Molecular Genetics and Genomics
Albert H. Kim, MD, PhD
August A. Busch, Jr. Professor
- Email: alberthkim@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Computational and Systems Biology
Neurosciences
Cancer Biology
Research summary
Genetic and epigenetic changes that drive malignant behavior in brain tumors
Key words
brain tumors, glioblastoma, meningioma, neural stem cells
Jonathan Kipnis, PhD
BJC Investigator & Alan A. and Edith L. Wolff Distinguished Professor
- Email: kipnis@wustl.edu
Program affiliation
Immunology
Neurosciences
Molecular Genetics and Genomics
Molecular Cell Biology
Research summary
We study complex interactions between the immune and nervous systems in health and disease
Key words
Neuroimmunology; neuroscience; immunology; lymphatics; behavior; Alzheimer’s disease; neurodegeneration; glia; microglia; blood-brain barrier (BBB); meninges
Alexander Knights, PhD
Assistant Professor
- Email: aknights@wustl.edu
Program affiliation
Immunology
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
We are fundamentally interested in the complex cellular and molecular interactions that take place during joint homeostasis and disease.
Key words
Osteoarthritis, Immunology, Crosstalk, Fibrosis, Inflammation
Kerry Kornfeld, MD, PhD
Professor
- Email: kornfeld@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
organismal aging; zinc homeostasis and roles of zinc during cell differentiation.
Key words
aging, metals, zinc, development, sperm activation, signal transduction, homeostasis
John Krais, PhD
Assistant Professor
- Email: krais@wustl.edu
Program affiliation
Cancer Biology
Molecular Genetics and Genomics
Molecular Cell Biology
Research summary
Our laboratory focuses on the fundamental issues of DNA repair and how they relate to cancer initiation, progression, and therapy responses.
Key words
DNA repair, DNA replication, cancer development, targeted therapy, therapy resistance
Barbara N. Kunkel, PhD
Professor
- Email: kunkel@wustl.edu
Program affiliation
Plant and Microbial Biosciences
Molecular Microbiology and Microbial Pathogenesis
Molecular Genetics and Genomics
Research summary
Molecular genetic analysis of disease development in Pseudomonas syringae-Arabidopsis interactions
Key words
plant-microbe interactions, bacterial pathogenesis, auxin, IAA, Type III effector protein, genetics, plant biology
Michael J. Landis, PhD
Associate Professor
- Email: michael.landis@wustl.edu
Program affiliation
Computational and Systems Biology
Molecular Genetics and Genomics
Research summary
Modeling the evolution of species with stochastic processes [Recruiting PhD Students for Fall 2024]
Key words
phylogenetics, evolution, ecology, epidemiology, statistical models, stochastic processes, computational inference, deep learning
Heather A. Lawson, PhD
Assistant Professor
- Email: lawson@wustl.edu
Program affiliation
Computational and Systems Biology
Molecular Genetics and Genomics
Human and Statistical Genetics
Research summary
Integration of whole-genome sequence with phenotypic data to understand parent-of-origin genetic effects and gene-by-environment interactions
Key words
Epigenetics, gene regulation, parent-of-origin effects, gene-by-environment interactions, pleiotropy, systems biology, metabolism, evolution
Timothy J. Ley, MD
Lewis T. and Rosalind B. Apple Chair in Oncology
- Email: timley@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Immunology
Cancer Biology
Research summary
Study of normal versus leukemic blood cell development and immunology
Key words
cancer genomics, leukemia, oncogene
Tristan Li, PhD
Assistant Professor
- Email: qingyunli@wustl.edu
Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Research summary
Microglial biology and neuro-immune interactions in development, aging and disease
Key words
microglia, neuroimmunology, development, aging, neurodegeneration, single cell