Corvin Arveseth

MSTP in PhD Training

Program: Immunology

Current advisor: Laura G. Schuettpelz, MD, PhD

Undergraduate university: University of Utah, 2021

Enrollment year: 2022

Research summary
Hematopoietic stem cell responses and changes in differentiation due to inflammation and stress

One mechanism by which hematopoietic stem cells (HSCs) resist inflammatory stress is through upregulation of the tetraspanin family member CD53. My project is focused on examining how expression of CD53 influences HSCs which lack the epigenetic modifiers DNMT3a or Tet2 (a common occurrence in several malignancies of the blood).

Graduate publications
Selli ME, Landmann JH, Arveseth C, Singh N. 2023 Inducing T cell dysfunction by chronic stimulation of CAR-engineered T cells targeting cancer cells in suspension cultures. STAR Protocols, 4(1):101954. PMCID: PMC9826863