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Yousef Abu-Amer, Ph.D.
- Investigating molecular mechanisms underlying inflammation-induced degenerative skeletal diseases including joint degeneration, inflammatory arthritis and osteolysis
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Jennifer Alexander-Brett, M.D., Ph.D.
- Respiratory immunobiology, with particular interest in cytokine pathways associated with lung epithelial progenitors
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Rajendra S. Apte, M.D., Ph.D.
- Innate immunity and immune effector mechanisms in the retina; oxidative stress and cell death; models of developmental angiogenesis and neovascularization; inflammation and photoreceptor survival; macular degeneration
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Jeffrey M. Arbeit, M.D.
- Molecular regulation of epithelial carcinogenesis
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Vivek K. Arora, M.D., Ph.D.
- I am physician-scientist with complementary clinical and research interests focused on genitourinary cancer
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Steven Bassnett, Ph.D.
- Cell and molecular biology of the ocular lens
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Luis F.Z. Batista, Ph.D.
- Understanding the importance of telomerase in human stem and progenitor cell function and regulation
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Irving Boime, Ph.D.
- Placental and pituitary hormone genes
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Azad Bonni, M.D., Ph.D.
- Regulation of neuronal connectivity in brain development and disease
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Paul C. Bridgman, Ph.D.
- Cell biology of developing nerve and muscle cells
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Andreas H. Burkhalter, Ph.D.
- Structure and physiology of neuronal circuits in mouse visual cortex
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Valeria Cavalli, Ph.D.
- Cellular, Molecular and Epigenetic control of axon regeneration
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Douglas L. Chalker, Ph.D.
- Genetic and epigenetic regulation of developmentally programmed DNA rearrangements of Tetrahymena
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Grant Challen, Ph.D.
- Understanding the genetic and epigenetic mechanisms that regulate normal and leukemic stem cells
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Feng Chen, Ph.D.
- Molecular genetic studies of urogenital diseases
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Shiming Chen, Ph.D.
- Molecular mechanisms regulating photoreceptor gene expression in healthy and diseased retinas
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Zhou-Feng Chen, Ph.D.
- Molecular and cellular mechanisms of itch sensation
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Milan G. Chheda, M.D.
- Understanding epigenetic and genetic mechanisms governing the cancer stem cell state
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Kyunghee Choi, Ph.D.
- Hematopoietic, Vascular and Cardiac Development in Mammalian System
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Richard A. Chole, M.D., Ph.D.
- Role of Pseudomonas aeruginosa biofilms in cholesteatoma
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F. Sessions Cole, M.D.
- Genetic lung disease, Surfactant protein B, and rare diseases in infants
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Joseph C. Corbo, M.D., Ph.D.
- (1) transcriptional networks in the retina; (2) the mechanistic basis of color vision; (3) the cis-regulatory basis of human uniqueness and neuropsychiatric disease
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Erika C. Crouch, Ph.D., M.D.
- Structure and function of surfactant protein D (SP-D)
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Aaron DiAntonio, M.D., Ph.D.
- Neural circuits in development and disease
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Li Ding, Ph.D.
- Cancer genomics and proteomics
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Todd Druley, M.D., Ph.D.
- Genomic technology development to enable characterize the role of rare genetic variants in complex disease, particularly pediatric cancer.
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Ian W. Duncan, Ph.D.
- Temporal control of target gene specificity for developmental regulators in Drosophila
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Takeshi Egawa, M.D., Ph.D.
- Gene regulation for lymphocyte development and adaptive immune responses
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Guy M. Genin, Ph.D.
- Interfaces and adhesions in physiology and nature
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Yehuda Ginosar, M.D.
- Identify interventions that may improve uteroplacental perfusion in chronic fetal asphyxia and to enhance intrauterine fetal growth and development
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Matthew I. Goldsmith, M.D.
- Skeletal growth and regeneration in zebrafish
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Misty Good, M.D., M.S.
- Focus on the cellular and molecular mechanisms involved in the development of necrotizing enterocolitis (NEC), a disease affecting the intestine of premature babies
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Michael J. Greenberg, Ph.D.
- Cytoskeletal molecular motors in health and disease. We are currently studying the effects of mutations that cause heart disease.
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Charles A. Harris, M.D., Ph.D.
- We aim to understand the molecular mechanisms underlying metabolic effects of glucocorticoids.
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Erik D. Herzog, Ph.D.
