Irenaeus Chi-Chung Chan

Program: Cancer Biology

Current advisor: Kelly L. Bolton, MD, PhD

Undergraduate university: University of Guelph, 2016

Enrollment year: 2024

Research summary

Graduate publications
Hubbard AK, Brown DW, Liu J, Chan IC, Zhou W, Genovese G, DePaulis A, Srinivasan S, Lin SH, Blechter B, Buller ID, Zeng Q, Cao Y, Huang WY, Freedman ND, Zhang H, Dutta D, Chanock SJ, Bolton KL, Machiela MJ.. 2025 Integration of Germline and Somatic Variation Improves Chronic Lymphocytic Leukemia Risk Stratification. Cancer Res, 85(14):2743-52. PMCID: PMC12263322

Liu J, Tran D, Xue L, Wiley BJ, Vlasschaert C, Watson CJ, MacGregor HAJ, Zong X, Chan ICC, Das I, Uddin MM, Niroula A, Griffin G, Ebert BL, Mack T, Pershad Y, Sharber B, Berger M, Zehir A, Ptashkin R, Levine RL, Papaemmanuil E, Joseph V, Gao T, Kemel Y, Mandelker D, Stopsack KH, Pharoah PDP, Mukherjee S, Ding L, Cao Y, Walter MJ, Blundell JR, Chatterjee N, Offit K, Godley LA, Link DC, Stadler ZK, Bick AG, Natarajan P, Bolton KL. 2025 Germline genetic variation impacts clonal hematopoiesis landscape and progression to malignancy. Nat Genet, ():Online ahead of print. PMCID:

Machiela MJ, Wong WSW, Mai JZ, Karyadi DM, Drozdovitch V, Chan I, Vij V, Zhou W, Luo W, Wu D, Hutchinson A, Jones K, Hicks B, Bakhanova E, Chumak V, Gudzenko N, Kryuchkov V, Golovanov I, Bolton K, Cahoon EK, Morton LM, Bazyka D, Chanock SJ. 2025 Risk of clonal hematopoiesis in families exposed to radiation following the Chornobyl accident. Carcinogenesis, 63(3):bgaf056. PMCID: PMC12558148