
Research summary
Regulation of normal and malignant hematopoiesis
Key words
Leukemia, clonal hematopoiesis, stem cells, niche, ribosome, cancer metabolism, neutrophils, genomics