- Cellular and molecular analysis of circadian rhythms in mammals
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Didier Hodzic, Ph.D.
- Role of LINC complexes (Linkers of the Nucleoskeleton to the Cytoskeleton) in nucleokinesis and neuronal migration
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James J. Hsieh, M.D., Ph.D.
- Integrate contemporary research tools to quickly improve human cancer care
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Benjamin D. Humphreys, M.D., Ph.D.
- Define cell hierarchies in kidney injury and repair and thereby identify the critical cell types in kidney repair and fibrosis
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Shin-ichiro Imai, M.D., Ph.D.
- Understanding the molecular mechanism of aging and longevity in mammals
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Sanjay Jain, M.D., Ph.D.
- Interactions between the nervous and genitourinary systems during development, molecular basis for heterogeneity in progenitors and their lineage commitments in the GU tract, injury and regeneration using animal models, mechanisms of malformations using organoids from iPSCs
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Patrick Y. Jay, M.D., Ph.D.
- Genetics and genomics of cardiac development and heart failure
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Aaron Johnson, Ph.D.
- Molecular mechanisms of skeletal and cardiac muscle development and disease
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Celeste M. Karch, Ph.D.
- Understanding the molecular and cellular mechanisms underlying tauopathies
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Charles Kaufman, MD, Ph.D.
- Understanding and modifying the mechanisms controlling the onset of melanoma cancer by integrating zebrafish models and human disease
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Daniel Kerschensteiner, M.D.
- Neural circuit assembly and visual processing in the retina and the brain
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Albert H. Kim, M.D., Ph.D.
- Signal transduction in malignant brain tumors and brain development
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Ramakrishna Kommagani, Ph.D.
- Understanding the cellular, biochemical, and molecular mechanisms that underlie reproductive tract function and its pathology
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S. Kerry Kornfeld, M.D., Ph.D.
- organismal aging; zinc homeostasis and roles of zinc during cell differentiation.
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Kristen L. Kroll, Ph.D.
- Transcriptional and epigenetic regulation of neural development and its dysregulation in neurodevelopmental disorders
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Kory J. Lavine, M.D., Ph.D.
- Identify signaling pathways that mediate cardiac tissue repair/regeneration and heart failure pathogenesis.
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Irfan J. Lodhi, Ph.D.
- The role of lipid metabolism pathways in the regulation of energy homeostasis.
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Fanxin Long, Ph.D.
- Developmental and regenerative biology of the mammalian skeleton
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Gregory D. Longmore, M.D.
- Cell Motility and Cancer Metastasis
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Liang Ma, Ph.D.
- Understanding genetic pathways regulating epithelial differentiation
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Susan Mackinnon, M.D.
- Investigation of peripheral nerve injury and regeneration
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Blair B. Madison, Ph.D.
- Utilize functional genomics to identify new genes and pathways that regulate epithelial transformation in the intestine
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Jeffrey Magee, M.D., Ph.D.
- Developmental context and genetic variation as underlying mechanisms of childhood cancer
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Moe Mahjoub, Ph.D.
- Molecular mechanisms of centrosome biogenesis and ciliogenesis, and their roles in development and disease
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Gabriel Mbalaviele, Ph.D.
- Role of inflammasomes in skeletal development and maintenance
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Audrey McAlinden, Ph.D.
- Molecular mechanisms regulating skeletal development
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Helen McNeill, Ph.D.
- Understand how tissue growth and tissue organization are coordinately regulated during normal development, and how loss of this control leads to human disease.
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Robert P. Mecham, Ph.D.
- Cell-matrix interactions, extracellular matrix and development, vascular development and disease
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Gretchen A. Meyer, Ph.D.
- Understanding how changes at the molecular and cellular level in skeletal muscle affect muscle structure and function
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Craig Micchelli, Ph.D.
- The biology of stem cells
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Jeffrey Milbrandt, M.D., Ph.D.
- Axonal degeneration, regulation of myelination, neuronal energetics and mitochondrial function in neuropathy and neurodegenerative disease
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Kathryn G. Miller, Ph.D.
- Function of actin-binding proteins in development
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Jeffrey R. Millman, Ph.D.
- The in vitro production and study of pancreatic insulin-producing β cells from human pluripotent stem cells for use in cellular replacement therapy and drug screening.
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Jason C. Mills, M.D., Ph.D.
