Natasha Ramakrishnan

Program: Molecular Genetics and Genomics

Current advisor: Priyanka Verma, PhD

Undergraduate university: Washington University, 2021

Enrollment year: 2021

Research summary
Investigating the causes and consequences of genomic instability in cyclin E1-high ovarian cancers

Investigating the causes and consequences of genomic instability in cyclin E1-high ovarian cancers

Graduate publications
Ramakrishnan N, Malachowski T, Verma P. 2024 A high-content flow cytometry and dual CRISPR-Cas9 based platform to quantify genetic interactions. Methods Cell Biol, 182():299-312. PMCID:

Ramakrishnan N, Weaver TM, Aubuchhon LN, Woldegerima A, Just T, Song K, Vindigni A, Freudenthal BD, Priyanka Verma P. 2024 Nucleolytic processing of abasic sites underlies PARP inhibitor hypersensitivity in ALC1-deficient BRCA mutant cancer cells. Nat Commun, 15(1):6343. PMCID: PMC11283519

Ramakrishnan N, Haseljic E, Verma P. 2023 Quantifying Replication Stress in Ovarian Cancer Cells Using Single-Stranded DNA Immunofluorescence. J Vis Exp, 10():192. PMCID:

Meroni A, Grosser J, Agashe S, Ramakrishnan N, Jackson J, Verma P, Baranello L, Vindigni A. 2022 NEDDylated Cullin 3 mediates the adaptive response to topoisomerase 1 inhibitors. Sci Adv, 8(49):eabq0648. PMCID: PMC9733930

Mathyer ME, Brettmann EA, Schmidt AD, Goodwin ZA, Oh IY, Quiggle AM, Tycksen E, Ramakrishnan N, Matkovich SJ, Guttman-Yassky E, Edwards JR, de Guzman Strong C. 2021 Selective sweep for an enhancer involucrin allele identifies skin barrier adaptation out of Africa. Nat Commun, 12(1):2557. PMCID: PMC8105351