Alekhya Parvathaneni

Program: Molecular Genetics and Genomics

Current advisor: Kory J. Lavine, MD, PhD

Undergraduate university: Santa Clara University, 2020

Enrollment year: 2022

Research summary
Underlying immune mechanisms of heart failure and cardiomyopathies

IL-1B has been implicated in macrophage-fibroblast crosstalk, and is linked to changes in differentiation trajectory, gene regulatory networks, etc. towards a fibroblast phenotype that is pro-fibrotic. My project seeks to understand the role that IL-1B plays in monocyte fate specification and the differentiation of macrophages into different cell states in the heart.

Graduate publications