Courtney Karl

Program: Molecular Microbiology and Microbial Pathogenesis

Current advisor: Michael S. Diamond, MD, PhD

Undergraduate university: Truman State University, 2020

Enrollment year: 2020

Research summary
Elucidating mechanisms by which helminths modulate host antiviral immunity

Graduate publications
Desai P, Karl CE, Ying B, Liang CY, Garcia-Salum T, Santana AC, Ten-Caten F, Joseph F Urban Jr, Elbashir SM, Edwards DK, Ribeiro SP, Thackray LB, Sekaly RP, Diamond MS. 2024 Intestinal helminth infection impairs vaccine-induced T cell responses and protection against SARS-CoV-2 in mice. Sci Transl Med, 16(761)::eado1941. PMCID:

Mackin SR, Desai P, Whitener BM, Karl CE, Liu M, Baric RS, Edwards DK, Chicz TM, McNamara RP, Alter G, Diamond MS. 2023 Fc-γR-dependent antibody effector functions are required for vaccine-mediated protection against antigen-shifted variants of SARS-CoV-2. Nat Microbiol, 8(4):569-80. PMCID: PMC10797606

Chong Z, Karl CE, Halfmann PJ, Kawaoka Y, Winkler ES, Keeler SP, Holtzman MJ, Yu J, Diamond MS. 2022 Nasally delivered interferon-λ protects mice against infection by SARS-CoV-2 variants including Omicron. Cell Rep, 39(6):110799. PMCID: PMC9021357

Ying B, Whitener B, VanBlargan LA, Hassan AO, Shrihari S, Liang CY, Karl CE, Mackin S, Chen RE, Kafai NM, Wilks SH, Smith DJ, Carreño JM, Singh G, Krammer F, Carfi A, Elbashir SM, Edwards DK, Thackray LB, Diamond MS. 2022 Protective activity of mRNA vaccines against ancestral and variant SARS-CoV-2 strains. Sci Transl Med, 14(630):eabm3302. PMCID: PMC8817234