Ji-Sun Kwon

Program: Computational and Systems Biology

Current advisor: Andrew Yoo, PhD

Undergraduate university: Seoul Woman’s University, 2009

Enrollment year: 2019

Research summary

Graduate publications
Sun Z, Kwon JS, Ren Y, Chen S, Walker CK, Lu X, Cates K, Karahan H, Sviben S, Fitzpatrick JAJ, Valdez C, Houlden H, Karch CM, Bateman RJ, Sato C, Mennerick SJ, Diamond MI, Kim J, Tanzi RE, Holtzman DM, Yoo AS.. 2024 Modeling late-onset Alzheimer’s disease neuropathology via direct neuronal reprogramming. Science, 385(6708):adl2992. PMCID:

Paryani F, Kwon JS, Ng CW, Jakubiak K, Madden N, Ofori K, Tang A, Lu H, Xia S, Li J, Mahajan A, Davidson SM, Basile AO, McHugh C, Vonsattel JP, Hickman R, Zody MC, Housman DE, Goldman JE, Yoo AS, Menon V, Al-Dalahmah O. 2024 Multi-omic analysis of Huntington’s disease reveals a compensatory astrocyte state. Nat Commun, 15(1):6742. PMCID:

Capano LS,, Sato C, Ficulle E, Yu A, Horie K, Kwon J-S, Burbach KF, Barthélemy NR, Fox SG, Karch CM, Bateman RJ, Houlden H, Morimoto RI, Holtzman DM, Duff KE, Yoo AS. 2022 Recapitulation of endogenous 4R tau expression and formation of insoluble tau in directly reprogrammed human neurons. Cell Stem Cell, 29(6):918-932.e8. PMCID: PMC9176216

Cates K, McCoy MJ, Kwon JS, Liu Y, Abernathy DG, Zhang B, Liu S, Gontarz P, Kim WK, Chen S, Kong W, Ho JN, Burbach KF, Gabel HW, Morris SA, Yoo AS. 2021 Deconstructing Stepwise Fate Conversion of Human Fibroblasts to Neurons by MicroRNAs. Cell Stem Cell, 28(1)::127-140.e9. PMCID: PMC7796891