- Developmental, molecular, and cellular biology of gastrointestinal epithelial stem cells and gastric cancer
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Jeffrey H. Miner, Ph.D.
- Human genetic kidney disease: Insights through mouse models
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Mayssa H. Mokalled, Ph.D.
- Mechanisms of neural regeneration using zebrafish and mouse model systems
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Kelle H. Moley, M.D.
- Murine preimplantation embryogenesis: the effects of maternal hyperglycemia and hyperinsulinemia on glucose transporter and blastocyst survival
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Josh L. Morgan, Ph.D.
- Use advanced cellular imaging techniques to investigate how neurons organize themselves into image processing circuits
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Samantha A. Morris, Ph.D.
- The study of gene regulatory networks to dissect and engineer cell fate of clinically relevant tissues such as the liver
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Kenneth M. Murphy, M.D., Ph.D.
- Selecting the correct immune response to pathogens – development of dendritic cells and lymphocyte subsets
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Indira U. Mysorekar, Ph.D.
- Mechanisms of mucosal defenses in the urinary bladder and placenta
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David M. Ornitz, M.D., Ph.D.
- FGF signaling in cardiovascular, lung, skeletal, and inner ear development, injury response, and regeneration
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Philip Osdoby, Ph.D.
- Bone remodeling cell and molecular events of osteoclast activity and development
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Zachary Pincus, Ph.D.
- Understanding inter-individual variability living systems
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David Queller, Ph.D.
- The evolution of sociality, cooperation, and cheating in a eukaryotic microbe, using experimental evolution, genomics, and other approaches
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Maria S. Remedi, Ph.D.
- Channels: diabetes, obesity and brain disorders
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Stacey L. Rentschler, M.D., Ph.D.
- Direct reprogramming of cells into specialized cardiac conduction tissues
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Deborah C. Rubin, M.D.
- Intestinal stem cells and the stem cell niche in intestinal injury/short bowel syndrome and colitis associated colon cancer
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David A. Rudnick, M.D., Ph.D.
- Molecular mechanisms of liver regeneration
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Lawrence B. Salkoff, Ph.D.
- How ion channels function in physiology and behavior
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Tim B. Schedl, Ph.D.
- Control of germline stem cells and meiotic development in C. elegans
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Erica L. Scheller, D.D.S., Ph.D.
- Impact of neuroendocrine signals on bone loss and marrow adiposity in diseases including periodontitis, arthritis, and diabetes
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Laura G. Schuettpelz, M.D., Ph.D.
- Regulation of hematopoietic stem cells (HSCs) by inflammation
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Lori A. Setton, Ph.D.
- Understanding the mechanisms for degeneration and regeneration of soft tissues of the musculoskeletal system, including the intervertebral disc, articular cartilage, and meniscus
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Lavinia Sheets, Ph.D.
- Defining pathological changes in noise-exposed sensory hair cells and identifying pathways that promote repair
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Gary A. Silverman, M.D., Ph.D.
- The cellular response to life threatening human diseases.
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James B. Skeath, Ph.D.
- Genetic analysis of neural and muscular development in the Drosophila embryo
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Lilianna Solnica-Krezel, Ph.D.
- Inductive and morphogenetic processes that establish and shape germ layers during vertebrate embryogenesis, using zebrafish and embryonic stem cell models
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David H. Spencer, M.D., Ph.D.
- My research program studies epigenetic gene regulation in cancer, with a specific emphasis on understanding how mutations in acute myeloid leukemia (AML) perturb the epigenome to alter gene expression and cause leukemia.
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Thaddeus S. Stappenbeck, Ph.D., M.D.
- Molecular interactions between intestinal epithelial stem cells and their niche
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Cristina de Guzman Strong, Ph.D.
- Genomics of Skin Barrier: Development and Disease
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Christopher M. Sturgeon, Ph.D.
- Investigating the mechanisms underlying human hematopoietic development, using the in vitro differentiation of embryonic stem cells and induced pluripotent stem cells as a model system
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Paul H. Taghert, Ph.D.
- Circadian physiology and behavior
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Steven L. Teitelbaum, M.D.
- Molecular mechanisms of osteoclast differentiation and bone resorption
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Jessica E. Wagenseil, D.Sc.
- Cardiovascular mechanics, how the heart and blood vessels respond to mechanical forces
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Mark E. Warchol, Ph.D.
- Mechanisms of development, injury and repair in the vertebrate auditory system
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