Haewon Shin

Program: Computational and Systems Biology

Current advisor: Kory J. Lavine, MD, PhD

Undergraduate university: Washington University, 2021

Enrollment year: 2021

Research summary
Examining Transcriptomic Changes in Cardiac Amyloidosis at the Single-Cell Level

Cardiac amyloidosis is one of the leading causes of restrictive cardiomyopathy, albeit underdiagnosed and poorly understood with respect to the interactions between the abnormal protein deposition and the body’s immune response inducing remodeling in the cardiac tissue. My work focuses on leveraging different single-nucleus RNA sequencing platforms to map the transcriptomic landscape of cardiac muscle affected by transthyretin (ATTR) amyloidosis.

Graduate publications