Molecular Genetics and Genomics
Angela Hirbe, MD, PhD
Associate Professor
- Email: hirbea@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
Utilization of genomic information from sarcomas to better understand the pathogenesis of these tumors and to identify biomarkers and therapeutic targets for these aggressive cancers.
Key words
sarcoma, metastasis, genomics, cell signalling, NF1, MPNST
Ashley Housten, OTD, OTR/L, MSCI, MPA
Associate Professor
- Email: ahousten@wustl.edu
Program affiliation
Biomedical Informatics and Data Science
Molecular Genetics and Genomics
Research summary
Key words
shared decision making, health equity, implementation science
Eric Huang, MD, PhD
Joseph M. Davie Distinguished Professor and Chair of the Department of Pathology and Immunology
- Email: erichuang@wustl.edu
Program affiliation
Immunology
Neurosciences
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Research summary
Key words
Laura Ibanez, PhD
Assistant Professor
- Email: ibanezl@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Research summary
Our lab is focused on developing new, minimally invasive tools for rapid and accurate diagnosis of neurodegenerative diseases during the pre-symptomatic phases and predicting of outcomes during the acute phase of ischemic strokes.
Key words
Shin-ichiro Imai, MD, PhD
Professor
- Email: imaishin@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Neurosciences
Molecular Genetics and Genomics
Molecular Cell Biology
Research summary
Understanding the molecular mechanism of aging and longevity in mammals
Key words
aging, longevity, hypothalamus, metabolism, NAD biosynthesis, Sirt1, NAMPT, NAD World
Sanjay Jain, MD, PhD
Associate Professor
- Email: sjain22@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Biomedical Informatics and Data Science
Research summary
Interactions between the nervous and genitourinary systems during development, molecular basis for heterogeneity in progenitors and their lineage commitments in the GU tract, injury and regeneration using animal models, mechanisms of malformations using organoids from iPSCs
Key words
cell fate, gene expression, genomics, disease models, growth factor signaling, kidney, bladder, innervation, stem cells, organogenesis, nervous system development, birth defects
Aimee James, PhD, MPH
Associate Professor
- Email: aimeejames@wustl.edu
Program affiliation
Human and Statistical Genetics
Molecular Genetics and Genomics
Research summary
Cancer prevention and control, health disparities and community-based research
Key words
Joanna Jankowsky, PhD
Professor
- Email: jankowsky@wustl.edu
Program affiliation
Neurosciences
Molecular Genetics and Genomics
Molecular Cell Biology
Research summary
Cellular and molecular pathogenesis of Alzheimer's disease
Key words
Alzheimer's disease, neurodegeneration, amyloid, tau, mouse models, risk factors, lysosome, gene therapy
Ali Javaheri, MD, PhD
Assistant Professor
- Email: ali.javaheri@wustl.edu
Program affiliation
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
Key words
Peter Jin
Assistant Professor
- Email: jin810@wustl.edu
Program affiliation
Computational and Systems Biology
Molecular Genetics and Genomics
Biomedical Informatics and Data Science
Human and Statistical Genetics
Research summary
We use human genetic, functional genomic, and bioinformatic approaches to understand the consequence of genetic variants underlying diseases
Key words
Functional genomics, bioinformatics, human genetics, data science, rare diseases, structural variation